(Q26824012)

Rainer Spanagel

series ordinal

2

1 reference

John H. Krystal

series ordinal

3

1 reference

language of work or name

1 reference

October 2013

1 reference

1 reference

229

1 reference

issue

3

1 reference

page(s)

539-54

1 reference

Promise of mGluR2/3 activators in psychiatry

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Neuropharmacology of alcohol addiction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Glutamatergic substrates of drug addiction and alcoholism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Intracellular signaling pathways that regulate behavioral responses to ethanol

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Increased glutamatergic neurotransmission and oxidative stress after alcohol withdrawal

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

The role of glutamatergic neurotransmission in the pathophysiology of alcoholism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Differential effects of chronic ethanol consumption and withdrawal on homer/glutamate receptor expression in subregions of the accumbens and amygdala of P rats

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Ethanol-induced alterations of amino acids measured by in vivo microdialysis in rats: a meta-analysis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

GluN2B in corticostriatal circuits governs choice learning and choice shifting.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Enhanced AMPA receptor activity increases operant alcohol self-administration and cue-induced reinstatement

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Meta-analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Neuroimmunophilin GPI-1046 reduces ethanol consumption in part through activation of GLT1 in alcohol-preferring rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effect of repeated treatment with topiramate on voluntary alcohol intake and beta-endorphin plasma level in Warsaw alcohol high-preferring rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Attenuation of reinstatement of methamphetamine-, sucrose-, and food-seeking behavior in rats by fenobam, a metabotropic glutamate receptor 5 negative allosteric modulator

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Calcium-permeable AMPA receptors in the VTA and nucleus accumbens after cocaine exposure: when, how, and why?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Drug-evoked plasticity: do addictive drugs reopen a critical period of postnatal synaptic development?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Chronic alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortex

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Attenuation of methamphetamine seeking by the mGluR2/3 agonist LY379268 in rats with histories of restricted and escalated self-administration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Ceftriaxone upregulates the glutamate transporter in medial prefrontal cortex and blocks reinstatement of methamphetamine seeking in a condition place preference paradigm

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Glutamate, GABA, and other cortical metabolite concentrations during early abstinence from alcohol and their associations with neurocognitive changes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Ethanol up-regulates nucleus accumbens neuronal activity dependent pentraxin (Narp): implications for alcohol-induced behavioral plasticity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Behavioral and neurotransmitter specific roles for the ventral tegmental area in reinforcer-seeking and intake

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

New pharmacological treatment strategies for relapse prevention

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Chronic intermittent ethanol and withdrawal differentially modulate basolateral amygdala AMPA-type glutamate receptor function and trafficking

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Circadian and acamprosate modulation of elevated ethanol drinking in mPer2 clock gene mutant mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanol

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Severity of drinking as a predictor of efficacy of the combination of ondansetron and topiramate in rat models of ethanol consumption and relapse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Ceftriaxone, a beta-lactam antibiotic, reduces ethanol consumption in alcohol-preferring rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Treatment of alcohol dependence with low-dose topiramate: an open-label controlled study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Characterization of the interactive effects of glycine and D-cycloserine in men: further evidence for enhanced NMDA receptor function associated with human alcohol dependence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

PER2 variation is associated with diurnal preference in a Korean young population

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

The metabotropic glutamate receptor subtype 5 mediates sensitivity to the sedative properties of ethanol

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Glycine transporter-1 blockade leads to persistently reduced relapse-like alcohol drinking in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Metabotropic glutamate receptor subtype 5 antagonism in learning and memory

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Glutamate-based antidepressants: 20 years on.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effect of topiramate treatment on ethanol consumption in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

The mGlu5 receptor antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) supports intravenous self-administration and induces conditioned place preference in the rat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effects of D-cycloserine on extinction and reconditioning of ethanol-seeking behavior in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Role of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

The expression of NMDA receptor subunit mRNA in human chronic alcoholics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Mechanisms of neurodegeneration and regeneration in alcoholism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Comparing topiramate with naltrexone in the treatment of alcohol dependence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effects of topiramate and other anti-glutamatergic drugs on the acute intoxicating actions of ethanol in mice: modulation by genetic strain and stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Acute effects of acamprosate and MPEP on ethanol Drinking-in-the-Dark in male C57BL/6J mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Voluntary ethanol intake enhances excitatory synaptic strength in the ventral tegmental area.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions: blockade by the mGluR5 antagonist MPEP

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Role of major NMDA or AMPA receptor subunits in MK-801 potentiation of ethanol intoxication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effects of the mGluR2/3 agonist LY379268 and the mGluR5 antagonist MPEP on handling-induced convulsions during ethanol withdrawal in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effects of topiramate on urge to drink and the subjective effects of alcohol: a preliminary laboratory study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Topiramate for treating alcohol dependence: a randomized controlled trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Chronic ethanol and withdrawal differentially modulate pre- and postsynaptic function at glutamatergic synapses in rat basolateral amygdala

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Drug addiction as a pathology of staged neuroplasticity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Alcohol inhibits NR2B-containing NMDA receptors in the ventral bed nucleus of the stria terminalis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Combined antagonism of glutamate mGlu5 and adenosine A2A receptors interact to regulate alcohol-seeking in rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Zonisamide decreases ethanol intake in rats and mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Chronic intermittent ethanol treatment selectively alters N-methyl-D-aspartate receptor subunit surface expression in cultured cortical neurons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male wistar rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Assessing appetitive and consummatory phases of ethanol self-administration in C57BL/6J mice under operant conditions: regulation by mGlu5 receptor antagonism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Glutamate and schizophrenia: beyond the dopamine hypothesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-administration in alcohol-preferring (P) rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811052

Effect of oral acamprosate on abstinence in patients with alcohol dependence in a double-blind, placebo-controlled trial: the role of patient motivation

28 September 2017

1 reference

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The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice.

28 September 2017

1 reference

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Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking

28 September 2017

1 reference

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The metabotropic glutamate 5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]-pyridine reduces ethanol self-administration in multiple strains of alcohol-preferring rats and regulates olfactory glutamatergic systems

28 September 2017

1 reference

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Neurocircuitry in alcoholism: a substrate of disruption and repair

28 September 2017

1 reference

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Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism

28 September 2017

1 reference

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Signaling cascades regulating NMDA receptor sensitivity to ethanol

28 September 2017

1 reference

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Ethanol and brain plasticity: receptors and molecular networks of the postsynaptic density as targets of ethanol

28 September 2017

1 reference

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N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability

28 September 2017

1 reference

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Alcohol potently inhibits the kainate receptor-dependent excitatory drive of hippocampal interneurons.

28 September 2017

1 reference

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Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue

28 September 2017

1 reference

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Ethanol and NMDA receptor signaling

28 September 2017

1 reference

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Regulation of NMDA receptors by ethanol

28 September 2017

1 reference

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Pharmacological treatment of alcohol dependence: a review of the evidence

28 September 2017

1 reference

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Disulfiram treatment of alcoholism. A Veterans Administration cooperative study

28 September 2017

1 reference

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NMDA agonists and antagonists alter the hypnotic response to ethanol in LS and SS mice

28 September 2017

1 reference

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Ethanol withdrawal seizures and the NMDA receptor complex

28 September 2017

1 reference

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Accumbens Homer2-mediated signaling: a factor contributing to mouse strain differences in alcohol drinking?

28 September 2017

1 reference

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Metabotropic glutamate 5 receptors regulate sensitivity to ethanol in mice

31 May 2018

1 reference

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31 May 2018

1 reference

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Chronic ethanol ingestion modulates proanxiety factors expressed in rat central amygdala

31 May 2018

1 reference

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Effects of topiramate in the treatment of alcohol dependence.

31 May 2018

1 reference

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Chronic ethanol upregulates NMDA and AMPA, but not kainate receptor subunit proteins in rat primary cortical cultures.

31 May 2018

1 reference

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D-cycloserine blocks the effects of ethanol and HA-966 in rats tested in the elevated plus-maze

31 May 2018

1 reference

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Discriminative stimulus effects of ethanol: lack of antagonism with N-methyl-D-aspartate and D-cycloserine.

31 May 2018

1 reference

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Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

31 May 2018

1 reference

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Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum.

31 May 2018

1 reference

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An N-methylaspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine?

31 May 2018

1 reference

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Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones

31 May 2018

1 reference

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Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

31 May 2018

1 reference

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Actions of D-cycloserine at the N-methyl-D-aspartate-associated glycine receptor site in vivo

31 May 2018

1 reference

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Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino-3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes

31 May 2018

1 reference

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Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

31 May 2018

1 reference

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Implications for glycine receptors and astrocytes in ethanol-induced elevation of dopamine levels in the nucleus accumbens

31 May 2018

1 reference

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Cannabinoid-induced increase in relapse-like drinking is prevented by the blockade of the glycine-binding site of N-methyl-D-aspartate receptors

21 January 2018

1 reference

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mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior

21 January 2018

1 reference

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Ionotropic glutamate receptor antagonists modulate cue-induced reinstatement of ethanol-seeking behavior

21 January 2018

1 reference

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Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG.

