(Q24595571)

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The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex

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scholarly article

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The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex (English)

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5

object named as

Caryn Lerman

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Dorothy Hatsukami

3

object named as

Dorothy K Hatsukami

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4

object named as

Gary E Swan

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Rachel F Tyndale

7

object named as

Rachel F Tyndale

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author name string

Andy Z X Zhu

1

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Caroline C Renner

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Neal L Benowitz

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language of work or name

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publication date

April 2013

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Cancer Epidemiology, Biomarkers & Prevention

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22

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4

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708-18

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Racial differences in serum cotinine levels among smokers in the Coronary Artery Risk Development in (Young) Adults study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

24 March 2017

Polymorphisms of CYP2A6 and its practical consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

24 March 2017

Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Exposure to nicotine and carcinogens among Southwestern Alaskan Native cigarette smokers and smokeless tobacco users

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Exposure and kinetics of polycyclic aromatic hydrocarbons (PAHs) in cigarette smokers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Urine menthol as a biomarker of mentholated cigarette smoking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Genetic variation in nicotine metabolism predicts the efficacy of extended-duration transdermal nicotine therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Utility and relationships of biomarkers of smoking in African-American light smokers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid chromatography-tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Sex-related differences in serum cotinine concentrations in daily cigarette smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

A novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Genetic variability in CYP2A6 and the pharmacokinetics of nicotine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Human CYP2A6 is induced by estrogen via estrogen receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Determination of phenolic metabolites of polycyclic aromatic hydrocarbons in human urine as their pentafluorobenzyl ether derivatives using liquid chromatography-tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

High exposure to polycyclic aromatic hydrocarbons may contribute to high risk of esophageal cancer in northeastern Iran.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Metabolism and disposition kinetics of nicotine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Pharmacogenetics of nicotine metabolism in twins: methods and procedures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Tobacco carcinogens, their biomarkers and tobacco-induced cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Accelerated metabolism of nicotine and cotinine in pregnant smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Cotinine as a biomarker of environmental tobacco smoke exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

27 September 2017

Three haplotypes associated with CYP2A6 phenotypes in Caucasians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

30 May 2018

Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

30 May 2018

Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

Hepatic CYP2B6 is altered by genetic, physiologic, and environmental factors but plays little role in nicotine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

Ethnic variation in CYP2A6*7, CYP2A6*8 and CYP2A6*10 as assessed with a novel haplotyping method.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

A novel polymorphism of human CYP2A6 gene CYP2A6*17 has an amino acid substitution (V365M) that decreases enzymatic activity in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

An in vivo pilot study characterizing the new CYP2A6*7, *8, and *10 alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3617060

28 November 2018

Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum cotinine level as predictor of lung cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of human cytochrome P4502A6 in C-oxidation of nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cotinine disposition and effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3',3'-d2 in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine metabolism and intake in black and white smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course of nicotine and cotinine incorporation into samples of nonsmokers' beard hair following a single dose of nicotine polacrilex

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is 24h nicotine equivalents a surrogate for smoke exposure based on its relationship with other biomarkers of exposure?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23371292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1055-9965.EPI-12-1234-T

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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