(Q24556671)

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Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design

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scholarly article

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Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design (English)

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Malcolm Walkinshaw

8

object named as

Malcolm D Walkinshaw

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Peter M. Fischer

object named as

Peter M Fischer

7

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object named as

David P Lane

6

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author name string

George Kontopidis

1

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Su-Ying Wu

2

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Daniella I Zheleva

3

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Paul Taylor

4

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Campbell McInnes

5

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language of work or name

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publication date

8 February 2005

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Proceedings of the National Academy of Sciences of the United States of America

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102

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6

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1871-6

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Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

D-type cyclin-binding regions of proliferating cell nuclear antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

24 March 2017

Peptidomimetic design of CDK inhibitors targeting the recruitment site of the cyclin subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

Cellular delivery of impermeable effector molecules in the form of conjugates with peptides capable of mediating membrane translocation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

Proliferating cell nuclear antigen (PCNA): ringmaster of the genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

Involvement of the interaction between p21 and proliferating cell nuclear antigen for the maintenance of G2/M arrest after DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

The puzzle of PCNA's many partners

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

Inhibition of gastric cancer cell proliferation by antisense oligonucleotides targeting the messenger RNA encoding proliferating cell nuclear antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

27 September 2017

Reversible phosphorylation at the C-terminal regulatory domain of p21(Waf1/Cip1) modulates proliferating cell nuclear antigen binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

30 May 2018

p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=548533

30 May 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406540102

21 January 2018

MOLREP: an Automated Program for Molecular Replacement

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0406540102

21 January 2018

A quantitative study of the in vitro binding of the C-terminal domain of p21 to PCNA: affinity, stoichiometry, and thermodynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly potent p21(WAF1)-derived peptide inhibitors of CDK-mediated pRb phosphorylation: delineation and structural insight into their interactions with cyclin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Who binds wins: Competition for PCNA rings out cell-cycle changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense oligonucleotides to proliferating cell nuclear antigen and Ki-67 inhibit human mesangial cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of rheumatoid synovial fibroblast proliferation by antisense oligonucleotides targeting proliferating cell nuclear antigen messenger RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PCNA, a multifunctional ring on DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15681588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0406540102

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2005PNAS..102.1871K

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PMC publication ID

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PubMed publication ID

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ResearchGate publication ID

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