(Q24602889)

2

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B Cornett

3

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K H Downing

4

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E Nogales

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

24 April 2001

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published in

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volume

98

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issue

9

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page(s)

5312-6

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cites work

Structure of the alpha beta tubulin dimer by electron crystallography

1 reference

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High-resolution model of the microtubule

7 April 2017

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A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

7 April 2017

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Conformation of microtubule-bound paclitaxel determined by fluorescence spectroscopy and REDOR NMR.

27 September 2017

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A common pharmacophore for cytotoxic natural products that stabilize microtubules

27 September 2017

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Effect of 2'-OH acetylation on the bioactivity and conformation of 7-O-[N-(4'-fluoresceincarbonyl)-L-alanyl]taxol. A NMR-fluorescence microscopy study.

27 September 2017

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Conformation of a water-soluble derivative of taxol in water by 2D-NMR spectroscopy

27 September 2017

1 reference

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Crystal and molecular structure of paclitaxel (taxol).

27 September 2017

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Taxol binds to polymerized tubulin in vitro

27 September 2017

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Synthesis and structure-activity relationships of new antitumor taxoids. Effects of cyclohexyl substitution at the C-3' and/or C-2 of taxotere (docetaxel).

27 September 2017

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Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

27 September 2017

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3'-(p-azidobenzamido)taxol photolabels the N-terminal 31 amino acids of beta-tubulin

30 May 2018

1 reference

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Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin

30 May 2018

1 reference

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Relationships between the structure of taxol analogs and their antimitotic activity

30 May 2018

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Biologically active taxol analogs with deleted A-ring side chain substituents and variable C-2' configurations

30 May 2018

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Direct photoaffinity labeling of tubulin with taxol

30 May 2018

1 reference

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Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: reversibility, ligand stoichiometry, and competition

30 May 2018

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Predominant labeling of beta- over alpha-tubulin from porcine brain by a photoactivatable taxoid derivative

21 January 2018

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[3H](azidophenyl)ureido taxoid photolabels peptide amino acids 281-304 of alpha-tubulin

21 January 2018

1 reference

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A fast flexible docking method using an incremental construction algorithm.

21 January 2018

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The oxetane ring in taxol.

21 January 2018

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Unexpectedly Facile Hydrolysis of the 2-Benzoate Group of Taxol and Syntheses of Analogs with Increased Activities

21 January 2018

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A Common Pharmacophore for Taxol and the Epothilones Based on the Biological Activity of a Taxane Molecule Lacking a C-13 Side Chain†

21 January 2018

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NMR and molecular modeling study of the conformations of taxol and of its side chain methylester in aqueous and non-aqueous solution

21 January 2018

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Characterization of the Taxol Binding Site on the Microtubule

21 January 2018

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Ab InitioConformational Study of the Phenylisoserine Side Chain of Paclitaxel

21 January 2018

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12 December 2020

Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "hydrophobic collapse" conformation

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12 December 2020

Synthesis of a photoaffinity taxol analogue and its use in labeling tubulin

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12 December 2020

The effect of the aromatic rings of taxol on biological activity and solution conformation: synthesis and evaluation of saturated taxol and taxotere analogues

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12 December 2020

Crystal structure of 2-debenzoyl, 2-acetoxy paclitaxel (Taxol): conformation of the paclitaxel side-chain

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12 December 2020

NMR and molecular modeling study of the conformations of taxol 2'-acetate in chloroform and aqueous dimethyl sulfoxide solutions

1 reference

12 December 2020

Chemistry and Biology of Taxol

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1073/PNAS.051309398

1 reference

ADS bibcode

2001PNAS...98.5312S

0 references

1 reference

1 reference

PubMed publication ID

11309480

1 reference