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Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
title
Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
main subject
prostate cancer
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inferred from title
author
Eva Slabáková
series ordinal
2
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stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Jan Bouchal
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Milan Král
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5
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Miroslav Machala
series ordinal
7
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Alois Kozubík
series ordinal
8
object named as
Alois Kozubík
1 reference
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
author name string
Zuzana Pernicová
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Gvantsa Kharaishvili
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Zuzana Kunická
series ordinal
6
1 reference
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Karel Souček
series ordinal
9
1 reference
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
language of work or name
English
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publication date
1 June 2011
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Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
published in
Neoplasia
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PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
volume
13
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
issue
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
page(s)
526-536
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
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Europe PubMed Central
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11 June 2022
reference URL
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based on heuristic
inferred from PubMed Central ID database lookup
cites work
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Neuroendocrine differentiation in prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
The epithelial-mesenchymal transition: new insights in signaling, development, and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
The F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Regulation of the cell cycle by SCF-type ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
The senescence-associated secretory phenotype: the dark side of tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Cellular senescence: when bad things happen to good cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
The development of androgen-independent prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
7 April 2017
An update on androgen deprivation therapy for prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Biomarkers for epithelial-mesenchymal transitions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
EMT: when epithelial cells decide to become mesenchymal-like cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Hallmarks for senescence in carcinogenesis: novel signaling players.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Senescence-induced alterations of laminin chain expression modulate tumorigenicity of prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
An AR-Skp2 pathway for proliferation of androgen-dependent prostate-cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Clinical implications of neuroendocrine differentiation in prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Quantitative assay of senescence-associated beta-galactosidase activity in mammalian cell extracts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Senescence and immortalization: role of telomeres and telomerase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Molecular characterization of human prostate carcinoma cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Hormone-refractory prostate cancer: a multi-step and multi-event process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Senescence and cytoskeleton: overproduction of vimentin induces senescent-like morphology in human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
27 September 2017
Androgen deprivation induces human prostate epithelial neuroendocrine differentiation of androgen-sensitive LNCaP cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
30 May 2018
Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
30 May 2018
Evidence for a critical telomere length in senescent human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
30 May 2018
Characterization of epithelial senescence by serial analysis of gene expression: identification of genes potentially involved in prostate cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
28 November 2018
Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3114246
retrieved
28 November 2018
Inverse relationship between Skp2 ubiquitin ligase and the cyclin dependent kinase inhibitor p27Kip1 in prostate cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21677876
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Prostate cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21677876
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1593/NEO.11182
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
Fatcat ID
release_cotokhd25zfnfeskcnszhujkce
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/cotokhd25zfnfeskcnszhujkce
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3114246
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
PubMed publication ID
21677876
1 reference
stated in
Europe PubMed Central
PMC publication ID
3114246
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21677876%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
ResearchGate publication ID
51223607
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