(Q24608574)

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Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target

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Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target (English)

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prostate cancer

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18

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Francesca Demichelis

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Francesca Demichelis

16

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Mark A Rubin

15

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Arul Chinnaiyan

21

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Arul M Chinnaiyan

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1

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Colin C Collins

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Himisha Beltran

17

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Himisha Beltran

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Christopher A Maher

20

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Christopher A Maher

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author name string

Stanislav V Volik

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Anna V Lapuk

3

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Yuwei Wang

4

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Peter W Gout

5

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Chunxiao Wu

6

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Hui Xue

7

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Hongwei Cheng

8

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Anne Haegert

9

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Robert H Bell

10

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Sonal Brahmbhatt

11

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Shawn Anderson

12

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Ladan Fazli

13

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Antonio Hurtado-Coll

14

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Marco Marra

19

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Martin Gleave

22

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Joseph R Bertino

23

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Martin Lubin

24

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Yuzhuo Wang

25

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language of work or name

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publication date

March 2012

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Molecular Cancer Therapeutics

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11

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3

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775-83

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Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

7 April 2017

Mapping short DNA sequencing reads and calling variants using mapping quality scores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

7 April 2017

Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

7 April 2017

Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

7 April 2017

Integrative genomic profiling of human prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

7 April 2017

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

7 April 2017

Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Advances in whole genome sequencing technology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Use of irinotecan for treatment of small cell carcinoma of the prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Insulin receptor expression by human prostate cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

ASAP1, a gene at 8q24, is associated with prostate cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

The mighty mouse: genetically engineered mouse models in cancer drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Establishment in severe combined immunodeficiency mice of subrenal capsule xenografts and transplantable tumor lines from a variety of primary human lung cancers: potential models for studying tumor progression-related changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Brain metastasis from prostate small cell carcinoma: not to be neglected

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Results of a phase II study with doxorubicin, etoposide, and cisplatin in patients with fully characterized small-cell carcinoma of the prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Diagnosing and treating small-cell carcinomas of prostatic origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Neuroendocrine differentiation in prostatic carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Histologic variants of adenocarcinoma and other carcinomas of prostate: pathologic criteria and clinical significance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Small cell carcinoma of the bladder and prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Neuroendocrine differentiation in carcinoma of the prostate. Diagnostic, prognostic, and therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Small cell carcinoma of prostate: Effectiveness of hormonal versus chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

27 September 2017

Development and characterization of efficient xenograft models for benign and malignant human prostate tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

30 May 2018

Neuroendocrine cells in benign and malignant prostate tissue: morphogenesis, proliferation, and androgen receptor status.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

30 May 2018

CDKN2A and MTAP deletions in peritoneal mesotheliomas are correlated with loss of p16 protein expression and poor survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

28 November 2018

Homozygous deletion of MTAP gene as a poor prognosticator in gastrointestinal stromal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

28 November 2018

A phase II multicenter study of L-alanosine, a potent inhibitor of adenine biosynthesis, in patients with MTAP-deficient cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3691697

28 November 2018

Tumor growth inhibition by olaparib in BRCA2 germline-mutated patient-derived ovarian cancer tissue xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22252602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progression of prostate cancer to neuroendocrine cell tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22252602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroendocrine differentiated small cell carcinoma presenting as recurrent prostate cancer after androgen deprivation therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22252602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphology and therapeutic strategies for neuroendocrine tumors of the genitourinary tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/22252602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CDKN2A tumor-suppressor locus--a tale of two proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22252602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of subrenal capsule xenografts of primary human ovarian tumors in SCID mice: potential models

1 reference

https://pubmed.ncbi.nlm.nih.gov/22252602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1535-7163.MCT-11-0826

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