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Inhibition of IkappaB kinase by vaccinia virus virulence factor B14
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Europe PubMed Central
PMC publication ID
2233672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
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2 January 2020
title
Inhibition of IkappaB kinase by vaccinia virus virulence factor B14
(English)
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Europe PubMed Central
PMC publication ID
2233672
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
main subject
virulence
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Inhibitor of kappaB kinase beta
1 reference
stated in
GOA release 2020-03-11
Inhibitor of nuclear factor kappa-B kinase subunit alpha
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stated in
GOA release 2020-03-11
Inhibitor of kappaB kinase gamma
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GOA release 2020-03-11
Vaccinia virus
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vaccinia virus
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author
Ron A-J Chen
series ordinal
1
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Europe PubMed Central
PMC publication ID
2233672
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
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2 January 2020
Geoffrey Lilley Smith
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5
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Geoffrey L Smith
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Europe PubMed Central
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2233672
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
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2 January 2020
author name string
Grigory Ryzhakov
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2
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Europe PubMed Central
PMC publication ID
2233672
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2 January 2020
Samantha Cooray
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3
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Europe PubMed Central
PMC publication ID
2233672
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
Felix Randow
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4
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Europe PubMed Central
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2233672
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2 January 2020
language of work or name
English
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publication date
1 February 2008
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2233672
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retrieved
2 January 2020
published in
PLOS Pathogens
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Europe PubMed Central
PMC publication ID
2233672
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
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2 January 2020
volume
4
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Europe PubMed Central
PMC publication ID
2233672
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
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2 January 2020
issue
2
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Europe PubMed Central
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2233672
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2 January 2020
page(s)
e22
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Europe PubMed Central
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2233672
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retrieved
2 January 2020
copyright license
Creative Commons Attribution 4.0 International
start time
8 February 2008
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April 2022 Public Data File from Crossref
copyright status
copyrighted
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cites work
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein
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PubMed Central
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19 March 2017
Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis
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19 March 2017
Vaccinia virus protein A52R activates p38 mitogen-activated protein kinase and potentiates lipopolysaccharide-induced interleukin-10
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PubMed Central
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19 March 2017
A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter
1 reference
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PubMed Central
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19 March 2017
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
1 reference
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PubMed Central
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19 March 2017
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP
1 reference
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PubMed Central
reference URL
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19 March 2017
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
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19 March 2017
Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
Integrating cell-signalling pathways with NF-kappaB and IKK function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
Regulation and function of IKK and IKK-related kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
High-throughput mapping of a dynamic signaling network in mammalian cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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19 March 2017
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
retrieved
19 March 2017
Signaling to NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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7 April 2017
Missing pieces in the NF-kappaB puzzle
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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7 April 2017
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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7 April 2017
Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Poxviral regulation of the host NF-kappaB response: the vaccinia virus M2L protein inhibits induction of NF-kappaB activation via an ERK2 pathway in virus-infected human embryonic kidney cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Evasion of innate immunity by vaccinia virus
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PubMed Central
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27 September 2017
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
A20 is a negative regulator of IFN regulatory factor 3 signaling.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Vaccinia virus F1L protein is a tail-anchored protein that functions at the mitochondria to inhibit apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
IkappaB kinases: key regulators of the NF-kappaB pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Viral appropriation of apoptotic and NF-kappaB signaling pathways
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
The vaccinia virus K1L gene product inhibits host NF-kappaB activation by preventing IkappaBalpha degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Poxvirus genomes: a phylogenetic analysis
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PubMed Central
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27 September 2017
NF-kappaB and virus infection: who controls whom
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PubMed Central
reference URL
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27 September 2017
The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
Poxviruses and immune evasion
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence
1 reference
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PubMed Central
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27 September 2017
Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-kappaB activation
1 reference
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PubMed Central
reference URL
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Immunology 101 at poxvirus U: immune evasion genes
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PubMed Central
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A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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27 September 2017
The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation
1 reference
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PubMed Central
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27 September 2017
Vaccinia virus immune evasion
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PubMed Central
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27 September 2017
Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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30 May 2018
Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the right inverted terminal repeat
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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30 May 2018
Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
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29 November 2018
Blockade of chemokine activity by a soluble chemokine binding protein from vaccinia virus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2233672
retrieved
29 November 2018
Identifiers
DOI
10.1371/JOURNAL.PPAT.0040022
1 reference
stated in
Europe PubMed Central
PMC publication ID
2233672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
PMC publication ID
2233672
1 reference
stated in
Europe PubMed Central
PMC publication ID
2233672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
PubMed publication ID
18266467
1 reference
stated in
Europe PubMed Central
PMC publication ID
2233672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18266467%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 January 2020
ResearchGate publication ID
5586582
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