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P2X receptors as targets for the treatment of status epilepticus
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PubMed
title
P2X receptors as targets for the treatment of status epilepticus
(English)
1 reference
stated in
PubMed
main subject
status epilepticus
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based on heuristic
inferred from title
author
David Henshall
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
Miguel Diaz-Hernandez
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
María Teresa Miras Portugal
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
Tobias Engel
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
author name string
M. Teresa Miras-Portugal
series ordinal
3
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
26 November 2013
1 reference
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PubMed
published in
Frontiers in Cellular Neuroscience
2 references
stated in
Crossref
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
volume
7
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
page(s)
237
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
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31 May 2018
Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice.
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31 May 2018
P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia.
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Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice
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P2X7 receptor modulation on microglial cells and reduction of brain infarct caused by middle cerebral artery occlusion in rat.
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31 May 2018
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices
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A novel neuronal P2x ATP receptor ion channel with widespread distribution in the brain
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Involvement of P2X4 receptors in hippocampal microglial activation after status epilepticus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Extracellular ATP differentially affects epileptiform activity via purinergic P2X7 and adenosine A1 receptors in naive and chronic epileptic rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
The neuroprotective effect of a specific P2X₇ receptor antagonist derives from its ability to inhibit assembly of the NLRP3 inflammasome in glial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
The roles of P2X7 receptor in regional-specific microglial responses in the rat brain following status epilepticus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Ischemic preconditioning requires opening of pannexin-1/P2X(7) channels not only during preconditioning but again after index ischemia at full reperfusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
P2X7 receptor differentially modulates astroglial apoptosis and clasmatodendrosis in the rat brain following status epilepticus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Molecular mechanisms of drug resistance in status epilepticus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Blockade of P2X receptor prevents astroglial death in the dentate gyrus following pilocarpine-induced status epilepticus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Alteration of purinergic P2X4 and P2X7 receptor expression in rats with temporal-lobe epilepsy induced by pilocarpine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Possible involvement of P2X7 receptor activation in microglial neuroprotection against focal cerebral ischemia in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Cellular localization of P2X7 receptor mRNA in the rat brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
P2 receptor antagonist trinitrophenyl-adenosine-triphosphate protects hippocampus from oxygen and glucose deprivation cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
P2X7 receptor immunoreactive profile confined to resting and activated microglia in the epileptic brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
P2X receptor activation elicits transporter-mediated noradrenaline release from rat hippocampal slices
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
P2X2 and P2X4 receptor expression is regulated by a GABA(A) receptor-mediated mechanism in the gerbil hippocampus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Role of P2X7 receptors in ischemic and excitotoxic brain injury in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
P2X7 receptor-mediated release of excitatory amino acids from astrocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Role for P2X receptors in long-term potentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Activation of presynaptic P2X7-like receptors depresses mossy fiber-CA3 synaptic transmission through p38 mitogen-activated protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
ADP and AMP induce interleukin-1beta release from microglial cells through activation of ATP-primed P2X7 receptor channels.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Distribution of the P2X2 receptor subunit of the ATP-gated ion channels in the rat central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Increased amount of extracellular ATP in stimulated hippocampal slices of seizure prone mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3840793
retrieved
28 November 2018
Treatment options for status epilepticus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24324404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: Evidence from purine biosensors and P2 receptor agonists and antagonists
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24324404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of P2X5 receptors in the mouse CNS
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24324404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mouse microglial cells express a plasma membrane pore gated by extracellular ATP
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24324404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reanalysis of P2X7 receptor expression in rodent brain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24324404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The treatment of status epilepticus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24324404
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FNCEL.2013.00237
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913016
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
Fatcat ID
release_yrjvqg4tefgylf6d4yclnwoyii
0 references
OpenCitations bibliographic resource ID
913016
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913016
PMC publication ID
3840793
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913016
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
PubMed publication ID
24324404
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913016
stated in
Europe PubMed Central
PMC publication ID
3840793
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24324404%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
ResearchGate publication ID
259268607
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