(Q24324784)

lysine-acetylated histone binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Jon R Wilson

5

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author name string

Stacey M Southall

1

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Poon-Sheng Wong

2

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Zain Odho

3

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S Mark Roe

MLL: how complex does it get?

4

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language of work or name

English

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publication date

30 January 2009

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published in

Molecular Cell

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volume

33

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page(s)

181-91

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issue

2

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cites work

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Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

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Genomic maps and comparative analysis of histone modifications in human and mouse

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WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development

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Genome-wide map of nucleosome acetylation and methylation in yeast

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Chromatin modifications and their function

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A chromatin landmark and transcription initiation at most promoters in human cells

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Structural characterization of Set1 RNA recognition motifs and their role in histone H3 lysine 4 methylation.

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Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression.

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MLL: a histone methyltransferase disrupted in leukemia

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SET domains and histone methylation.

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Crystal structure and functional analysis of the histone methyltransferase SET7/9

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MLL targets SET domain methyltransferase activity to Hox gene promoters

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Structural basis for the product specificity of histone lysine methyltransferases

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6 Structure of SET domain protein lysine methyltransferases

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Regulation of chromatin structure by site-specific histone H3 methyltransferases

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Altered Hox expression and segmental identity in Mll-mutant mice

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Structure and catalytic mechanism of the human histone methyltransferase SET7/9

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Double chromodomains cooperate to recognize the methylated histone H3 tail

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The complex language of chromatin regulation during transcription

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Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

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Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

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A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3

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Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT

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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

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Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes

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Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

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7 January 2021

Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains

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Structural basis for molecular recognition and presentation of histone H3 by WDR5

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The MLL recombinome of acute leukemias

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Global and Hox-specific roles for the MLL1 methyltransferase

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Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

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The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas

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COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression

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7 January 2021

Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide

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7 January 2021

Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation

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Molecular Basis of Histone H3K4me3 Recognition by ING4

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WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket

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7 January 2021

The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment

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7 January 2021

Specificity and mechanism of the histone methyltransferase Pr-Set7.

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Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase

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7 January 2021

PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation

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The CCP4 suite: programs for protein crystallography

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Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

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7 January 2021

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

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7 January 2021

The SET-domain protein superfamily: protein lysine methyltransferases

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7 January 2021

Dynamic regulation of effector protein binding to histone modifications: the biology of HP1 switching.

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Biphasic MLL takes helm at cell cycle control: implications in human mixed lineage leukemia

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7 January 2021