(Q24322097)

English

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine

scientific article

In more languages

Statements

scholarly article

0 references

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine (English)

0 references

0 references

cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)

1 reference

GOA release 2020-03-11

aromatase activity

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

Vijayalakshmi Ravindranath

6

object named as

Vijayalakshmi Ravindranath

0 references

author name string

Harish V Pai

1

0 references

Reddy P Kommaddi

2

0 references

Shankar J Chinta

3

0 references

Toshiyuki Mori

4

0 references

Michael R Boyd

5

0 references

language of work or name

0 references

publication date

25 June 2004

0 references

Journal of Biological Chemistry

0 references

279

0 references

26

0 references

27383-9

0 references

The metabolism of xenobiotics by certain extrahepatic organs and its relation to toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Xenobiotic metabolism in brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Cytochrome P450 in the brain; a review.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Rat brain cytochromes P-450: catalytic, immunochemical properties and inducibility of multiple forms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Xenobiotic metabolism in human brain--presence of cytochrome P-450 and associated mono-oxygenases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Cytochrome P4502E (CYP2E) in brain: constitutive expression, induction by ethanol and localization by fluorescence in situ hybridization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Brain mitochondrial cytochromes P450: xenobiotic metabolism, presence of multiple forms and their selective inducibility.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Effect of ethanol on cytochrome P450 in the rat brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

A novel P450 expressed at the high level in rat brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Regulation of CYP3A9 gene expression by estrogen and catalytic studies using cytochrome P450 3A9 expressed in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Differential metabolism of alprazolam by liver and brain cytochrome (P4503A) to pharmacologically active metabolite

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Characterization of a phenobarbital-inducible cytochrome P-450, NADPH-cytochrome P-450 reductase and reconstituted cytochrome P-450 mono-oxygenase system from rat brain. Evidence for constitutive presence in rat and human brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Human cytochromes P450: problems and prospects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Oxidation of reduced haloperidol to haloperidol: involvement of human P450IID6 (sparteine/debrisoquine monooxygenase).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Cloning, sequencing and tissue distribution of rat flavin-containing monooxygenase 4: two different forms are produced by tissue-specific alternative splicing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Alternative RNA splicing in the nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Regional distribution of individual forms of cytochrome P450 mRNA in normal adult human brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Identification of the convulsant opiate thebaine in mammalian brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Are poor metabolisers of sparteine/debrisoquine less pain tolerant than extensive metabolisers?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Morphine formation from codeine in rat brain: a possible mechanism of codeine analgesia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Cellular actions of opioids and other analgesics: implications for synergism in pain relief

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Microsomal cytochrome P450 in human brain regions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Biochemical mechanisms in chemical-induced lung injury: roles of metabolic activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Cytochrome P -450 activities in human and rat brain microsomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

21 January 2018

Further characterization of rat brain flavin-containing monooxygenase. Metabolism of imipramine to its N-oxide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of cytochrome P450 in the central nervous system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

7 January 2021

based on heuristic

inferred from DOI database lookup

The pharmacogenetics of codeine hypoalgesia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

7 January 2021

based on heuristic

inferred from DOI database lookup

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

7 January 2021

based on heuristic

inferred from DOI database lookup

Variable cytochrome P450 2D6 expression and metabolism of codeine and other opioid prodrugs: implications for the Australian anaesthetist.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402337200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M402337200

0 references

PubMed publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q24322097&oldid=1512294147"