(Q24311504)

positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

7

Neil Osheroff

0 references

author name string

Leyma P De Haro

1

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Justin Wray

2

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Elizabeth A Williamson

3

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Stephen T Durant

4

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Lori Corwin

5

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Amanda C Gentry

6

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Suk-Hee Lee

8

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Robert Hromas

9

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Jac A Nickoloff

Creative Commons Attribution-NonCommercial 2.5 Generic

10

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language of work or name

English

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publication date

September 2010

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published in

Nucleic Acids Research

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volume

38

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issue

17

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page(s)

5681-91

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copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2943610/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells

19 March 2017

1 reference

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The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation

19 March 2017

1 reference

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Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair

19 March 2017

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Birth of a chimeric primate gene by capture of the transposase gene from a mobile element

19 March 2017

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The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair

19 March 2017

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Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

19 March 2017

1 reference

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Cellular roles of dna topoisomerases: a molecular perspective

19 March 2017

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

19 March 2017

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A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

19 March 2017

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Rad52 forms DNA repair and recombination centers during S phase

19 March 2017

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

19 March 2017

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PCNA, the maestro of the replication fork

19 March 2017

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Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

19 March 2017

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PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

19 March 2017

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Metnase mediates chromosome decatenation in acute leukemia cells

27 September 2017

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Mechanisms of dealing with DNA damage-induced replication problems

27 September 2017

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Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

27 September 2017

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Distinct RAD51 associations with RAD52 and BCCIP in response to DNA damage and replication stress

27 September 2017

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The MCM helicase: linking checkpoints to the replication fork

27 September 2017

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Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress

27 September 2017

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Role of non-homologous end joining (NHEJ) in maintaining genomic integrity

27 September 2017

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Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses

27 September 2017

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Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells

27 September 2017

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Human cell DNA replication is mediated by a discrete multiprotein complex

27 September 2017

1 reference

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DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

27 September 2017

1 reference

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Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells

27 September 2017

1 reference

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DNA-PKcs and ATM co-regulate DNA double-strand break repair

27 September 2017

1 reference

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Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B.

30 May 2018

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ATR and H2AX cooperate in maintaining genome stability under replication stress

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943610

The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943610

Ino80 chromatin remodeling complex promotes recovery of stalled replication forks

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943610

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943610

gammaH2AX as a checkpoint maintenance signal.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943610

Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks

29 November 2018

1 reference

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Role for BLM in replication-fork restart and suppression of origin firing after replicative stress

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20457750