(Q24306518)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

Cyclin dependent kinase 5 regulatory subunit 1

5 November 2019

main subject

1 reference

GOA release 2020-03-11

Lemur tyrosine kinase 2

1 reference

GOA release 2020-03-11

author

Kwok-Fai Lau

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Steve Banner

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Declan McLoughlin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

7

P Nigel Leigh

1 reference

5 November 2019

Sashi Kesavapany

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Steven Ackerley

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Stephen J A Shemilt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Jonathan D Cooper

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Christopher E Shaw

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Christopher C J Miller

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 June 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

4975-4983

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

CDK-5-mediated neurofilament phosphorylation in SHSY5Y human neuroblastoma cells

5 November 2019

cites work

1 reference

12 December 2020

Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous

1 reference

12 December 2020

Immunohistochemical localization of CDK5 activator p39 in the rat brain

1 reference

12 December 2020

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

12 December 2020

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

1 reference

12 December 2020

Phosphorylation of neurofilament heavy chain side-arms by stress activated protein kinase-1b/Jun N-terminal kinase-3

1 reference

12 December 2020

p39 activates cdk5 in neurons, and is associated with the actin cytoskeleton

1 reference

12 December 2020

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

1 reference

12 December 2020

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

1 reference

12 December 2020

Interaction of neuronal Cdc2-like protein kinase with microtubule-associated protein tau.

1 reference

12 December 2020

Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase

1 reference

12 December 2020

Tau phosphorylation at serine 396 and serine 404 by human recombinant tau protein kinase II inhibits tau's ability to promote microtubule assembly

1 reference

12 December 2020

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

12 December 2020

The cyclin-dependent kinase Cdk5 controls multiple aspects of axon patterning in vivo.

1 reference

12 December 2020

Glutamate slows axonal transport of neurofilaments in transfected neurons

1 reference

12 December 2020

Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells

1 reference

12 December 2020

Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1

1 reference

12 December 2020

Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2

1 reference

12 December 2020

Neuronal cyclin-dependent kinase 5 activity is critical for survival.

1 reference

12 December 2020

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

1 reference

12 December 2020

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

1 reference

12 December 2020

p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction

1 reference

12 December 2020

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain

1 reference

12 December 2020

The role of the Cdk5--p35 kinase in neuronal development

1 reference

12 December 2020

Cyclin-dependent protein kinase 5 (Cdk5) and the regulation of neurofilament metabolism

1 reference

12 December 2020

A Cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons

1 reference

12 December 2020

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

1 reference

12 December 2020

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

1 reference

12 December 2020

Phosphorylation of protein phosphatase inhibitor-1 by Cdk5

1 reference

12 December 2020

Characterization of an alternatively spliced AATYK mRNA: expression pattern of AATYK in the brain and neuronal cells

1 reference

12 December 2020

Neuronal Cdc2-like protein kinase (Cdk5/p25) is associated with protein phosphatase 1 and phosphorylates inhibitor-2

1 reference

12 December 2020

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

12 December 2020

p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment

1 reference

12 December 2020

1 reference

12 December 2020

Phosphorylation of Pak1 by the p35/Cdk5 kinase affects neuronal morphology

1 reference

12 December 2020

Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway

1 reference

12 December 2020

Neocortical cell migration: GABAergic neurons and cells in layers I and VI move in a cyclin-dependent kinase 5-independent manner.

1 reference

12 December 2020

The Cdk5-p35 kinase associates with the Golgi apparatus and regulates membrane traffic

1 reference

12 December 2020

HUGE: a database for human large proteins identified in the Kazusa cDNA sequencing project

1 reference

12 December 2020

Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3.

1 reference

12 December 2020

Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.

1 reference

12 December 2020

Cyclin-dependent kinase 5 is required for associative learning

1 reference

12 December 2020

Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain.

1 reference

12 December 2020

Cyclin-dependent kinase-5/p35 phosphorylates Presenilin 1 to regulate carboxy-terminal fragment stability.

1 reference

12 December 2020

Cdk5 phosphorylates p53 and regulates its activity

1 reference

12 December 2020

Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A

1 reference

12 December 2020

Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling

1 reference

12 December 2020

Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model.

1 reference

12 December 2020

The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner

1 reference

12 December 2020

Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau.

1 reference

12 December 2020

Expression of the Fe65 adapter protein in adult and developing mouse brain.

1 reference

12 December 2020

Expression, purification and characterization of the ubiquitous protein kinase C-related kinase 1.

1 reference

12 December 2020

Localization of neuronal and glial glutamate transporters

1 reference

12 December 2020

Precursor of cdk5 activator, the 23 kDa subunit of tau protein kinase II: its sequence and developmental change in brain.

1 reference

12 December 2020

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

12 December 2020

A brain-specific activator of cyclin-dependent kinase 5.

1 reference

12 December 2020

Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments.

1 reference

12 December 2020

1 reference

12 December 2020

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

1 reference

12 December 2020

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization

1 reference

12 December 2020

Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5.

1 reference

12 December 2020

Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35

1 reference

12 December 2020

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

1 reference

12 December 2020

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

1 reference

12 December 2020

Cellular and regional distribution of the glutamate transporter GLAST in the CNS of rats: nonradioactive in situ hybridization and comparative immunocytochemistry.

1 reference

12 December 2020

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

1 reference

12 December 2020

Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein.

1 reference

12 December 2020

Analysis of the expression, distribution and function of cyclin dependent kinase 5 (cdk5) in developing cerebellar macroneurons.

1 reference

12 December 2020

Phosphorylation of neurofilament heavy-chain side-arm fragments by cyclin-dependent kinase-5 and glycogen synthase kinase-3alpha in transfected cells

1 reference

12 December 2020

Phosphorylation by neuronal cdc2-like protein kinase promotes dimerization of Tau protein in vitro

1 reference

12 December 2020

Neuronal Cdc2-like kinases: neuron-specific forms of Cdk5.

1 reference

12 December 2020

Cyclin D2 interacts with cdk-5 and modulates cellular cdk-5/p35 activity

1 reference

12 December 2020

Association of neurofilament proteins with neuronal Cdk5 activator.

1 reference

12 December 2020

AATYK: a novel tyrosine kinase induced during growth arrest and apoptosis of myeloid cells

1 reference

12 December 2020

Characterization of tau phosphorylation in glycogen synthase kinase-3beta and cyclin dependent kinase-5 activator (p23) transfected cells

1 reference

12 December 2020

Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system.

1 reference

12 December 2020

Cyclin-dependent kinase-5 is associated with lipofuscin in motor neurones in amyotrophic lateral sclerosis

1 reference

12 December 2020

Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex

1 reference

12 December 2020

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

1 reference

12 December 2020

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

1 reference

12 December 2020

Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth.

1 reference

12 December 2020

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

1 reference

12 December 2020

10.1523/JNEUROSCI.23-12-04975.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832520%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference