(Q24657908)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding (English)

1 reference

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24 January 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

3

Andrew Ward

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

10

Ina L Urbatsch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

author name string

Stephen G Aller

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Jodie Yu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Srinivas Chittaboina

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Rupeng Zhuo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Patina M Harrell

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Yenphuong T Trinh

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Qinghai Zhang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Geoffrey Chang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

language of work or name

English

0 references

publication date

1 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

volume

323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

page(s)

1718-1722

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

issue

5922

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

Flexibility in the ABC transporter MsbA: Alternating access with a twist

24 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Crystal structure of a catalytic intermediate of the maltose transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

X-ray structure of EmrE supports dual topology model

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Structure of an ABC transporter in complex with its binding protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

An inward-facing conformation of a putative metal-chelate-type ABC transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Crystal structure of bacterial multidrug efflux transporter AcrB

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Structure of a bacterial multidrug ABC transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Targeting multidrug resistance in cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Biochemistry of multidrug resistance mediated by the multidrug transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

ABC multidrug transporters: structure, function and role in chemoresistance.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Structural basis of energy transduction in the transport cycle of MsbA.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Molecular mechanisms of drug resistance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

beta-Amyloid efflux mediated by p-glycoprotein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Extraction of Hoechst 33342 from the cytoplasmic leaflet of the plasma membrane by P-glycoprotein.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Quantification and characterization of P-glycoprotein-substrate interactions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Three-dimensional structures of the mammalian multidrug resistance P-glycoprotein demonstrate major conformational changes in the transmembrane domains upon nucleotide binding

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Three-dimensional structure by cryo-electron microscopy of YvcC, an homodimeric ATP-binding cassette transporter from Bacillus subtilis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Nucleotide-induced structural changes in P-glycoprotein observed by electron microscopy.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Structural and functional fingerprint of the mitochondrial ATP-binding cassette transporter Mdl1 from Saccharomyces cerevisiae

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Involvement of the "occluded nucleotide conformation" of P-glycoprotein in the catalytic pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Simultaneous binding of two different drugs in the binding pocket of the human multidrug resistance P-glycoprotein

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

Large scale purification of detergent-soluble P-glycoprotein from Pichia pastoris cells and characterization of nucleotide binding properties of wild-type, Walker A, and Walker B mutant proteins.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2720052

The functional purification of P-glycoprotein is dependent on maintenance of a lipid-protein interface

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19325113

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of Residues in the Drug-binding Site of Human P-glycoprotein Using a Thiol-reactive Substrate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19325113

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1168750

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

ADS bibcode

2009Sci...323.1718A

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19325113%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

2 references