21 January 2018

1 reference

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Involvement of AMPA/kainate, NMDA, and mGlu5 receptors in the nucleus accumbens core in cue-induced reinstatement of cocaine seeking in rats.

21 January 2018

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Blockade of the acquisition of ethanol-induced conditioned place preference by N-methyl-D-aspartate receptor antagonists.

21 January 2018

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Acute effects of memantine in combination with alcohol in moderate drinkers.

21 January 2018

1 reference

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The role of NMDA receptor binding sites in ethanol place conditioning

21 January 2018

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Functional roles of NMDA receptor NR2A and NR2B subunits in the acute intoxicating effects of ethanol in mice

21 January 2018

1 reference

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Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice

21 January 2018

1 reference

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Alcohol effects during acamprosate treatment: a dose-response study in humans

21 January 2018

1 reference

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A microdialysis study of extracellular levels of acamprosate and naltrexone in the rat brain following acute and repeated administration

21 January 2018

1 reference

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Topiramate attenuates withdrawal signs after chronic intermittent ethanol in rats

21 January 2018

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Chronic ethanol induces synaptic but not extrasynaptic targeting of NMDA receptors.

21 January 2018

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Alcohol-induced neurodegeneration, suppression of transforming growth factor-beta, and cognitive impairment in rats: prevention by group II metabotropic glutamate receptor activation

21 January 2018

1 reference

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Neurobehavioral effects of alcohol in AMPA receptor subunit (GluR1) deficient mice

21 January 2018

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Effects of acamprosate on excitatory amino acids during multiple ethanol withdrawal periods.

21 January 2018

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A pilot double-blind treatment trial of memantine for alcohol dependence.

21 January 2018

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Persisting changes in basolateral amygdala mRNAs after chronic ethanol consumption

21 January 2018

1 reference

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Topiramate (Topamax) reduces conditioned abstinence behaviours and handling-induced convulsions (HIC) after chronic administration of alcohol in Swiss-Webster mice.

21 January 2018

1 reference

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Effects of N-acetylcysteine on alcohol abstinence and alcohol-induced adverse effects in rats

21 January 2018

1 reference

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Using topiramate or naltrexone for the treatment of alcohol-dependent patients

21 January 2018

1 reference

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Chronic ethanol ingestion facilitates N-methyl-D-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons

21 January 2018

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Glutamate receptors in the cingulate cortex, hippocampus, and cerebellar vermis of alcoholics.

21 January 2018

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Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial

21 January 2018

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Topiramate does not affect the acquisition or expression of ethanol conditioned place preference in DBA/2J or C57BL/6J mice.

21 January 2018

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Topiramate moderately reduces the motivation to consume alcohol and has a marked antidepressant effect in rats.

21 January 2018

1 reference

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Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists

21 January 2018

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Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats

21 January 2018

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Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats.

21 January 2018

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Use of naltrexone for alcohol use disorders in the Veterans' Health Administration: a national study

21 January 2018

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Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial

21 January 2018

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Oral topiramate for treatment of alcohol dependence: a randomised controlled trial

21 January 2018

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AMPA receptor potentiation can prevent ethanol-induced intoxication.

21 January 2018

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Effect of D-cycloserine on rapid tolerance to ethanol.

21 January 2018

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D-cycloserine enhances rapid tolerance to ethanol motor incoordination.

21 January 2018

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The NMDA/glycine receptor antagonist, L-701,324, produces discriminative stimuli similar to those of ethanol.

21 January 2018

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The role of group I mGlu receptors in the expression of ethanol-induced conditioned place preference and ethanol withdrawal seizures in rats.

21 January 2018

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Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients.

21 January 2018

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The effects of alcoholism on the human basolateral amygdala

21 January 2018

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21 January 2018

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Potentiation of the ambulation-increasing effect induced by combined administration of MK-801 with ethanol in mice.

21 January 2018

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Ethanol inhibition of kainate receptor-mediated excitatory neurotransmission in the rat basolateral nucleus of the amygdala

21 January 2018

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The glycine reuptake inhibitor Org24598 and acamprosate reduce ethanol intake in the rat; tolerance development to acamprosate but not to Org24598.

