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Toward a Molecular Classification of Colorectal Cancer: The Role of MGMT
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scholarly article
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stated in
PubMed
title
Toward a Molecular Classification of Colorectal Cancer: The Role of MGMT
(English)
1 reference
stated in
PubMed
main subject
colorectal cancer
1 reference
based on heuristic
inferred from title
colorectal carcinoma
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based on heuristic
inferred from title
author name string
Parham Minoo
series ordinal
1
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
18 October 2013
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stated in
PubMed
published in
Frontiers in Oncology
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stated in
Crossref
volume
3
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PubMed
page(s)
266
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PubMed
cites work
O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problems
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CpG island methylator phenotype in colorectal cancer
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21 March 2017
The role of MGMT testing in clinical practice: a report of the association for molecular pathology
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21 March 2017
MGMT gene silencing and benefit from temozolomide in glioblastoma
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21 March 2017
O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer
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PubMed Central
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21 March 2017
Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features
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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
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7 April 2017
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
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7 April 2017
O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer
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PubMed Central
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28 September 2017
Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
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28 September 2017
Comparative assessment of 5 methods (methylation-specific polymerase chain reaction, MethyLight, pyrosequencing, methylation-sensitive high-resolution melting, and immunohistochemistry) to analyze O6-methylguanine-DNA-methyltranferase in a series of
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PubMed Central
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28 September 2017
Why do results conflict regarding the prognostic value of the methylation status in colon cancers? The role of the preservation method
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PubMed Central
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28 September 2017
O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction
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28 September 2017
MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers
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PubMed Central
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28 September 2017
Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
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28 September 2017
Targeting O⁶-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy
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PubMed Central
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28 September 2017
Role of the serrated pathway in colorectal cancer pathogenesis
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PubMed Central
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28 September 2017
MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
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28 September 2017
DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer.
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PubMed Central
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28 September 2017
Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
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28 September 2017
Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma
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PubMed Central
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28 September 2017
Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis.
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PubMed Central
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28 September 2017
Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
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PubMed Central
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28 September 2017
Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer
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28 September 2017
MGMT promoter methylation and field defect in sporadic colorectal cancer.
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PubMed Central
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28 September 2017
Serrated adenoma of the colorectum and the DNA-methylator phenotype
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
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28 September 2017
Low microsatellite instability is associated with poor prognosis in stage C colon cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
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28 September 2017
Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype.
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PubMed Central
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28 September 2017
MGMT: its role in cancer aetiology and cancer therapeutics
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
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28 September 2017
CpG island methylation in aberrant crypt foci of the colorectum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 September 2017
Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
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28 September 2017
Molecular features of colorectal hyperplastic polyps and sessile serrated adenoma/polyps from Korea.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Response to temozolomide in patients with metastatic colorectal cancer with loss of MGMT expression: a new approach in the era of personalized medicine?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Hypermethylation of O6-methylguanine-DNA methyltransferase promoter may predict nonrecurrence after chemotherapy in colorectal cancer cases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Low-level microsatellite instability in most colorectal carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C --> A:T mutations of the TP53 tumor suppressor gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3798865
retrieved
28 November 2018
Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24151575
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24151575
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ki-ras proto-oncogene mutations in sporadic colorectal adenomas: relationship to histologic and clinical characteristics
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24151575
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Sessile serrated adenoma (SSA) vs. traditional serrated adenoma (TSA)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24151575
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Support for hMLH1 and MGMT silencing as a mechanism of tumorigenesis in the hyperplastic-adenoma-carcinoma (serrated) carcinogenic pathway in the colon
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24151575
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24151575
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FONC.2013.00266
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Fatcat ID
release_hzrbs4lvwvbrzksr5ahvo5g2ji
1 reference
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/hzrbs4lvwvbrzksr5ahvo5g2ji
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3798865
1 reference
stated in
PubMed
PubMed publication ID
24151575
1 reference
stated in
PubMed
ResearchGate publication ID
258037392
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