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Bile acids, obesity, and the metabolic syndrome
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
Bile acids, obesity, and the metabolic syndrome
(English)
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main subject
obesity
0 references
metabolic syndrome
1 reference
based on heuristic
inferred from title
author name string
Huijuan Ma
series ordinal
1
1 reference
stated in
Crossref
Mary Elizabeth Patti
series ordinal
2
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
August 2014
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stated in
PubMed
published in
Best Practice and Research: Clinical Gastroenterology
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stated in
PubMed
volume
28
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stated in
PubMed
issue
4
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stated in
PubMed
page(s)
573-83
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stated in
PubMed
cites work
Bile acid metabolism and signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
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21 March 2017
The role of bile after Roux-en-Y gastric bypass in promoting weight loss and improving glycaemic control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
21 March 2017
FXR signaling in the enterohepatic system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
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21 March 2017
Bile acids: regulation of synthesis
1 reference
stated in
PubMed Central
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21 March 2017
THE INTRALUMINAL PHASE OF FAT DIGESTION IN MAN: THE LIPID CONTENT OF THE MICELLAR AND OIL PHASES OF INTESTINAL CONTENT OBTAINED DURING FAT DIGESTION AND ABSORPTION
1 reference
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PubMed Central
reference URL
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21 March 2017
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
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21 March 2017
A G protein-coupled receptor responsive to bile acids
1 reference
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PubMed Central
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21 March 2017
Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice
1 reference
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PubMed Central
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21 March 2017
Identification of membrane-type receptor for bile acids (M-BAR)
1 reference
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PubMed Central
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21 March 2017
Vitamin D receptor as an intestinal bile acid sensor
1 reference
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PubMed Central
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21 March 2017
Bile acids: natural ligands for an orphan nuclear receptor
1 reference
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PubMed Central
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21 March 2017
Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor
1 reference
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PubMed Central
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21 March 2017
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
1 reference
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PubMed Central
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21 March 2017
FXR is a molecular target for the effects of vertical sleeve gastrectomy
1 reference
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PubMed Central
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21 March 2017
Colesevelam HCl improves glycemic control and reduces LDL cholesterol in patients with inadequately controlled type 2 diabetes on sulfonylurea-based therapy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
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21 March 2017
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
1 reference
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PubMed Central
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21 March 2017
Regulation of pyruvate dehydrogenase kinase expression by the farnesoid X receptor
1 reference
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PubMed Central
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21 March 2017
Regulation of bile acid synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
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21 March 2017
The farnesoid X-receptor is an essential regulator of cholesterol homeostasis
1 reference
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PubMed Central
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21 March 2017
Ursodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytes
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PubMed Central
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21 March 2017
Farnesoid X receptor is essential for normal glucose homeostasis
1 reference
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PubMed Central
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21 March 2017
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice
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PubMed Central
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21 March 2017
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
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7 April 2017
Lactobacillus acidophilus NCFM affects vitamin E acetate metabolism and intestinal bile acid signature in monocolonized mice
1 reference
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PubMed Central
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28 September 2017
Bariatric surgery versus intensive medical therapy for diabetes--3-year outcomes
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PubMed Central
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28 September 2017
Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice.
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PubMed Central
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28 September 2017
Fasting serum taurine-conjugated bile acids are elevated in type 2 diabetes and do not change with intensification of insulin
1 reference
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PubMed Central
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28 September 2017
The bile acid TGR5 membrane receptor: from basic research to clinical application
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28 September 2017
Retinoic acid-related orphan receptor α regulates diurnal rhythm and fasting induction of sterol 12α-hydroxylase in bile acid synthesis
1 reference
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PubMed Central
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28 September 2017
GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats
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28 September 2017
Human insulin resistance is associated with increased plasma levels of 12α-hydroxylated bile acids
1 reference
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PubMed Central
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28 September 2017
A role for fibroblast growth factor 19 and bile acids in diabetes remission after Roux-en-Y gastric bypass
1 reference
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28 September 2017
The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders.
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28 September 2017
Roux-en-Y gastric bypass normalizes the blunted postprandial bile acid excursion associated with obesity
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PubMed Central
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28 September 2017
Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids.