21 January 2018

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Timing-dependent reduction in ethanol sedation and drinking preference by NMDA receptor co-agonist d-serine.

21 January 2018

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Ethanol inhibits NMDA-activated ion current in hippocampal neurons

21 January 2018

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Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking

21 January 2018

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Bivalent effects of MK-801 on ethanol-induced sensitization do not parallel its effects on ethanol-induced tolerance

21 January 2018

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Glycine receptors regulate dopamine release in the rat nucleus accumbens

21 January 2018

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Ethanol Inhibits α-Amino-3-hydyroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Function in Central Nervous System Neurons by Stabilizing Desensitization

21 January 2018

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Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach.

21 January 2018

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Topiramate reduces ethanol consumption by C57BL/6 mice.

21 January 2018

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The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism

21 January 2018

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Novelty-seeking behaviors and the escalation of alcohol drinking after abstinence in mice are controlled by metabotropic glutamate receptor 5 on neurons expressing dopamine d1 receptors

21 January 2018

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Altered NMDA Glutamate Receptor Antagonist Response in Individuals With a Family Vulnerability to Alcoholism

21 January 2018

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Acute and chronic ethanol alter glutamatergic transmission in rat central amygdala: an in vitro and in vivo analysis.

21 January 2018

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Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse.

21 January 2018

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The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats.

21 January 2018

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Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior

21 January 2018

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Acamprosate and alcohol: III. Effects on alcohol discrimination in the rat.

21 January 2018

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Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantine

21 January 2018

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Absence of significant interactive effects of high-dose D-cycloserine and ethanol in healthy human subjects: preliminary insights into ethanol actions at the glycine B site of NMDA glutamate receptors

21 January 2018

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Interaction of ethanol with excitatory amino acid receptor antagonists in mice.

21 January 2018

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The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect

21 January 2018

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D-cycloserine facilitates extinction of conditioned alcohol-seeking behaviour in rats

21 January 2018

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NMDA receptors in frontal cortex and hippocampus of alcohol consumers.

21 January 2018

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Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories.

21 January 2018

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Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala.

21 January 2018

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The thorny side of addiction: adaptive plasticity and dendritic spines.

21 January 2018

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Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam.

28 November 2018

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Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects

28 November 2018

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Two cases of alcohol craving curbed by topiramate.

28 November 2018

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Expression of behavioral sensitization to ethanol by DBA/2J mice: the role of NMDA and non-NMDA glutamate receptors

28 November 2018

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Ionotropic glutamate receptor subunit expression in the rat hippocampus: lack of an effect of a long-term ethanol exposure paradigm

28 November 2018

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Disruption of operant oral self-administration of ethanol, sucrose, and saccharin by the AMPA/kainate antagonist, NBQX, but not the AMPA antagonist, GYKI 52466.

28 November 2018

1 reference

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Ethanol inhibition of synaptically evoked kainate responses in rat hippocampal CA3 pyramidal neurons.

28 November 2018

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NMDA-dependent modulation of CA1 local circuit inhibition.

28 November 2018

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Discriminative stimulus effects of ethanol: effect of training dose on the substitution of N-methyl-D-aspartate antagonists.

28 November 2018

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Modulation of NMDA receptors by glycine ? introduction to some basic aspects and recent developments

28 November 2018

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12 December 2020

Association between a polymorphism in the promoter of a glutamate receptor subunit gene (GRIN2A) and alcoholism

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Biphasic effect of ethanol on extracellular accumulation of glutamate in the hippocampus and the nucleus accumbens

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Acute effects of ethanol on kainate receptors in cultured hippocampal neurons

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Up-regulation of cortical AMPA receptor binding in the fawn-hooded rat following ethanol withdrawal

1 reference

12 December 2020

Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons

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12 December 2020

Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers

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12 December 2020

MK-801 potentiates ethanol's effects on locomotor activity in mice

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12 December 2020

A pilot study of Topiramate (Topamax) in the treatment of tonic-clonic seizures of alcohol withdrawal syndromes

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12 December 2020

Ethanol and N -methyl- D -aspartate receptor complex interactions: a detailed drug discrimination study in the rat

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12 December 2020

Naltrexone in the treatment of alcohol dependence

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12 December 2020

Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes

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12 December 2020

10.1007/S00213-013-3226-2

Identifiers

DOI

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Dimensions Publication ID

1018976673

0 references

1 reference

1 reference

PubMed publication ID

23995381

1 reference