(Q24647033)

1

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Cristina Pop

2

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Fiona L Scott

3

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Paul Swartz

5

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Carla Mattos

6

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Guy S Salvesen

7

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A Clay Clark

Creative Commons Attribution-NonCommercial 2.5 Generic

8

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language of work or name

English

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publication date

15 December 2009

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published in

Biochemical Journal

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volume

424

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issue

3

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page(s)

335-45

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copyright license

start time

25 July 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

An Allosteric Circuit in Caspase-1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Structural basis for the activation of human procaspase-7

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Dimer formation drives the activation of the cell death protease caspase 9

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Coot: model-building tools for molecular graphics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

7 April 2017

Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Mechanisms of caspase activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Multiple solvent crystal structures of ribonuclease A: an assessment of the method

7 April 2017

1 reference

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

22 April 2017

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Comparison of simple potential functions for simulating liquid water

22 April 2017

1 reference

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

22 April 2017

1 reference

Use of non-crystallographic symmetry in protein structure refinement

22 April 2017

1 reference

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Quantitative analysis of pathways controlling extrinsic apoptosis in single cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Targeting cell death in tumors by activating caspases

27 September 2017

1 reference

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Apoptosis and necrosis: detection, discrimination and phagocytosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Role of loop bundle hydrogen bonds in the maturation and activity of (Pro)caspase-3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

The protein structures that shape caspase activity, specificity, activation and inhibition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Discovery of an allosteric site in the caspases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Caspase activation, inhibition, and reactivation: a mechanistic view

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

The role of Bcl-2 family members in tumorigenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Hodgkin's lymphoma: biology and treatment strategies for primary, refractory, and relapsed disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Mutations in the Procaspase-3 Dimer Interface Affect the Activity of the Zymogen

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

An Uncleavable Procaspase-3 Mutant Has a Lower Catalytic Efficiency but an Active Site Similar to That of Mature Caspase-3

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Mechanism-based inactivation of caspases by the apoptotic suppressor p35.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Ionic interactions near the loop L4 are important for maintaining the active-site environment and the dimer stability of (pro)caspase 3.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Pro-caspase-3 is a major physiologic target of caspase-8.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Role of proteolysis in caspase-8 activation and stabilization

30 May 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

Expression of apoptosome pathway-related transcripts in non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

Analysis of apoptosis in cell-free systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

Expression of caspase-3 and -7 does not correlate with the extent of apoptosis in primary breast carcinomas

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2805924

Achilles' heel of cancer?

28 November 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20090825

Quantification of active caspase 3 in apoptotic cells

21 January 2018

1 reference

12 December 2020

Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia

1 reference

12 December 2020

Interdimer processing and linearity of procaspase-3 activation. A unifying mechanism for the activation of initiator and effector caspases

1 reference

12 December 2020

Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20090825

1 reference

1 reference

1 reference

PubMed publication ID

19788411

1 reference