(Q34397099)

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Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial.

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

phase I clinical trial

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vector-borne disease

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phase II clinical trial

0 references

Parkinson's disease

1 reference

based on heuristic

inferred from title

13

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

19

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

22

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Philippe Le Corvoisier

23

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Roger A. Barker

34

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

36

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Philippe Hantraye

35

object named as

Philippe Hantraye

1 reference

Europe PubMed Central

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4 March 2020

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Stéphane Palfi

1

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4 March 2020

Jean Marc Gurruchaga

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

G Scott Ralph

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Helene Lepetit

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Sonia Lavisse

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Philip C Buttery

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Colin Watts

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

James Miskin

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Michelle Kelleher

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Sarah Deeley

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Hirokazu Iwamuro

11

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Jean Pascal Lefaucheur

12

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Gilles Fenelon

14

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Cherry Lucas

15

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Pierre Brugières

16

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Inanna Gabriel

17

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Kou Abhay

18

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Naoki Tani

20

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Aurelie Kas

21

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Patrice Dolphin

24

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

David P Breen

25

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Sarah Mason

26

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Natalie Valle Guzman

27

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Nicholas D Mazarakis

28

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Pippa A Radcliffe

29

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Europe PubMed Central

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4 March 2020

Richard Harrop

30

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Europe PubMed Central

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4 March 2020

Susan M Kingsman

31

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4 March 2020

Stuart Naylor

33

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Europe PubMed Central

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4 March 2020

Pierre Cesaro

37

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Kyriacos A Mitrophanous

38

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Olivier Rascol

32

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Europe PubMed Central

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4 March 2020

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publication date

10 January 2014

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Europe PubMed Central

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4 March 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

383

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

9923

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1138-1146

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24412048%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Epidemiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Etiology and pathogenesis of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancing aromatic L-amino acid decarboxylase activity: implications for L-DOPA treatment in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Tyrosine hydroxylase and regulation of dopamine synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Serum renin levels and postnephrectomy blood pressure

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

l-Dopa-induced dyskinesia-clinical presentation, genetics, and treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Parkinson disease and impulse control disorders: a review of clinical features, pathophysiology and management

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Stable gene transfer to the nervous system using a non-primate lentiviral vector

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Lentivirus-mediated gene transfer to the central nervous system: therapeutic and research applications

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Lentiviral gene transfer to the nonhuman primate brain

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene therapy for PIDs: progress, pitfalls and prospects

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Dopamine gene therapy for Parkinson's disease in a nonhuman primate without associated dyskinesia.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Core assessment program for surgical interventional therapies in Parkinson's disease (CAPSIT-PD).

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Utility of an objective dyskinesia rating scale for Parkinson's disease: inter- and intrarater reliability assessment.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Parkinson subtypes progress differently in clinical course and imaging pattern

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term replacement of a mutated nonfunctional CNS gene: reversal of hypothalamic diabetes insipidus using an EIAV-based lentiviral vector expressing arginine vasopressin

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Transplantation of embryonic dopamine neurons for severe Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Acute administration of levodopa-benserazide and tolcapone, a COMT inhibitor, Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2813%2961939-X

7 January 2021

based on heuristic

inferred from DOI database lookup

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