(Q25256746)

6 July 2017

title

Mg2+ dependency of HIV-1 reverse transcription, inhibition by nucleoside analogues and resistance (English)

1 reference

6 July 2017

Valérie Goldschmidt

1

1 reference

6 July 2017

Joël Didierjean

2

1 reference

6 July 2017

Bernard Ehresmann

3

1 reference

6 July 2017

Chantal Ehresmann

4

1 reference

6 July 2017

Catherine Isel

5

1 reference

6 July 2017

Roland Marquet

6

1 reference

6 July 2017

language of work or name

English

0 references

publication date

3 January 2006

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6 July 2017

published in

Nucleic Acids Research

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6 July 2017

volume

34

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6 July 2017

issue

1

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6 July 2017

page(s)

42-52

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Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors

6 July 2017

cites work

1 reference

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Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase

7 April 2017

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Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

7 April 2017

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

7 April 2017

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In vitro evidence for a long range pseudoknot in the 5'-untranslated and matrix coding regions of HIV-1 genomic RNA

7 April 2017

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A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase

7 April 2017

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Functional characterization of RNA-dependent DNA polymerase and RNase H activities of a recombinant HIV reverse transcriptase

7 April 2017

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HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region

7 April 2017

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Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis

7 April 2017

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Inhibition of human immunodeficiency virus type 1 reverse transcriptase, RNase H, and integrase activities by hydroxytropolones.

7 April 2017

1 reference

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Intracellular substrates for the primer-unblocking reaction by human immunodeficiency virus type 1 reverse transcriptase: detection and quantitation in extracts from quiescent- and activated-lymphocyte subpopulations

28 September 2017

1 reference

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Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision

28 September 2017

1 reference

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Inhibition of HIV-1 reverse transcription: basic principles of drug action and resistance

28 September 2017

1 reference

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The blood brain barrier in HIV infection

28 September 2017

1 reference

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First snapshots of the HIV-1 RNA structure in infected cells and in virions.

28 September 2017

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Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs).

28 September 2017

1 reference

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Nucleoside and nucleotide analogue reverse transcriptase inhibitors: a clinical review of antiretroviral resistance.

28 September 2017

1 reference

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Mutations in the ribonuclease H active site of HIV-RT reveal a role for this site in stabilizing enzyme-primer-template binding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Unique progressive cleavage mechanism of HIV reverse transcriptase RNase H

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Natural endogenous reverse transcription of HIV-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Interaction of retroviral reverse transcriptase with template-primer duplexes during replication.

28 September 2017

1 reference

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Biochemical analysis of catalytically crucial aspartate mutants of human immunodeficiency virus type 1 reverse transcriptase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Broad spectrum antiretroviral activity of 2',3'-dideoxynucleosides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Human immunodeficiency virus 1 reverse transcriptase. Template binding, processivity, strand displacement synthesis, and template switching

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Dimerization of human immunodeficiency virus (type 1) RNA: stimulation by cations and possible mechanism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Human immunodeficiency virus type 1 gag-pol frameshifting is dependent on downstream mRNA secondary structure: demonstration by expression in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activities

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Effect of RNA secondary structure on RNA cleavage catalyzed by HIV-1 reverse transcriptase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Effect of RNA secondary structure on the kinetics of DNA synthesis catalyzed by HIV-1 reverse transcriptase

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Characterization of the RNA dependent DNA polymerase of a new human T lymphotropic retrovirus (lymphadenopathy associated virus)

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Functional purification and enzymic characterization of the RNA-dependent DNA polymerase of human immunodeficiency virus

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Mechanistic insights into the suppression of drug resistance by human immunodeficiency virus type 1 reverse transcriptase using alpha-boranophosphate nucleoside analogs

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Catecholamine-induced regulation in vitro and ex vivo of intralymphocyte ionized magnesium

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

RNA secondary structure and sequence conservation in C1 region of human immunodeficiency virus type 1 env gene

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Hypermagnesemia does not increase brain intracellular magnesium in newborn swine.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Mechanism-based suppression of dideoxynucleotide resistance by K65R human immunodeficiency virus reverse transcriptase using an alpha-boranophosphate nucleoside analogue.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Purification and characterization of human immunodeficiency virus type 1 reverse transcriptase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Functional sites in the 5' region of human immunodeficiency virus type 1 RNA form defined structural domains

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Divalent cation modulation of the ribonuclease functions of human immunodeficiency virus reverse transcriptase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

Human immunodeficiency virus reverse transcriptase-associated RNase H activity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1325016

RNA secondary structure switching during DNA synthesis catalyzed by HIV-1 reverse transcriptase

28 November 2018

1 reference

12 December 2020

Effects of unpaired nucleotides within HIV-1 genomic secondary structures on pausing and strand transfer

1 reference

12 December 2020

pH effects on measurements of ionized calcium and ionized magnesium in blood

1 reference

12 December 2020

Characterization of the AIDS-associated retrovirus reverse transcriptase and optimal conditions for its detection in virions

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKJ411

1 reference

6 July 2017

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6 July 2017

1 reference