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BRI2 (ITM2b) inhibits Abeta deposition in vivo
scientific article
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instance of
scholarly article
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title
BRI2 (ITM2b) inhibits Abeta deposition in vivo
(English)
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main subject
Integral membrane protein 2B
1 reference
stated in
GOA release 2020-03-11
negative regulation of amyloid precursor protein biosynthetic process
1 reference
stated in
GOA release 2020-03-11
author
Jungsu Kim
object named as
Jungsu Kim
series ordinal
1
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Dennis W. Dickson
object named as
Dennis Dickson
series ordinal
18
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Steven G. Younkin
series ordinal
16
object named as
Steven G Younkin
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Neill R Graff-Radford
series ordinal
17
object named as
Neill Graff-Radford
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author name string
Victor M Miller
series ordinal
2
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Yona Levites
series ordinal
3
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Karen Jansen West
series ordinal
4
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Craig W Zwizinski
series ordinal
5
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Brenda D Moore
series ordinal
6
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Fredrick J Troendle
series ordinal
7
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Maralyssa Bann
series ordinal
8
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Christophe Verbeeck
series ordinal
9
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Robert W Price
series ordinal
10
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Lisa Smithson
series ordinal
11
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Leilani Sonoda
series ordinal
12
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Kayleigh Wagg
series ordinal
13
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Vijayaraghavan Rangachari
series ordinal
14
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Fanggeng Zou
series ordinal
15
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Terrone Rosenberry
series ordinal
19
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Todd E Golde
series ordinal
20
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language of work or name
English
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publication date
4 June 2008
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published in
Journal of Neuroscience
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volume
28
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issue
23
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page(s)
6030-6
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describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2586000/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b
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PubMed Central
reference URL
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19 March 2017
BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production
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PubMed Central
reference URL
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19 March 2017
The familial dementia BRI2 gene binds the Alzheimer gene amyloid-beta precursor protein and inhibits amyloid-beta production
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PubMed Central
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19 March 2017
Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin
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19 March 2017
A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred
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19 March 2017
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia
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A stop-codon mutation in the BRI gene associated with familial British dementia
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19 March 2017
Sequence, genomic structure and tissue expression of Human BRI3, a member of the BRI gene family
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19 March 2017
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
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Genetic alterations of the BRI2 gene: familial British and Danish dementias
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Adeno-associated virus vectors serotyped with AAV8 capsid are more efficient than AAV-1 or -2 serotypes for widespread gene delivery to the neonatal mouse brain
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27 September 2017
Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model
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27 September 2017
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice
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27 September 2017
Axonal transport of British and Danish amyloid peptides via secretory vesicles
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27 September 2017
Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain
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27 September 2017
Intraventricular brain injection of adeno-associated virus type 1 (AAV1) in neonatal mice results in complementary patterns of neuronal transduction to AAV2 and total long-term correction of storage lesions in the brains of beta-glucuronidase-defici
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Abeta40 inhibits amyloid deposition in vivo.
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PubMed Central
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29 November 2018
Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice.
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29 November 2018
Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme.
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29 November 2018
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29 November 2018
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29 November 2018
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29 November 2018
Amyloid-beta protofibrils differ from amyloid-beta aggregates induced in dilute hexafluoroisopropanol in stability and morphology.
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29 November 2018
Beta-amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH.
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29 November 2018
Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition.
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29 November 2018
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.
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29 November 2018
Identifiers
DOI
10.1523/JNEUROSCI.0891-08.2008
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PMC publication ID
2586000
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PubMed publication ID
18524908
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ResearchGate publication ID
51401207
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