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Structure, function, and modulation of GABA(A) receptors
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title
Structure, function, and modulation of GABA(A) receptors
(English)
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PubMed
author name string
E. Sigel
series ordinal
1
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M. E. Steinmann
series ordinal
2
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Crossref
language of work or name
English
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stated in
PubMed
publication date
23 November 2012
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published in
Journal of Biological Chemistry
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PubMed
volume
287
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PubMed
issue
48
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PubMed
page(s)
40224-31
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PubMed
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Neurosteroids: endogenous regulators of the GABA(A) receptor
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Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital
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GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus
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Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors
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Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator.
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Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors
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Structural link between γ-aminobutyric acid type A (GABAA) receptor agonist binding site and inner β-sheet governs channel activation and allosteric drug modulation
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The major central endocannabinoid directly acts at GABA A receptors
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Characteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes
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The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs
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A Closer Look at the High Affinity Benzodiazepine Binding Site on GABAA Receptors
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Mutations in GABAA receptor subunits associated with genetic epilepsies
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RNA editing and its impact on GABAA receptor function
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Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABA receptors
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GABA, a natural immunomodulator of T lymphocytes
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Covalent modification of GABAA receptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs
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Consequences of the evolution of the GABA(A) receptor gene family
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28 September 2017
Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety
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28 September 2017
Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A receptors.
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Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans
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On the Benzodiazepine Binding Pocket in GABAA Receptors
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EXP-1 is an excitatory GABA-gated cation channel
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Modulation of GABAA receptor activity by phosphorylation and receptor trafficking: implications for the efficacy of synaptic inhibition
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Comparative modeling of GABA(A) receptors: limits, insights, future developments.
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28 September 2017
Coupling of agonist binding to channel gating in the GABA(A) receptor
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The inhibitory glycine receptor-simple views of a complicated channel
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Subunit composition, distribution and function of GABA(A) receptor subtypes
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Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.
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Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.
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28 September 2017
Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes.
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28 September 2017
GABAA receptor channels
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28 September 2017
gamma-Aminobutyric acid receptor channels in adrenal chromaffin cells: a patch-clamp study
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28 September 2017
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28 September 2017
Docking of 1,4-benzodiazepines in the alpha1/gamma2 GABA(A) receptor modulator site
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The benzodiazepine binding site of GABAA receptors
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Unravelling the role of GABAA receptor subtypes in distinct neurons and behaviour
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
retrieved
28 November 2018
Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
A GABA(A) receptor of defined subunit composition and positioning: concatenation of five subunits.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
retrieved
28 November 2018
Analysis of the set of GABA(A) receptor genes in the human genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
retrieved
28 November 2018
Individual properties of the two functional agonist sites in GABA(A) receptors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
retrieved
28 November 2018
Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
retrieved
28 November 2018
Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
Cysteine mutants as chemical sensors for ligand-receptor interactions
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
Molecular and neuronal substrate for the selective attenuation of anxiety.
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
Subunit composition and quantitative importance of hetero-oligomeric receptors: GABAA receptors containing alpha6 subunits.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
Amino acids lining the channel of the gamma-aminobutyric acid type A receptor identified by cysteine substitution
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3504738
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28 November 2018
A gamma-aminobutyric acid/benzodiazepine receptor complex of bovine cerebral cortex
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PubMed Central
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28 November 2018
Molecular heterogeneity of benzodiazepine receptors
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/23038269
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Purification by affinity chromatography of the glycine receptor of rat spinal cord
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23038269
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Influence of GABA-gated bicarbonate conductance on potential, current and intracellular chloride in crayfish muscle fibres
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23038269
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Decreased hepatocyte membrane potential differences and GABAA-beta3 expression in human hepatocellular carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23038269
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1074/JBC.R112.386664
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1478589
OpenCitations bibliographic resource ID
1478589
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1478589
PMC publication ID
3504738
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1478589
PubMed publication ID
23038269
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1478589
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