1 reference
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PubMed Central
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28 September 2017
Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
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PubMed Central
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28 September 2017
Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats
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28 September 2017
Bile acid binding resin improves metabolic control through the induction of energy expenditure
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28 September 2017
TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
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PubMed Central
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28 September 2017
Conjugated bile acids associate with altered rates of glucose and lipid oxidation after Roux-en-Y gastric bypass
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28 September 2017
Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia
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PubMed Central
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28 September 2017
Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome
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28 September 2017
Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure
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28 September 2017
Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity
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28 September 2017
Plasma bile acids are not associated with energy metabolism in humans
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28 September 2017
Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice
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28 September 2017
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system.
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28 September 2017
The bile acid sensor FXR regulates insulin transcription and secretion
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PubMed Central
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28 September 2017
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats
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28 September 2017
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism
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28 September 2017
Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice
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28 September 2017
Role of bile acids and bile acid receptors in metabolic regulation
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28 September 2017
The role of FXR in disorders of bile acid homeostasis
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28 September 2017
Fifty years of advances in bile acid synthesis and metabolism
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28 September 2017
Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity
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28 September 2017
Targeting bile-acid signalling for metabolic diseases
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28 September 2017
Bile acids and signal transduction: role in glucose homeostasis
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28 September 2017
Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics
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28 September 2017
Bile acid sequestrants and the treatment of type 2 diabetes mellitus
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28 September 2017
Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: a scientific review
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28 September 2017
Endocrine functions of bile acids
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28 September 2017
Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice
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28 September 2017
The Farnesoid X receptor: a molecular link between bile acid and lipid and glucose metabolism
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28 September 2017
Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.
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28 September 2017
The farnesoid X receptor induces very low density lipoprotein receptor gene expression
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28 September 2017
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
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28 September 2017
Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1.
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28 September 2017
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
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28 September 2017
Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass
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31 May 2018
Bile acids and gut peptide secretion after bariatric surgery: a 1-year prospective randomized pilot trial
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31 May 2018
Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults
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31 May 2018
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1.
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31 May 2018
Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation
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31 May 2018
Necdin and E2F4 are modulated by rosiglitazone therapy in diabetic human adipose and muscle tissue
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31 May 2018
Mid to distal small bowel resection with the preservation of the terminal ileum improves glucose homeostasis in diabetic rats by activating the hindgut-dependent mechanism.
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28 November 2018
The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress.
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28 November 2018
Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Are bile acids the new gut hormones? Lessons from weight loss surgery models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: a randomised controlled study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Antiatherosclerotic effect of farnesoid X receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Efficacy and safety of colesevelam in patients with type 2 diabetes mellitus and inadequate glycemic control receiving insulin-based therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Biotransformation of lithocholic acid by rat hepatic microsomes: metabolite analysis by liquid chromatography/mass spectrometry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Colestimide lowers plasma glucose levels and increases plasma glucagon-like PEPTIDE-1 (7-36) levels in patients with type 2 diabetes mellitus complicated by hypercholesterolemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
A phylogenetic survey of biliary lipids in vertebrates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Acute effects of dietary fat composition on postprandial plasma bile acid and cholecystokinin concentrations in healthy premenopausal women
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Ursodeoxycholate mobilizes intracellular Ca2+ and activates phosphorylase a in isolated hepatocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4159616
retrieved
28 November 2018
Cholesterol 7 alpha-hydroxylase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25194176
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cholesterol 7 alpha-hydroxylase of rat liver: an insulin sensitive enzyme
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25194176
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Bile acid kinetics in relation to endogenous tryglyceride metabolism in various types of hyperlipoproteinemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25194176
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25194176
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Bile acid pool changes and regulation of cholate synthesis in experimental diabetes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25194176
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of cholestyramine and chenodeoxycholic acid on the metabolism of endogenous triglyceride in hyperlipoproteinemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25194176
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BPG.2014.07.004
0 references
PMCID
4159616
1 reference
stated in
PubMed
PubMed ID
25194176
1 reference
stated in
PubMed
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