(Q33788860)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice (English)

1 reference

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9 January 2020

1

1 reference

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9 January 2020

author name string

Michael F Miles

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Amanda C Sharko

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Rebekah A Stevenson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Jennie R Hillmann

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Veronique Lepoutre

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Joyce Besheer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Jason P Schroeder

8

1 reference

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9 January 2020

publication date

15 November 2005

1 reference

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9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

429-438

1 reference

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https://scigraph.springernature.com/pub.10.1007/s00213-005-0217-y

9 January 2020

exact match

0 references

cites work

The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

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The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats

4 July 2018

1 reference

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Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.

4 July 2018

1 reference

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Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking

4 July 2018

1 reference

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GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice.

4 July 2018

1 reference

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In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

4 July 2018

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The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice

4 July 2018

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NMDA receptor pathways as drug targets

4 July 2018

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The origin and neuronal function of in vivo nonsynaptic glutamate.

4 July 2018

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Aspartate and glutamate transport in acutely and chronically ethanol exposed neonatal rat primary astrocyte cultures

4 July 2018

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Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites

4 July 2018

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Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

4 July 2018

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Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders

4 July 2018

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Role of polyamines and NMDA receptors in ethanol dependence and withdrawal.

4 July 2018

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Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

4 July 2018

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Glutamate-mediated transmission, alcohol, and alcoholism

4 July 2018

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mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination

4 July 2018

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A review of the effects of prenatal or early postnatal ethanol exposure on brain ligand-gated ion channels

4 July 2018

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Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon

4 July 2018

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Group I metabotropic glutamate receptors: implications for brain diseases

4 July 2018

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Acute effects of ethanol on GABAA and glycine receptor function

4 July 2018

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Ionotropic glutamate receptors as sites of action for ethanol in the brain

4 July 2018

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The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions.

4 July 2018

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Role of taste and calories in the selection of ethanol by C57BL/6NHsd and Hsd:ICR mice

4 July 2018

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Acute ethanol alters calcium signals elicited by glutamate receptor agonists and K+ depolarization in cultured cerebellar Purkinje neurons

4 July 2018

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Metabotropic glutamate receptor agonists alter neuronal excitability and Ca2+ levels via the phospholipase C transduction pathway in cultured Purkinje neurons

4 July 2018

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Toward a definition of a valid model of alcoholism: multiple animal models for multiple diseases

4 July 2018

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Intake of ethanol, sodium chloride, sucrose, citric acid, and quinine hydrochloride solutions by mice: a genetic analysis

4 July 2018

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Chronic ethanol on mRNA levels of IP3R1, IP3 3-kinase and mGluR1 in mouse Purkinje neurons.

4 July 2018

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Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus

4 July 2018

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Ethanol consumption and taste preferences in C57BL/6ByJ and 129/J mice

4 July 2018

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Specific decreases in ethanol- but not water-reinforced responding produced by the 5-HT3 antagonist ICS 205-930.

4 July 2018

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Ethanol, sedative hypnotics, and glutamate receptor function in brain and cultured cells

4 July 2018

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The metabotropic glutamate receptors: structure and functions

4 July 2018

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Ethanol action on excitatory amino acid activated ion channels

4 July 2018

1 reference

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Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats.

4 July 2018

1 reference

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Drugs of abuse: behavioural principles, methods and terms

4 July 2018

1 reference

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NMDA receptor complex antagonists have ethanol-like discriminative stimulus effects

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Ethanol drinking by rhesus monkeys with concurrent access to water

4 July 2018

1 reference

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Chronic ethanol treatment and withdrawal alter ACPD-evoked calcium signals in developing Purkinje neurons

4 July 2018

1 reference

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The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Role of gamma-aminobutyric acid (GABA) and metabotropic glutamate receptors in nicotine reinforcement: potential pharmacotherapies for smoking cessation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Effects of NMDA glutamate receptor antagonist drugs on the volitional consumption of ethanol by a genetic drinking rat.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Chronic ethanol-induced subtype- and subregion-specific decrease in the mRNA expression of metabotropic glutamate receptors in rat hippocampus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Ionotropic glutamate receptor antagonists modulate cue-induced reinstatement of ethanol-seeking behavior

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Neuropeptide-Y Y5 receptors modulate the onset and maintenance of operant ethanol self-administration

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Group I metabotropic glutamate receptors in the monkey striatum: subsynaptic association with glutamatergic and dopaminergic afferents.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

The discriminative stimulus properties of self-administered ethanol are mediated by GABA(A) and NMDA receptors in rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Modulation of NMDA receptors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Alcohol self-administration: further examination of the role of dopamine receptors in the nucleus accumbens.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Dopamine receptors in the medial prefrontal cortex influence ethanol and sucrose-reinforced responding.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Effects of ventral tegmental microinjections of the GABAA agonist muscimol on self-administration of ethanol and sucrose.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Ventral tegmental microinjections of quinpirole decrease ethanol and sucrose-reinforced responding.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Effect of dopamine agonists and antagonists on ethanol-reinforced behavior: the involvement of the nucleus accumbens.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Effects of intraaccumbens injections of dopamine agonists and antagonists on sucrose and sucrose-ethanol reinforced responding.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Effects of ethanol on stimulated inositol phospholipid hydrolysis in rat brain.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854492

Second messenger pathways involved in up-regulation of an L-type calcium channel

30 October 2018

1 reference

12 December 2020

Relation of ethanol self-administration to feeding and drinking in a nonrestricted access situation in rats initiated to self-administer ethanol using the sucrose-fading technique

1 reference

12 December 2020

Drinking of high concentrations of ethanol versus palatable fluids in alcohol-preferring (P) rats: valid animal model of alcoholism

1 reference

12 December 2020

Pharmacological analysis of the mixed discriminative stimulus effects of ethanol

1 reference

12 December 2020

Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

1 reference

12 December 2020

10.1007/S00213-005-0217-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16292590%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

16292590

1 reference