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Caspase activation, inhibition, and reactivation: a mechanistic view
scientific article published in August 2004
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scholarly article
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Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
review article
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stated in
Europe PubMed Central
title
Caspase activation, inhibition, and reactivation: a mechanistic view
(English)
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stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
author name string
Yigong Shi
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
publication date
1 August 2004
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stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
published in
Protein Science
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stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
volume
13
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stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
page(s)
1979-1987
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stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
issue
8
1 reference
stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
cites work
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
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11 July 2018
Mechanisms of caspase activation
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11 July 2018
Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination
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PubMed Central
reference URL
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11 July 2018
The CD95(APO-1/Fas) DISC and beyond
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PubMed Central
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11 July 2018
Insights into the regulatory mechanism for caspase-8 activation
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PubMed Central
reference URL
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11 July 2018
A unified model for apical caspase activation
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PubMed Central
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11 July 2018
Mechanism of XIAP-mediated inhibition of caspase-9
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11 July 2018
NALPs: a novel protein family involved in inflammation
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11 July 2018
Apoptosomes: engines for caspase activation
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PubMed Central
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11 July 2018
The Bcl2 family: regulators of the cellular life-or-death switch
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11 July 2018
IAP proteins: blocking the road to death's door
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PubMed Central
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11 July 2018
Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition
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PubMed Central
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11 July 2018
Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark
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11 July 2018
Mechanisms of caspase activation and inhibition during apoptosis
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PubMed Central
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11 July 2018
Structural basis for the activation of human procaspase-7
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11 July 2018
Dimer formation drives the activation of the cell death protease caspase 9
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides
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PubMed Central
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11 July 2018
A structural view of mitochondria-mediated apoptosis
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PubMed Central
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11 July 2018
Structural basis for the inhibition of caspase-3 by XIAP
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PubMed Central
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11 July 2018
Structural Basis of Caspase Inhibition by XIAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
Structural basis of caspase-7 inhibition by XIAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Structural basis of IAP recognition by Smac/DIABLO
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
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11 July 2018
NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
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PubMed Central
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11 July 2018
The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity
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PubMed Central
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11 July 2018
Mammalian caspases: structure, activation, substrates, and functions during apoptosis
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PubMed Central
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11 July 2018
Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
HAC-1, a Drosophila homolog of APAF-1 and CED-4 functions in developmental and radiation-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
Caspase-9 and APAF-1 form an active holoenzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Biochemical pathways of caspase activation during apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
An emerging blueprint for apoptosis in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Caspase activation: the induced-proximity model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
11 July 2018
The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Caspase-9 can be activated without proteolytic processing
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
IAP family proteins--suppressors of apoptosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Caspases: enemies within
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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11 July 2018
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
1 reference
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PubMed Central
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11 July 2018
Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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24 September 2018
Worms, life, and death (Nobel lecture).
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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24 September 2018
Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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24 September 2018
The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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24 September 2018
Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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24 September 2018
Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
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24 September 2018
Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
24 September 2018
Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2279816
retrieved
24 September 2018
A conserved tetrapeptide motif: potentiating apoptosis through IAP-binding
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15273300
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
An old meaning of the word apoptosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15273300
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1110/PS.04789804
1 reference
stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
PMCID
2279816
1 reference
stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
PubMed ID
15273300
1 reference
stated in
Europe PubMed Central
PMCID
2279816
retrieved
10 August 2017
ResearchGate publication ID
8437007
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