(Q24618100)

2

0 references

Anne Fassl

3

0 references

Anika Krämer

4

0 references

Ina Oehme

5

0 references

Hans-Walter Zentgraf

6

0 references

Martina Keith

7

0 references

Wilfried Roth

Journal of Biological Chemistry

8

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language of work or name

English

0 references

publication date

9 July 2010

0 references

published in

0 references

volume

285

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issue

28

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page(s)

21644-54

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cites work

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Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

7 April 2017

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Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action

7 April 2017

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Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation

7 April 2017

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7 April 2017

The Hallmarks of Cancer

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

7 April 2017

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

7 April 2017

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Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function

7 April 2017

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

7 April 2017

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PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

7 April 2017

1 reference

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Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

7 April 2017

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Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro

7 April 2017

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A factor preventing the major head protein of bacteriophage T4 from random aggregation

7 April 2017

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

7 April 2017

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

7 April 2017

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JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

7 April 2017

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PTEN loss promotes mitochondrially dependent type II Fas-induced apoptosis via PEA-15.

7 April 2017

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Regulation of HMGB1 release by autophagy

27 September 2017

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PEA-15 induces autophagy in human ovarian cancer cells and is associated with prolonged overall survival

27 September 2017

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ERK and JNK mediate TNFalpha-induced p53 activation in apoptotic and autophagic L929 cell death

27 September 2017

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Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

27 September 2017

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Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation

27 September 2017

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The PEA-15/PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK/MAP kinase pathway.

27 September 2017

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Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway

27 September 2017

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Autophagy and cell death.

27 September 2017

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Methods for monitoring autophagy from yeast to human

27 September 2017

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c-Jun NH(2)-terminal kinase 2alpha2 promotes the tumorigenicity of human glioblastoma cells

27 September 2017

1 reference

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Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase C delta-dependent mechanism

27 September 2017

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Antitumor effect of E1A in ovarian cancer by cytoplasmic sequestration of activated ERK by PEA15.

27 September 2017

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Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.

27 September 2017

1 reference

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Autophagy: dual roles in life and death?

27 September 2017

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Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

PEA-15 modulates TNFalpha intracellular signaling in astrocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Inhibition of DNA repair for sensitizing resistant glioma cells to temozolomide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

The multifunctional protein PEA-15 is involved in the control of apoptosis and cell cycle in astrocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

C-Jun NH(2)-terminal kinase mediates proliferation and tumor growth of human prostate carcinoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Pten signaling in gliomas

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Molecular profiling of transformed and metastatic murine squamous carcinoma cells by differential display and cDNA microarray reveals altered expression of multiple genes related to growth, apoptosis, angiogenesis, and the NF-kappaB signal pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Phorbol ester-induced amino-terminal phosphorylation of human JUN but not JUNB regulates transcriptional activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Allele losses on chromosome 17 in human epithelial ovarian carcinoma

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Allele loss from chromosome 17 in ovarian cancer.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

C-terminal splicing of NTPDase2 provides distinctive catalytic properties, cellular distribution and enzyme regulation

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.096628

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.096628

Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK, and P38 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.096628

p120 GAP modulates Ras activation of Jun kinases and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.096628

The induction of autophagy by gamma-radiation contributes to the radioresistance of glioma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.096628

PTEN mutations in gliomas and glioneuronal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.096628

Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898427

Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms

28 November 2018

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12 December 2020

Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM region on 17q21.3 often and commonly deleted in tumors

1 reference

12 December 2020

Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer

1 reference

12 December 2020

Constitutive activation of c-Jun N-terminal kinase correlates with histologic grade and EGFR expression in diffuse gliomas

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.096628

1 reference

5102145

5102145

1 reference

1 reference

1 reference