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Sirtuin functions in health and disease
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instance of
scholarly article
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review article
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stated in
Europe PubMed Central
title
Sirtuin functions in health and disease
(English)
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main subject
Sirtuin 6
1 reference
stated in
GOA release 2020-03-11
sirtuin 3
1 reference
stated in
GOA release 2020-03-11
sirtuin 1
1 reference
stated in
GOA release 2020-03-11
Sirtuin 5
1 reference
stated in
GOA release 2020-03-11
Sirtuin 2
1 reference
stated in
GOA release 2020-03-11
Sirtuin 4
1 reference
stated in
GOA release 2020-03-11
protein ADP-ribosylation
1 reference
stated in
GOA release 2020-03-11
author
Johan Auwerx
series ordinal
3
0 references
Kristina Schoonjans
series ordinal
2
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author name string
Hiroyasu Yamamoto
series ordinal
1
0 references
language of work or name
English
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publication date
August 2007
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published in
Molecular Endocrinology
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volume
21
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page(s)
1745-55
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issue
8
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cites work
Caloric intake and the risk of Alzheimer disease.
1 reference
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Crossref
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7 January 2021
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Disorders of glutamate metabolism
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Crossref
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7 January 2021
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Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
1 reference
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7 January 2021
based on heuristic
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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assembly of the SIR complex and its regulation by O-acetyl-ADP-ribose, a product of NAD-dependent histone deacetylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
inferred from DOI database lookup
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
inferred from DOI database lookup
The retardation of aging by caloric restriction: its significance in the transgenic era.
1 reference
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Crossref
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https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man
1 reference
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Crossref
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https://api.crossref.org/works/10.1210%2FME.2007-0079
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7 January 2021
based on heuristic
inferred from DOI database lookup
Severe ultrastructural mitochondrial changes in lymphoblasts homozygous for Huntington disease mutation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of the Saccharomyces cerevisiae DAL5 gene family and identification of the high affinity nicotinic acid permease TNA1 (YGR260w).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extrachromosomal rDNA circles--a cause of aging in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conserved regulatory system for aging
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative control of p53 by Sir2alpha promotes cell survival under stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular biology of the SIR proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The energetics of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of mammalian DNA polymerase-beta in base-excision repair.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the histone deacetylase SIRT2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resveratrol improves health and survival of mice on a high-calorie diet
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calorie restriction, SIRT1 and metabolism: understanding longevity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Splicing regulates NAD metabolite binding to histone macroH2A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered sirtuin expression is associated with node-positive breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the tumor suppressor p53 in spermatogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Take five--BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3 proteins; bringing new definitions to scaffolding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Post-translational modifications and activation of p53 by genotoxic stresses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid plaque core protein in Alzheimer disease and Down syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amyloid beta-protein and the genetics of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin resistance, affective disorders, and Alzheimer's disease: review and hypothesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calorie restriction extends yeast life span by lowering the level of NADH.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small molecule regulation of Sir2 protein deacetylases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axonal self-destruction and neurodegeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HST2 mediates SIR2-independent life-span extension by calorie restriction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease: the amyloid cascade hypothesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hormonal control of androgen receptor function through SIRT1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Sir2 family of protein deacetylases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PPAR(gamma) and glucose homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alzheimer's disease: genes, proteins, and therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1210%2FME.2007-0079
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1210/ME.2007-0079
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
266977
OpenCitations bibliographic resource ID
266977
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
266977
PubMed ID
17456799
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
266977
ResearchGate publication ID
6371964
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