(Q24339384)

GOA release 2020-03-11

Unc-51 like kinase 3

1 reference

GOA release 2020-03-11

protein kinase binding

1 reference

GOA release 2020-03-11

4

Lauri Peil

0 references

author name string

Alla Maloverjan

1

0 references

Marko Piirsoo

2

0 references

Lagle Kasak

3

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Torben Østerlund

5

0 references

Priit Kogerman

Journal of Biological Chemistry

6

0 references

language of work or name

English

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publication date

24 September 2010

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published in

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volume

285

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issue

39

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page(s)

30079-90

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cites work

Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Identification of the gene transcription repressor domain of Gli3

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Gli proteins and the control of spinal-cord patterning

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Gli regulation by the opposing activities of fused and suppressor of fused

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

A possible role of mouse Fused (STK36) in Hedgehog signaling and Gli transcription factor regulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Tissue repair and stem cell renewal in carcinogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Gli1 can rescue the in vivo function of Gli2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Hedgehog signaling in animal development: paradigms and principles

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Mutations affecting segment number and polarity in Drosophila

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

The Gli code: an information nexus regulating cell fate, stemness and cancer.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Communicating with Hedgehogs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Functional domains of fused, a serine-threonine kinase required for signaling in Drosophila

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Phosphorylation of the fused protein kinase in response to signaling from hedgehog

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2943318

Eyes absent, a key repressor of polar cell fate during Drosophila oogenesis

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Genetic dissection of the Drosophila Cubitus interruptus signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Identification of a tetrameric hedgehog signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Modulation of Hedgehog target gene expression by the Fused serine-threonine kinase in wing imaginal discs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.133991

Sample preparation by SDS/PAGE and in-gel digestion

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20643644

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20643644