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Regulation of the Wnt signaling pathway by disabled-2 (Dab2)
scientific article
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scholarly article
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title
Regulation of the Wnt signaling pathway by disabled-2 (Dab2)
(English)
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main subject
disability
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Dishevelled segment polarity protein 3
1 reference
stated in
GOA release 2020-03-11
Dishevelled segment polarity protein 2
1 reference
stated in
GOA release 2020-03-11
Dishevelled segment polarity protein 1
1 reference
stated in
GOA release 2020-03-11
DAB adaptor protein 2
1 reference
stated in
GOA release 2020-03-11
Wnt signaling pathway, planar cell polarity pathway
1 reference
stated in
GOA release 2020-03-11
Axin 1
1 reference
stated in
GOA release 2020-03-11
Dishevelled segment polarity protein 2
1 reference
stated in
GOA release 2020-03-11
Dishevelled segment polarity protein 3
1 reference
stated in
GOA release 2020-03-11
Disabled 2, mitogen-responsive phosphoprotein
1 reference
stated in
GOA release 2020-03-11
author name string
B A Hocevar
series ordinal
1
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F Mou
series ordinal
2
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J L Rennolds
series ordinal
3
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S M Morris
series ordinal
4
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J A Cooper
series ordinal
5
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P H Howe
series ordinal
6
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language of work or name
English
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publication date
16 June 2003
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published in
The EMBO Journal
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volume
22
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page(s)
3084-94
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issue
12
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cites work
Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
retrieved
19 March 2017
Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
retrieved
19 March 2017
The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.
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PubMed Central
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19 March 2017
Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization
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PubMed Central
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19 March 2017
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Identification of c-MYC as a target of the APC pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
retrieved
19 March 2017
Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
retrieved
19 March 2017
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Signal transduction by the Wnt family of ligands
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Human dishevelled genes constitute a DHR-containing multigene family
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Wnt signaling and cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Signaling through scaffold, anchoring, and adaptor proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
retrieved
19 March 2017
Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
retrieved
19 March 2017
Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
The inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal cascade. DOC-2/DAB2-mediated inhibition of ERK phosphorylation via binding to Grb2
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Regulation of rat DOC-2 gene during castration-induced rat ventral prostate degeneration and its growth inhibitory function in human prostatic carcinoma cells
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PubMed Central
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19 March 2017
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
The dishevelled protein is modified by wingless signaling in Drosophila
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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19 March 2017
Wnt signaling: a common theme in animal development
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PubMed Central
reference URL
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7 April 2017
Linking colorectal cancer to Wnt signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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7 April 2017
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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7 April 2017
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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7 April 2017
The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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27 September 2017
Identification of the Axin and Frat binding region of glycogen synthase kinase-3.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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27 September 2017
Doc-2/hDab2 expression is up-regulated in primary pancreatic cancer but reduced in metastasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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27 September 2017
APC truncation and increased beta-catenin levels in a human breast cancer cell line
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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27 September 2017
Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression
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PubMed Central
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27 September 2017
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
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PubMed Central
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27 September 2017
Cytoskeletal reorganization by soluble Wnt-3a protein signalling
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27 September 2017
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
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PubMed Central
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27 September 2017
Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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27 September 2017
Casein kinase 2 associates with and phosphorylates dishevelled
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=162138
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27 September 2017
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27 September 2017
Isolation and characterization of mouse dishevelled-3.
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27 September 2017
JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates
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30 May 2018
Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells
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30 May 2018
Inducible regulatory elements in the human cyclin D1 promoter
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30 May 2018
Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates.
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29 November 2018
Casein kinase I transduces Wnt signals.
1 reference
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29 November 2018
Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled.
1 reference
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PubMed Central
reference URL
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29 November 2018
p96, a MAPK-related protein, is consistently downregulated during mouse mammary carcinogenesis
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/12805222
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/EMBOJ/CDG286
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3147576
OpenCitations bibliographic resource ID
3147576
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3147576
PMCID
162138
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3147576
PubMed ID
12805222
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3147576
ResearchGate publication ID
10709976
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