(Q38353123)

2 September 2017

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title

Performance-enhancing drugs: design and production of redirected chimeric antigen receptor (CAR) T cells (English)

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2 September 2017

1

B L Levine

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2 September 2017

13 February 2015

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2 September 2017

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2 September 2017

22

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2 September 2017

2

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2 September 2017

79-84

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https://scigraph.springernature.com/pub.10.1038/cgt.2015.5

2 September 2017

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CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients

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T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

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Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia.

21 January 2018

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Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy

21 January 2018

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Chimeric antigen receptor therapy for chronic lymphocytic leukemia: what are the challenges?

21 January 2018

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B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

21 January 2018

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Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells

21 January 2018

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A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19

21 January 2018

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Apheresis techniques and cellular immunomodulation

21 January 2018

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Moderate and severe adverse events associated with apheresis donations: incidences and risk factors

21 January 2018

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Manufacturing of highly functional and specific T cells for adoptive immunotherapy against virus from granulocyte colony-stimulating factor-mobilized donors

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21 January 2018

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Anticoagulation techniques in apheresis: from heparin to citrate and beyond

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Principles of adoptive T cell cancer therapy

21 January 2018

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Expansion and characterization of human melanoma tumor-infiltrating lymphocytes (TILs)

21 January 2018

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GMP production and testing of Xcellerated T Cells for the treatment of patients with CLL.

21 January 2018

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Clinical-scale selection and viral transduction of human naïve and central memory CD8+ T cells for adoptive cell therapy of cancer patients.

21 January 2018

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Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

21 January 2018

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Lentiviral vectors: basic to translational

21 January 2018

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State-of-the-art gene-based therapies: the road ahead

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Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells

21 January 2018

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Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

21 January 2018

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21 January 2018

Bioreactors get personal

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Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.

21 January 2018

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A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2015.5

Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2015.5

Phase 1/2 trial of autologous tumor mixed with an allogeneic GVAX vaccine in advanced-stage non-small-cell lung cancer

21 January 2018

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21 January 2018

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Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity

21 January 2018

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Antigen-independent and antigen-dependent methods to numerically expand CD19-specific CD8+ T cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1038%2FCGT.2015.5

Regimen-specific effects of RNA-modified chimeric antigen receptor T cells in mice with advanced leukemia

21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product

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12 December 2020

T lymphocyte engineering ex vivo for cancer and infectious disease

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12 December 2020

Viral vectors: a look back and ahead on gene transfer technology

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12 December 2020

Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience

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12 December 2020

Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones

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12 December 2020

Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells.

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12 December 2020

Supplemental guidance on testing for replication-competent retrovirus in retroviral vector-based gene therapy products and during follow-up of patients in clinical trials using retroviral vectors

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12 December 2020

Stem cell mobilization.

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12 December 2020

Clinical application of Sleeping Beauty and artificial antigen presenting cells to genetically modify T cells from peripheral and umbilical cord blood

1 reference

12 December 2020

Impaired induction of the CD28-responsive complex in granulocyte colony-stimulating factor mobilized CD4 T cells

1 reference

12 December 2020

Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1038/CGT.2015.5

1 reference

PubMed ID

25675873

Dimensions Publication ID

2 September 2017

0 references

1 reference

PubMed ID

25675873