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Posttranscriptional RNA Modifications: playing metabolic games in a cell's chemical Legoland
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title
Posttranscriptional RNA Modifications: playing metabolic games in a cell's chemical Legoland
(English)
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author
Mark Helm
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Mark Helm
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1
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author name string
Juan D. Alfonzo
series ordinal
2
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language of work or name
English
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publication date
20 February 2014
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published in
Chemistry and Biology
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PubMed
volume
21
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PubMed
issue
2
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PubMed
page(s)
174-85
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PubMed
cites work
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Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification
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Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA
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PubMed Central
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Purification and characterization of the human elongator complex
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Kissing G domains of MnmE monitored by X-ray crystallography and pulse electron paramagnetic resonance spectroscopy
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7 April 2017
Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4
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PubMed Central
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7 April 2017
Solution conformations of unmodified and A(37)N(6)-dimethylallyl modified anticodon stem-loops of Escherichia coli tRNA(Phe)
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7 April 2017
A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.
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PubMed Central
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7 April 2017
Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins
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Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases
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The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA.
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Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA.
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PubMed Central
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7 April 2017
Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis
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PubMed Central
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An early step in wobble uridine tRNA modification requires the Elongator complex
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PubMed Central
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Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases
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A primordial tRNA modification required for the evolution of life?
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7 April 2017
Competition between a sterol biosynthetic enzyme and tRNA modification in addition to changes in the protein synthesis machinery causes altered nonsense suppression
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PubMed Central
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MODOMICS: a database of RNA modification pathways--2013 update
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PubMed Central
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7 April 2017
Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation
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7 April 2017
Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift
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PubMed Central
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7 April 2017
A quantitative systems approach reveals dynamic control of tRNA modifications during cellular stress
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7 April 2017
Discovery and biological characterization of geranylated RNA in bacteria
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Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase
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Influence of threonine metabolism on S-adenosylmethionine and histone methylation
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28 September 2017
4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate
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PubMed Central
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28 September 2017
Biosynthesis and function of posttranscriptional modifications of transfer RNAs
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28 September 2017
Enzymology of tRNA modification in the bacterial MnmEG pathway.
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28 September 2017
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine
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PubMed Central
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28 September 2017
A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification
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PubMed Central
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28 September 2017
Elongator function in tRNA wobble uridine modification is conserved between yeast and plants.
1 reference
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PubMed Central
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28 September 2017
Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea
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PubMed Central
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28 September 2017
A gripping tale of ribosomal frameshifting: extragenic suppressors of frameshift mutations spotlight P-site realignment
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PubMed Central
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28 September 2017
Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors
1 reference
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PubMed Central
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28 September 2017
tRNA's modifications bring order to gene expression
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PubMed Central
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28 September 2017
Role of a tRNA base modification and its precursors in frameshifting in eukaryotes
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PubMed Central
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28 September 2017
Elongator complex: how many roles does it play?
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PubMed Central
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28 September 2017
Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA.
1 reference
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PubMed Central
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28 September 2017
The structure of the TrmE GTP-binding protein and its implications for tRNA modification
1 reference
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PubMed Central
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28 September 2017
tRNA-guanine transglycosylase from E. coli: a ping-pong kinetic mechanism is consistent with nucleophilic catalysis
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PubMed Central
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28 September 2017
Transfer RNA modifications that alter +1 frameshifting in general fail to affect -1 frameshifting
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PubMed Central
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28 September 2017
Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944000
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28 September 2017
Summary: the modified nucleosides of RNA.
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PubMed Central
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28 September 2017
The role of posttranscriptional modification in stabilization of transfer RNA from hyperthermophiles
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PubMed Central
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28 September 2017
Structure of yeast phenylalanine tRNA at 3 Å resolution
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944000
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28 September 2017
Three-Dimensional Tertiary Structure of Yeast Phenylalanine Transfer RNA
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PubMed Central
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28 September 2017
Affinity electrophoresis for monitoring terminal phosphorylation and the presence of queuosine in RNA. Application of polyacrylamide containing a covalently bound boronic acid.
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PubMed Central
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28 September 2017
Thiolation of transfer RNA in Escherichia coli varies with growth rate
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PubMed Central
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28 September 2017
The tRNA-modifying function of MnmE is controlled by post-hydrolysis steps of its GTPase cycle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944000
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31 May 2018
Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases
1 reference
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31 May 2018
Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus
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PubMed Central
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31 May 2018
Interaction of tRNAs and of phosphorothioate-substituted nucleic acids with an organomercurial. Probing the chemical environment of thiolated residues by affinity electrophoresis
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31 May 2018
Method for comparative analysis of ribonucleic acids using isotope labeling and mass spectrometry.
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28 November 2018
Mechanism and Stem-Cell Activity of 5-Carboxycytosine Decarboxylation Determined by Isotope Tracing
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28 November 2018
Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome
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28 November 2018
Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions.
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PubMed Central
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28 November 2018
Novel taurine-containing uridine derivatives and mitochondrial human diseases
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PubMed
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12 December 2020
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STUDIES ON POLYNUCLEOTIDES. XLI. PURIFICATION OF PHENYLALANINE-SPECIFIC TRANSFER RIBONUCLEIC ACID FROM YEAST BY COUNTERCURRENT DISTRIBUTION
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24315934
retrieved
12 December 2020
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Identifiers
DOI
10.1016/J.CHEMBIOL.2013.10.015
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856398
Fatcat ID
release_cvoixwd76rg7rjxfudankjqi24
1 reference
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/cvoixwd76rg7rjxfudankjqi24
retrieved
24 November 2022
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mapped directly with Wikidata item
OpenCitations bibliographic resource ID
1856398
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856398
PMCID
3944000
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856398
PubMed ID
24315934
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1856398
ResearchGate publication ID
259246187
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