(Q26830671)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

systematic review

1 reference

PubMed publication ID

24777052

meta-analysis

1 reference

PubMed publication ID

1 reference

8 February 2021

Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

phosphatidylinositol 3-kinase

16 March 2020

main subject

1 reference

28 September 2019

1 reference

26 August 2020

AKT serine/threonine kinase 1

1 reference

Serine/threonine-protein kinase TOR

1 September 2020

1 reference

28 January 2021

1 reference

8 February 2021

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

Verónica Corrales-Sánchez

16 March 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Eitan Amir

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

4

Arnoud J Templeton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

8

Bostjan Seruga

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

9

Atanasio Pandiella

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Francisco Vera-Badillo

2

object named as

Francisco Vera-Badillo

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

6

Laura Diez-Gonzalez

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

3

Mustafa Al-Mubarak

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

author name string

María D Cuenca-Lopez

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

language of work or name

1 reference

28 April 2014

9 references

3 April 2019

2 August 2019

28 September 2019

18 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

26 August 2020

1 September 2020

28 January 2021

8 February 2021

10 references

3 April 2019

2 August 2019

28 September 2019

18 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

26 August 2020

1 September 2020

28 January 2021

8 February 2021

9

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

issue

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

page(s)

e95219

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

16 March 2020

copyright license

8 references

3 April 2019

2 August 2019

28 September 2019

18 December 2019

26 August 2020

1 September 2020

28 January 2021

on focus list of Wikimedia project

8 February 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

1 reference

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The PI3K pathway as drug target in human cancer

7 April 2017

1 reference

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The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Protein tyrosine phosphatases in the human genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

The evolving landscape of protein kinases in breast cancer: clinical implications.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

PTEN protein loss by immunostaining: analytic validation and prognostic indicator for a high risk surgical cohort of prostate cancer patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

The role of mTOR and phospho-p70S6K in pathogenesis and progression of gastric carcinomas: an immunohistochemical study on tissue microarray

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

PIK3CA mutation associates with improved outcome in breast cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Drug discovery approaches targeting the PI3K/Akt pathway in cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

The cancer biomarker problem

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial

28 September 2017

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

PIK3CA mutations in endometrial carcinomas in Chinese women: phosphatidylinositol 3'-kinase pathway alterations might be associated with favorable prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

PIK3CA mutations in breast cancer are associated with poor outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

AKT activation predicts outcome in breast cancer patients treated with tamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

Clinicopathological correlations of mTOR and pAkt expression in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

Overexpression of phosphorylated mammalian target of rapamycin predicts lymph node metastasis and prognosis of chinese patients with gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

Clinical significance of tumor suppressor PTEN in colorectal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095219

Biomarker analyses in CLEOPATRA: a phase III, placebo-controlled study of pertuzumab in human epidermal growth factor receptor 2-positive, first-line metastatic breast cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4002433

Different prognostic roles of mutations in the helical and kinase domains of the PIK3CA gene in breast carcinomas

28 November 2018

1 reference

12 December 2020

PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients

1 reference

12 December 2020

Phosphorylation of Akt (Ser473) predicts poor clinical outcome in oropharyngeal squamous cell cancer

1 reference

12 December 2020

Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer

1 reference

12 December 2020

Oncogenic targets, magnitude of benefit, and market pricing of antineoplastic drugs

1 reference

12 December 2020

Loss of PTEN expression followed by Akt phosphorylation is a poor prognostic factor for patients with endometrial cancer

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0095219

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

ADS bibcode

2014PLoSO...995219O

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

PubMed publication ID

24777052

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777052%20AND%20SRC:MED&resulttype=core&format=json