(Q24302528)

CYLD lysine 63 deubiquitinase

GOA release 2020-03-11

1 reference

negative regulation of canonical Wnt signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

protein ubiquitination

1 reference

8

Hans Clevers

Hans

Clevers

1 reference

9 December 2023

Madelon M Maurice

9

Madelon M

Maurice

1 reference

9 December 2023

Mariola J Edelmann

4

Mariola J

Edelmann

1 reference

9 December 2023

Benedikt M Kessler

7

Benedikt M

Kessler

1 reference

9 December 2023

Daniele V F Tauriello

1

Daniele V F

Tauriello

1 reference

9 December 2023

Andrea Haegebarth

2

Andrea

Haegebarth

1 reference

9 December 2023

Ineke Kuper

3

Ineke

Kuper

1 reference

9 December 2023

Marre Henraat

5

Marre

Henraat

1 reference

9 December 2023

Marijke R Canninga-van Dijk

6

Marijke R

The novel functions of ubiquitination in signaling

Canninga-van Dijk

1 reference

9 December 2023

language of work or name

English

0 references

publication date

12 March 2010

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published in

Molecular Cell

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volume

37

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issue

5

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page(s)

607-19

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Role of ubiquitin- and Ubl-binding proteins in cell signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

A genomic and functional inventory of deubiquitinating enzymes

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Wnt/beta-catenin signaling in development and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Regulation of planar cell polarity by Smurf ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

A mechanism for Wnt coreceptor activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Identification of the familial cylindromatosis tumour-suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Analysis of DNA copy number aberrations in hepatitis C virus-associated hepatocellular carcinomas by conventional CGH and array CGH.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Scratching the surface of skin development

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Direct activation of protein kinases by unanchored polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Regulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Reduced expression of CYLD in human colon and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The C-terminal cytoplasmic Lys-thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The dishevelled protein is modified by wingless signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The Wnt signaling pathway in development and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Modification of proteins by ubiquitin and ubiquitin-like proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Dynamic recruitment of axin by Dishevelled protein assemblies

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021

Wnt/Frizzled signaling in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2010.01.035

7 January 2021