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Production of lentiviral vectors
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title
Production of lentiviral vectors
(English)
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author name string
Otto-Wilhelm Merten
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1
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Matthias Hebben
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2
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Chiara Bovolenta
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3
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language of work or name
English
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publication date
2016
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published in
Molecular Therapy. Methods & Clinical Development
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Crossref
volume
3
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page(s)
16017
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cites work
Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia
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A third-generation lentivirus vector with a conditional packaging system
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Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial.
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Lentiviral vectors displaying modified measles virus gp overcome pre-existing immunity in in vivo-like transduction of human T and B cells.
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Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins
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28 September 2017
Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells
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Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
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The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
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Efficient construction of producer cell lines for a SIN lentiviral vector for SCID-X1 gene therapy by concatemeric array transfection
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The F12-Vif derivative Chim3 inhibits HIV-1 replication in CD4+ T lymphocytes and CD34+-derived macrophages by blocking HIV-1 DNA integration
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28 September 2017
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28 September 2017
Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification
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28 September 2017
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28 September 2017
Purification of retroviral vectors for clinical application: biological implications and technological challenges
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28 September 2017
Gene transfer system derived from the caprine arthritis-encephalitis lentivirus
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28 September 2017
A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors.
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Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer
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Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors
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28 September 2017
The use of recombinase mediated cassette exchange in retroviral vector producer cell lines: predictability and efficiency by transgene exchange
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28 September 2017
Downstream processing of oncoretroviral and lentiviral gene therapy vectors
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28 September 2017
Purification and characterization of retrovirus vector particles by rate zonal ultracentrifugation
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28 September 2017
A replication competent lentivirus (RCL) assay for equine infectious anaemia virus (EIAV)-based lentiviral vectors
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28 September 2017
Optimisation of a multipartite human immunodeficiency virus based vector system; control of virus infectivity and large-scale production
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Mobilization and mechanism of transcription of integrated self-inactivating lentiviral vectors
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28 September 2017
Upscaling of lentiviral vector production by tangential flow filtration
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28 September 2017
Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector.
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28 September 2017
Lentiviral vectors: optimization of packaging, transduction and gene expression
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28 September 2017
Certification assays for HIV-1-based vectors: frequent passage of gag sequences without evidence of replication-competent viruses
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28 September 2017
Optimized lentiviral vector production and purification procedure prevents immune response after transduction of mouse brain
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28 September 2017
Comparison of transfection conditions for a lentivirus vector produced in large volumes
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
A new-generation stable inducible packaging cell line for lentiviral vectors
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28 September 2017
Generation of a flexible cell line with regulatable, high-level expression of HIV Gag/Pol particles capable of packaging HIV-derived vectors
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28 September 2017
Identification of a novel posttranscriptional regulatory element by using a rev- and RRE-mutated human immunodeficiency virus type 1 DNA proviral clone as a molecular trap
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28 September 2017
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28 September 2017
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28 September 2017
Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors
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28 September 2017
Gene transfer systems derived from Visna virus: analysis of virus production and infectivity
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28 September 2017
A stable system for the high-titer production of multiply attenuated lentiviral vectors
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
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28 September 2017
Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Production and concentration of pseudotyped HIV-1-based gene transfer vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Stable gene transfer to the nervous system using a non-primate lentiviral vector
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Requirements for efficient production and transduction of human immunodeficiency virus type 1-based vectors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Large-scale processing of recombinant retroviruses for gene therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
A packaging cell line for lentivirus vectors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
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28 September 2017
Development of a self-inactivating lentivirus vector.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Identification of a human immunodeficiency virus type 2 (HIV-2) encapsidation determinant and transduction of nondividing human cells by HIV-2-based lentivirus vectors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
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28 September 2017
Inducible human immunodeficiency virus type 1 packaging cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Construction of stable packaging cell lines for clinical lentiviral vector production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 September 2017
Liver-directed lentiviral gene therapy in a dog model of hemophilia B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
31 May 2018
The HIV-1 Rev response element: an RNA scaffold that directs the cooperative assembly of a homo-oligomeric ribonucleoprotein complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
31 May 2018
Rev-independent expression of synthetic gag-pol genes of human immunodeficiency virus type 1 and simian immunodeficiency virus: implications for the safety of lentiviral vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
31 May 2018
Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Chim3 confers survival advantage to CD4+ T cells upon HIV-1 infection by preventing HIV-1 DNA integration and HIV-1-induced G2 cell-cycle delay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Advantages of COS-1 monkey kidney epithelial cells as packaging host for small-volume production of high-quality recombinant lentiviruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
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28 November 2018
Overview of the HIV-1 Lentiviral Vector System.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Transduction of human hematopoietic stem cells by lentiviral vectors pseudotyped with the RD114-TR chimeric envelope glycoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Production and purification of lentiviral vectors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Development of a sensitive assay for detection of replication-competent recombinant lentivirus in large-scale HIV-based vector preparations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Continuous high-titer HIV-1 vector production.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Efficient gene transfer into the CNS by lentiviral vectors purified by anion exchange chromatography
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830361
retrieved
28 November 2018
Lentivirus vector purification using anion exchange HPLC leads to improved gene transfer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27110581
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Small- to large-scale production of lentivirus vectors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27110581
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transfection of HEK293-EBNA1 Cells in Suspension with Linear PEI for Production of Recombinant Proteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27110581
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RD-MolPack technology for the constitutive production of self-inactivating lentiviral vectors pseudotyped with the nontoxic RD114-TR envelope
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27110581
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/MTM.2016.17
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2330904
OpenCitations bibliographic resource ID
2330904
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2330904
PMC publication ID
4830361
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2330904
PubMed publication ID
27110581
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2330904
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