(Q24310855)

positive regulation of apoptotic process

GOA release 2020-03-11

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GOA release 2020-03-11

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Xuemin Xu

1

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Yong-chang Shi

2

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Wei Gao

3

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Guozhang Mao

4

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Guojun Zhao

5

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Sudesh Agrawal

6

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Guy M Chisolm

7

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Dexin Sui

8

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Mei-Zhen Cui

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

13 December 2002

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published in

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volume

277

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issue

50

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page(s)

48913-22

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cites work

Amyloid beta-protein and the genetics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

The gene defects responsible for familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Regulation of apoptosis by presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Simultaneous detection of cyclin B1, p105, and DNA content provides complete cell cycle phase fraction analysis of cells that endoreduplicate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

The chaperone function of hsp70 is required for protection against stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Caspases: killer proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Apoptotic pathways: the roads to ruin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Double labelling of subcellular structures with organelle-targeted GFP mutants in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Mitochondrial carrier proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

The import route of ADP/ATP carrier into mitochondria separates from the general import pathway of cleavable preproteins at the trans side of the outer membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Presenilin-1 is located in rat mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Apoptosis signaling by death receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Presenilin 1 protein directly interacts with Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Interaction of Alzheimer's presenilin-1 and presenilin-2 with Bcl-X(L). A potential role in modulating the threshold of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Bcl-2-family proteins: the role of the BH3 domain in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Phosphorylation, subcellular localization, and membrane orientation of the Alzheimer's disease-associated presenilins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Cell surface expression of the Alzheimer disease-related presenilin proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Presenilin-1 protects against neuronal apoptosis caused by its interacting protein PAG

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

Methods for detecting and quantifying apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Overexpression of a C-terminal fragment of presenilin 1 delays anti-Fas induced apoptosis in Jurkat cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Contrasting role of presenilin-1 and presenilin-2 in neuronal differentiation in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209613200

7 January 2021

Identifiers

DOI

10.1074/JBC.M209613200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12377771

1 reference

Consolidated OpenCitations Corpus – April 2017