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The kinase TNIK is an essential activator of Wnt target genes
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title
The kinase TNIK is an essential activator of Wnt target genes
(English)
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main subject
TRAF2 and NCK interacting kinase
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stated in
GOA release 2020-03-11
author
Hans Clevers
series ordinal
8
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Shabaz Mohammed
object named as
Shabaz Mohammed
series ordinal
6
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Albert J.R. Heck
object named as
Albert J Heck
series ordinal
7
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Tokameh Mahmoudi
series ordinal
1
object named as
Tokameh Mahmoudi
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author name string
Vivian S W Li
series ordinal
2
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Ser Sue Ng
series ordinal
3
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Nadia Taouatas
series ordinal
4
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Robert G J Vries
series ordinal
5
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language of work or name
English
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publication date
4 November 2009
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published in
The EMBO Journal
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volume
28
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page(s)
3329-40
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issue
21
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cites work
The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton
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stated in
PubMed Central
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19 March 2017
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
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19 March 2017
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex
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PubMed Central
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19 March 2017
The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation
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PubMed Central
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19 March 2017
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling
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PubMed Central
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19 March 2017
TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton
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PubMed Central
reference URL
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19 March 2017
Identification of c-MYC as a target of the APC pathway
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PubMed Central
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19 March 2017
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
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PubMed Central
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19 March 2017
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
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PubMed Central
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19 March 2017
Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
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PubMed Central
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19 March 2017
Wnt/beta-catenin signaling in development and disease
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PubMed Central
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19 March 2017
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
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PubMed Central
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19 March 2017
Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels
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19 March 2017
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19 March 2017
Functional interaction of beta-catenin with the transcription factor LEF-1
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PubMed Central
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19 March 2017
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
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PubMed Central
reference URL
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19 March 2017
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
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PubMed Central
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19 March 2017
The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
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PubMed Central
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19 March 2017
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
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PubMed Central
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19 March 2017
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
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19 March 2017
Linking colorectal cancer to Wnt signaling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776109
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7 April 2017
Beta-catenin hits chromatin: regulation of Wnt target gene activation
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PubMed Central
reference URL
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27 September 2017
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
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27 September 2017
Highly robust, automated, and sensitive online TiO2-based phosphoproteomics applied to study endogenous phosphorylation in Drosophila melanogaster.
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27 September 2017
The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes
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27 September 2017
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
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PubMed Central
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27 September 2017
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors
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reference URL
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27 September 2017
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
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PubMed Central
reference URL
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27 September 2017
Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2776109
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27 September 2017
Differential localization by in situ hybridization of distinct keratin mRNA species during intestinal epithelial cell development and differentiation.
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2009.285
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21 January 2018
The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2009.285
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/EMBOJ.2009.285
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3429320
OpenCitations bibliographic resource ID
3429320
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3429320
PMCID
2776109
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3429320
PubMed ID
19816403
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3429320
ResearchGate publication ID
26882311
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