(Q24676381)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

title

Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Nils Welsh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Natalia Makeeva

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Michael Welsh

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

language of work or name

English

0 references

publication date

1 November 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

page(s)

695-704

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

Isolated mouse pancreatic islets in culture: Effects of serum and different culture media on the insulin production of the islets

16 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Co-operation of simian virus 40 T antigen and insulin receptor substrate-1 in protection from apoptosis induced by interleukin-3 withdrawal

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Interleukin-1 beta-induced ceramide and diacylglycerol generation may lead to activation of the c-Jun NH2-terminal kinase and the transcription factor ATF2 in the insulin-producing cell line RINm5F.

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Tumor necrosis factor alpha-induced pancreatic beta-cell insulin resistance is mediated by nitric oxide and prevented by 15-deoxy-Delta12,14-prostaglandin J2 and aminoguanidine. A role for peroxisome proliferator-activated receptor gamma activation

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Phosphorylation of the PTEN tail regulates protein stability and function

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Dual role of the tyrosine kinase GTK and the adaptor protein SHB in beta-cell growth: enhanced beta-cell replication after 60% pancreatectomy and increased sensitivity to streptozotocin

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Islet mass and function in diabetes and transplantation

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Glucose-induced insulin receptor tyrosine phosphorylation in insulin-secreting beta-cells

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Efficient Gene Transfer to Dispersed Human Pancreatic Islet Cells In Vitro Using Adenovirus-Polylysine/DNA Complexes or Polycationic Liposomes

1 reference

https://api.crossref.org/works/10.1007%2FBF03402033

7 January 2021

Identifiers

DOI

10.1007/BF03402033

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12520086%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PubMed publication ID

12520086

1 reference