(Q24815275)

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Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities.

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4 January 2020

Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities (English)

1 reference

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4 January 2020

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4 January 2020

8

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4 January 2020

author name string

Maddalena Corgnali

2

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4 January 2020

Loïc Perrouault

3

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4 January 2020

Victoria Roig

4

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4 January 2020

Ulysse Asseline

5

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4 January 2020

Mads D Sørensen

6

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4 January 2020

B Ravindra Babu

7

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4 January 2020

Carine Giovannangeli

9

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4 January 2020

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publication date

27 July 2005

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4 January 2020

Nucleic Acids Research

1 reference

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4 January 2020

33

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4 January 2020

13

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4 January 2020

4223-4234

1 reference

Europe PubMed Central

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4 January 2020

Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides

1 reference

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1 reference

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28 September 2017

Exploring cellular activity of locked nucleic acid-modified triplex-forming oligonucleotides and defining its molecular basis

1 reference

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LNA-antisense rivals siRNA for gene silencing

1 reference

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Triplex-forming oligonucleotides - sequence-specific DNA ligands as tools for gene inhibition and for modulation of DNA-associated functions

1 reference

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28 September 2017

Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates

1 reference

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28 September 2017

DNA binding and antigene activity of a daunomycin-conjugated triplex-forming oligonucleotide targeting the P2 promoter of the human c-myc gene

1 reference

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28 September 2017

Targeted gene modification using triplex-forming oligonucleotides

1 reference

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28 September 2017

Use of locked nucleic acid oligonucleotides to add functionality to plasmid DNA

1 reference

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28 September 2017

Triplex formation with 2'-O,4'-C-ethylene-bridged nucleic acids (ENA) having C3'-endo conformation at physiological pH.

1 reference

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28 September 2017

Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme

1 reference

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28 September 2017

In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides

1 reference

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28 September 2017

A directional nucleation-zipping mechanism for triple helix formation

1 reference

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28 September 2017

Design of antisense oligonucleotides stabilized by locked nucleic acids

1 reference

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28 September 2017

Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I.

1 reference

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28 September 2017

Triplex-forming molecules: from concepts to applications

1 reference

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28 September 2017

Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181241

28 September 2017

2'-O,4'-C-Methylene bridged nucleic acid (2',4'-BNA): synthesis and triplex-forming properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181241

28 September 2017

Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181241

28 September 2017

2'-O,4'-C-methylene bridged nucleic acid modification promotes pyrimidine motif triplex DNA formation at physiological pH: thermodynamic and kinetic studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181241

28 September 2017

Triple helix formation with purine-rich phosphorothioate-containing oligonucleotides covalently linked to an acridine derivative

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181241

28 September 2017

Specific inhibition of in vitro transcription elongation by triplex-forming oligonucleotide-intercalator conjugates targeted to HIV proviral DNA.

1 reference

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28 September 2017

Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1181241

28 September 2017

A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence

1 reference

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Synthesis and physicochemical properties of oligonucleotides built with eitherα-L orβ-L nucleotides units and covalently linked to an acridine derivative

1 reference

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28 September 2017

Triple-helix formation by oligonucleotides containing the three bases thymine, cytosine, and guanine

1 reference

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28 September 2017

A computational and experimental study of the bending induced at a double-triple helix junction

1 reference

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1 reference

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28 September 2017

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1 reference

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A novel procedure for quantitative polymerase chain reaction by coamplification of competitive templates

1 reference

https://pubmed.ncbi.nlm.nih.gov/16049028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of cytosine protonation to the stability of parallel DNA triple helices

1 reference

https://pubmed.ncbi.nlm.nih.gov/16049028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted gene knockout mediated by triple helix forming oligonucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/16049028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-helix formation at different positions on nucleosomal DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/16049028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKI726

1 reference

Europe PubMed Central

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4 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16049028%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

Europe PubMed Central

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4 January 2020

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