(Q24557569)

English

Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades

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Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades (English)

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author name string

Geng-Xian Shi

1

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Douglas A Andres

2

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language of work or name

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publication date

January 2005

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Molecular and Cellular Biology

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25

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2

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830-46

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R-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade.

1 reference

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Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway

1 reference

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Neurotrophins: roles in neuronal development and function

1 reference

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Biochemical characterization of the Ras-related GTPases Rit and Rin

1 reference

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A simplified system for generating recombinant adenoviruses

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1 reference

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1 reference

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24 March 2017

Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins

1 reference

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1 reference

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24 March 2017

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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24 March 2017

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1 reference

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24 March 2017

Rit promotes MEK-independent neurite branching in human neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

24 March 2017

Extracellular signal regulated kinase (ERK)/mitogen activated protein kinase (MAPK)-independent functions of Raf kinases

1 reference

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24 March 2017

A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

24 March 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

24 March 2017

Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

24 March 2017

The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

24 March 2017

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

24 March 2017

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

24 March 2017

Small GTP-binding proteins

1 reference

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7 April 2017

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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7 April 2017

ras oncogenes in human cancer: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

7 April 2017

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

7 April 2017

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

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Neurotrophins and their receptors: a convergence point for many signalling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

1 reference

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7 April 2017

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

7 April 2017

Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

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1 reference

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27 September 2017

Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

The role of Rap1 in integrin-mediated cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Neurotrophic factors and axonal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Signaling the pathway to regeneration

1 reference

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1 reference

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27 September 2017

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1 reference

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1 reference

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27 September 2017

Activation of the Ral and phosphatidylinositol 3' kinase signaling pathways by the ras-related protein TC21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Analysis of R-Ras signalling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Use of kinase inhibitors to dissect signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

The Ras branch of small GTPases: Ras family members don't fall far from the tree

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Oncogenic activation of human R-ras by point mutations analogous to those of prototype H-ras oncogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

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Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

Determination of guanine nucleotides bound to Ras in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

27 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

A system for characterizing cellular and molecular events in programmed neuronal cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

Expression of raf family proto-oncogenes in normal mouse tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

30 May 2018

The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

28 November 2018

Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

28 November 2018

Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

28 November 2018

SB203580 promotes EGF-stimulated early morphological differentiation in PC12 cell through activating ERK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

28 November 2018

The myotonic dystrophy kinase-related Cdc42-binding kinase is involved in the regulation of neurite outgrowth in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

28 November 2018

Increasing complexity of Ras signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=543422

28 November 2018

Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of neurite extension and survival in pheochromocytoma cells by the Rit GTPase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of neurite outgrowth by MAP kinase in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium influx induces neurite growth through a Src-Ras signaling cassette

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitogen activated protein kinase inhibition by PD98059 blocks nerve growth factor stimulated axonal outgrowth from adult mouse dorsal root ganglia in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15632082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1128%2FMCB.25.2.830-846.2005

7 January 2021

based on heuristic

inferred from DOI database lookup

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