(Q27001182)

title

Involvement of 14-3-3 Proteins in Regulating Tumor Progression of Hepatocellular Carcinoma (English)

0 references

main subject

hepatocellular carcinoma

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Yi-Ju Wu

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Yee-Jee Jan

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Shu-Man Liang

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Jun-Yang Liou

5

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

1 reference

15 June 2015

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

7

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

1022-1036

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 June 2020

copyright license

start time

15 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition

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A novel binding factor of 14-3-3beta functions as a transcriptional repressor and promotes anchorage-independent growth, tumorigenicity, and metastasis

21 March 2017

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Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling

21 March 2017

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Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins

21 March 2017

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Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

21 March 2017

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Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins

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Activation of Raf-1 by 14-3-3 proteins

21 March 2017

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Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins

21 March 2017

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Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma

21 March 2017

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 March 2017

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 March 2017

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BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival

21 March 2017

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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 March 2017

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Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

21 March 2017

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Aberrant upregulation of 14-3-3σ and EZH2 expression serves as an inferior prognostic biomarker for hepatocellular carcinoma

21 March 2017

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The role of epigenetic inactivation of 14-3-3sigma in human cancer

21 March 2017

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A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity

21 March 2017

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BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

21 March 2017

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21 March 2017

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14-3-3σ induces heat shock protein 70 expression in hepatocellular carcinoma

7 April 2017

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14-3-3σ stabilizes a complex of soluble actin and intermediate filament to enable breast tumor invasion

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3ε overexpression contributes to epithelial-mesenchymal transition of hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Expression of partitioning defective 3 (Par-3) for predicting extrahepatic metastasis and survival with hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

αB-crystallin complexes with 14-3-3ζ to induce epithelial-mesenchymal transition and resistance to sorafenib in hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Increased expression of 14-3-3β promotes tumor progression and predicts extrahepatic metastasis and worse survival in hepatocellular carcinoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Aberrant upregulation of 14-3-3ơ expression serves as an inferior prognostic biomarker for gastric cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Post-translational modification of 14-3-3 isoforms and regulation of cellular function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

High expression of stratifin is a universal abnormality during the course of malignant progression of early-stage lung adenocarcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Isoform-specific expression and characterization of 14-3-3 proteins in human glioma tissues discovered by stable isotope labeling with amino acids in cell culture-based proteomic analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3 binding sites in the snail protein are essential for snail-mediated transcriptional repression and epithelial-mesenchymal differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Overexpression of xCT induces up-regulation of 14-3-3beta in Kaposi's sarcoma

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Bortezomib suppresses focal adhesion kinase expression via interrupting nuclear factor-kappa B.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3sigma, the double-edged sword of human cancers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Biomarkers for epithelial-mesenchymal transitions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3 gamma is stimulated by IL-3 and promotes cell proliferation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3sigma Modulates pancreatic cancer cell survival and invasiveness

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Transcriptional regulation of cell polarity in EMT and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Human 14-3-3 gamma protein results in abnormal cell proliferation in the developing eye of Drosophila melanogaster

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Over-expression of 14-3-3sigma in budding colorectal cancer cells modulates cell migration in the presence of tenascin-C.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Overexpression of 14-3-3gamma causes polyploidization in H322 lung cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Structural basis for protein-protein interactions in the 14-3-3 protein family

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Focal adhesion kinase: a potential target in cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3 proteins as potential oncogenes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Small heat shock proteins HSP27 and alphaB-crystallin: cytoprotective and oncogenic functions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Focal adhesion regulation of cell behavior.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

The 14-3-3 cancer connection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Hypomethylation of the 14-3-3σ promoter leads to increased expression in non-small cell lung cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Role of the beta isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4491697

Nonsteroidal anti-inflammatory drugs induced endothelial apoptosis by perturbing peroxisome proliferator-activated receptor-delta transcriptional pathway

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Isoform-specific expression of 14-3-3 proteins in human astrocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Identification of human hepatocellular carcinoma-related biomarkers by two-dimensional difference gel electrophoresis and mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Forced expression of antisense 14-3-3beta RNA suppresses tumor cell growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Aberrant stratifin overexpression is regulated by tumor-associated CpG demethylation in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Hepatocellular carcinoma-associated protein markers investigated by MALDI-TOF MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Identification of differentially expressed genes in papillary thyroid carcinomas with and without rearrangements of the tyrosine kinase receptors RET and/or NTRK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Overexpressed focal adhesion kinase predicts a higher incidence of extrahepatic metastasis and worse survival in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FCANCERS7020822

Overexpression of 14-3-3ε predicts tumour metastasis and poor survival in hepatocellular carcinoma

21 January 2018

1 reference

12 December 2020

Frequent down-regulation of E-cadherin by genetic and epigenetic changes in the malignant progression of hepatocellular carcinomas

1 reference

12 December 2020

Role of Raf in vascular protection from distinct apoptotic stimuli

1 reference

12 December 2020

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase

1 reference

12 December 2020

Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions

1 reference

12 December 2020

Isoform-specific expression of 14-3-3 proteins in human lung cancer tissues

1 reference

12 December 2020

Involvement of 14-3-3γ overexpression in extrahepatic metastasis of hepatocellular carcinoma

1 reference

12 December 2020

Protection of endothelial survival by peroxisome proliferator-activated receptor-delta mediated 14-3-3 upregulation

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs induce colorectal cancer cell apoptosis by suppressing 14-3-3epsilon

1 reference

12 December 2020

Upregulation of focal adhesion kinase by 14-3-3ε via NFκB activation in hepatocellular carcinoma

1 reference

12 December 2020

The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas

1 reference

12 December 2020

Silencing of 14-3-3ζ over-expression in hepatocellular carcinoma inhibits tumor growth and enhances chemosensitivity to cis-diammined dichloridoplatium

1 reference

12 December 2020

Identifiers

DOI

10.3390/CANCERS7020822

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

release_smcnpmkixjbjboqgy5nmb7euqi

13 June 2020

Fatcat ID

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

26083935

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26083935%20AND%20SRC:MED&resulttype=core&format=json