(Q34104364)

31 July 2017

title

The metabotropic glutamate receptor subtype 5 mediates sensitivity to the sedative properties of ethanol (English)

1 reference

31 July 2017

1 reference

4

Thomas E Johnson

1 reference

31 July 2017

Chris Downing

1

1 reference

31 July 2017

Michael J Marks

series ordinal

2

1 reference

31 July 2017

Colin Larson

series ordinal

3

1 reference

31 July 2017

language of work or name

1 reference

1 September 2010

1 reference

Pharmacogenetics and Genomics

31 July 2017

published in

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31 July 2017

volume

20

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31 July 2017

issue

9

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31 July 2017

page(s)

553-564

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Metabotropic glutamate receptor ligands as potential therapeutics for addiction

31 July 2017

cites work

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Metabotropic glutamate 5 receptors regulate sensitivity to ethanol in mice

5 July 2018

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Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions

5 July 2018

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Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats.

5 July 2018

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Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice

5 July 2018

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Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype

5 July 2018

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mGlu5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in rats

5 July 2018

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Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties.

5 July 2018

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The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice.

5 July 2018

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Norepinephrine transporter: a candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice.

5 July 2018

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The search for genes contributing to the low level of response to alcohol: patterns of findings across studies

5 July 2018

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Protein measurement with the Folin phenol reagent

5 July 2018

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Gene structure of the human metabotropic glutamate receptor 5 and functional analysis of its multiple promoters in neuroblastoma and astroglioma cells

5 July 2018

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Interallelic complementation at the mouse Mitf locus.

5 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

5 July 2018

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The genetic architecture of quantitative traits

5 July 2018

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Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory

5 July 2018

1 reference

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No effect of albinism on sedative-hypnotic sensitivity to ethanol and anesthetics

5 July 2018

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mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors

5 July 2018

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Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Assessing the risk for alcoholism among sons of alcoholics.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Genetic interactions between naturally occurring alleles at quantitative trait loci and mutant alleles at candidate loci affecting bristle number in Drosophila melanogaster

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Low level of response to alcohol as a predictor of future alcoholism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.

5 July 2018

1 reference

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A biometrical genetic analysis of ethanol response in selectively bred long-sleep and short-sleep mice.

5 July 2018

1 reference

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Differential effects of central nervous system depressants in long-sleep and short-sleep mice.

5 July 2018

1 reference

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LS X SS recombinant inbred strains of mice: initial characterization

5 July 2018

1 reference

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A recombinant inbred strain analysis of sleep-time responses to several sedative-hypnotics.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Classical genetic analyses of responses to sedative-hypnotic drugs in crosses derived from long-sleep and short-sleep mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Ketamine, but not propofol, anaesthesia is regulated by metabotropic glutamate 5 receptors.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Complementing complexity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Mapping quantitative trait loci mediating sensitivity to etomidate

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

The search for genes related to a low-level response to alcohol determined by alcohol challenges

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Inhibition of mGluR5 blocks hippocampal LTP in vivo and spatial learning in rats

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Reciprocal congenics defining individual quantitative trait Loci for sedative/hypnotic sensitivity to ethanol

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

A genome-wide search for genes that relate to a low level of response to alcohol

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Identification of a genetic region in mice that specifies sensitivity to propofol.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

A multivariate analysis of repeated measures: linkage of the albinism gene (Tyr) to a QTL influencing ethanol-induced anesthesia in laboratory mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Stimulant and depressant properties of sedative-hypnotics in mice selectively bred for differential sensitivity to ethanol.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Distinctions among sedative, disinhibitory, and ataxic properties of ethanol in inbred and selectively bred mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Intronic MicroRNA: Discovery and Biological Implications

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933419

Towards the cloning of genes underlying murine QTLs

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20657349

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/FPC.0B013E32833D8C20

1 reference

31 July 2017

1 reference

31 July 2017

1 reference