(Q24528153)

3

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author name string

Susan P Yates

1

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Patricia L Taylor

2

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Jie Zhang

5

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Gregers R Andersen

6

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A Rod Merrill

Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling

7

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language of work or name

English

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publication date

1 February 2005

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published in

Biochemical Journal

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volume

385

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issue

Pt 3

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page(s)

667-75

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cites work

1 reference

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Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken

24 March 2017

1 reference

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Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation

24 March 2017

1 reference

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Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

The crystal structure of Pseudomonas aeruginosa exotoxin domain III with nicotinamide and AMP: conformational differences with the intact exotoxin

24 March 2017

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

24 March 2017

1 reference

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

24 March 2017

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

24 March 2017

1 reference

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The ARTT motif and a unified structural understanding of substrate recognition in ADP-ribosylating bacterial toxins and eukaryotic ADP-ribosyltransferases.

24 March 2017

1 reference

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Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited

27 September 2017

1 reference

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Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke

27 September 2017

1 reference

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Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist

27 September 2017

1 reference

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Cell-to-cell signaling and Pseudomonas aeruginosa infections

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Active site mutations of Pseudomonas aeruginosa exotoxin A. Analysis of the His440 residue

27 September 2017

1 reference

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Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

27 September 2017

1 reference

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Translational dynamics. Interactions between the translational factors, tRNA and ribosomes during eukaryotic protein synthesis

27 September 2017

1 reference

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69 Toxin Inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A

27 September 2017

1 reference

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Mono(ADP-ribosyl)transferases and related enzymes in animal tissues. Emerging gene families

27 September 2017

1 reference

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Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Unusual conformation of nicotinamide adenine dinucleotide (NAD) bound to diphtheria toxin: a comparison with NAD bound to the oxidoreductase enzymes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Mutations in the elongation factor 2 gene which confer resistance to diphtheria toxin and Pseudomonas exotoxin A. Genetic and biochemical analyses

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Receptor-mediated internalization of Pseudomonas toxin by mouse fibroblasts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. Part 4: biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Design and synthesis of poly ADP-ribose polymerase-1 inhibitors. 2. Biological evaluation of aza-5[H]-phenanthridin-6-ones as potent, aqueous-soluble compounds for the treatment of ischemic injuries.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Characterization of competitive inhibitors for the transferase activity of Pseudomonas aeruginosa exotoxin A.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Novel tricyclic poly(ADP-ribose) polymerase-1 inhibitors with potent anticancer chemopotentiating activity: design, synthesis, and X-ray cocrystal structure

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Purification and crystallization of the yeast elongation factor eEF2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Poly(ADP-Ribose) polymerase inhibition reduces reperfusion injury after heart transplantation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

A catalytic loop within Pseudomonas aeruginosa exotoxin A modulates its transferase activity

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Synthesis of substituted 5[H]phenanthridin-6-ones as potent poly(ADP-ribose)polymerase-1 (PARP1) inhibitors.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

Application of a fluorometric assay for characterization of the catalytic competency of a domain III fragment of Pseudomonas aeruginosa exotoxin A.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

PRODRG, a program for generating molecular topologies and unique molecular descriptors from coordinates of small molecules.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1134741

GPI 6150 prevents H(2)O(2) cytotoxicity by inhibiting poly(ADP-ribose) polymerase

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15458385

12 December 2020

inferred from PubMed ID database lookup

Design and synthesis of poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors. Part 3: In vitro evaluation of 1,3,4,5-tetrahydro-benzo[c][1,6]- and [c][1,7]-naphthyridin-6-ones

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15458385

12 December 2020

inferred from PubMed ID database lookup

Pseudomonas aeruginosa exotoxin A: effects of mutating tyrosine-470 and tyrosine-481 to phenylalanine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15458385

12 December 2020

inferred from PubMed ID database lookup

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20041480

7 January 2021

inferred from DOI database lookup

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20041480

7 January 2021

inferred from DOI database lookup

MOLREP: an Automated Program for Molecular Replacement

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20041480

7 January 2021