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Bile acids: regulation of synthesis
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
Bile acids: regulation of synthesis
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
main subject
cell biology
0 references
author
John Chiang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
author name string
John Y L Chiang
series ordinal
1
0 references
language of work or name
English
0 references
publication date
3 April 2009
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
published in
Journal of Lipid Research
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
volume
50
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
page(s)
1955-1966
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
issue
10
1 reference
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
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The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
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Regulation of bile acid synthesis
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7 April 2017
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
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7 April 2017
Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP
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7 April 2017
Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase
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7 April 2017
Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha
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7 April 2017
Bifunctional role of Rev-erbalpha in adipocyte differentiation
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Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4
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7 April 2017
Cloning and regulation of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis
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7 April 2017
DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally
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7 April 2017
Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythm
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7 April 2017
Regulation of cholesterol 7 alpha-hydroxylase in the liver. Cloning, sequencing, and regulation of cholesterol 7 alpha-hydroxylase mRNA
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7 April 2017
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
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7 April 2017
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
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7 April 2017
Bile acids: chemistry, physiology, and pathophysiology
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28 September 2017
Nuclear receptors as therapeutic targets in cholestatic liver diseases.
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28 September 2017
Role of bile acids and bile acid receptors in metabolic regulation
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28 September 2017
Mechanism of vitamin D receptor inhibition of cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes
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28 September 2017
Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration
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28 September 2017
The role of FXR in disorders of bile acid homeostasis
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28 September 2017
Endocrine and paracrine role of bile acids
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28 September 2017
Targeting bile-acid signalling for metabolic diseases
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28 September 2017
Bile acids and signal transduction: role in glucose homeostasis
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28 September 2017
TGFbeta1, TNFalpha, and insulin signaling crosstalk in regulation of the rat cholesterol 7alpha-hydroxylase gene expression
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28 September 2017
Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver
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28 September 2017
Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics
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28 September 2017
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis.
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28 September 2017
Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock.
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28 September 2017
Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.
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Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation.
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28 September 2017
Bile acid-mediated thrombospondin-1 induction in hepatocytes leads to transforming growth factor-beta-dependent hepatic stellate cell activation.
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28 September 2017
Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism
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28 September 2017
PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine
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28 September 2017
Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.
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28 September 2017
Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.
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28 September 2017
Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells
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PubMed Central
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28 September 2017
Endocrine functions of bile acids
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PubMed Central
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28 September 2017
Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock
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PubMed Central
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28 September 2017
Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids
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PubMed Central
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28 September 2017
Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis
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PubMed Central
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28 September 2017
Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4.
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28 September 2017
Nuclear receptor regulation of lipid metabolism: potential therapeutics for dyslipidemia, diabetes, and chronic heart and liver diseases.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Role of FXR in regulating bile acid homeostasis and relevance for human diseases
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28 September 2017
Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease?
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28 September 2017
Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho
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28 September 2017
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
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28 September 2017
Molecular basis of intrahepatic cholestasis
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28 September 2017
Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.
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PubMed Central
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28 September 2017
Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Functional role of G9a-induced histone methylation in small heterodimer partner-mediated transcriptional repression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARgamma ligands
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP.
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PubMed Central
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28 September 2017
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Rhythmic expression of DEC1 and DEC2 in peripheral tissues: DEC2 is a potent suppressor for hepatic cytochrome P450s opposing DBP.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Genetic cholestasis, causes and consequences for hepatobiliary transport
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
PGC-1α Activates CYP7A1 and Bile Acid Biosynthesis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha).
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Leptin induces the hepatic high density lipoprotein receptor scavenger receptor B type I (SR-BI) but not cholesterol 7alpha-hydroxylase (Cyp7a1) in leptin-deficient (ob/ob) mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Bile acid regulation of gene expression: roles of nuclear hormone receptors.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 September 2017
Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Mechanisms of cholestasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
FXR, a bile acid receptor and biological sensor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Transcriptional activation of the cholesterol 7alpha-hydroxylase gene (CYP7A) by nuclear hormone receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Identification and characterization of a putative bile acid-responsive element in cholesterol 7 alpha-hydroxylase gene promoter
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Molecular cloning of cDNA for cholesterol 7 alpha-hydroxylase from rat liver microsomes. Nucleotide sequence and expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Rat liver cholesterol 7 alpha-hydroxylase. Pretranslational regulation for circadian rhythm.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 September 2017
Hep G2 cells: a model for studies on regulation of human cholesterol 7alpha-hydroxylase at the molecular level
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 September 2017
Nuclear bile acid receptor FXR protects against intestinal tumorigenesis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
30 May 2018
Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
30 May 2018
Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
30 May 2018
One or more labile proteins regulate the stability of chimeric mRNAs containing the 3'-untranslated region of cholesterol-7alpha -hydroxylase mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
30 May 2018
The 3'-untranslated region of the mouse cholesterol 7alpha-hydroxylase mRNA contains elements responsive to post-transcriptional regulation by bile acids
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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30 May 2018
Regulation of cholesterol 7 alpha-hydroxylase in the liver. Purification of cholesterol 7 alpha-hydroxylase and the immunochemical evidence for the induction of cholesterol 7 alpha-hydroxylase by cholestyramine and circadian rhythm
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
30 May 2018
Regulation of cholesterol and bile acid homoeostasis in bile-obstructed rats
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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30 May 2018
Treatment of preestablished diet-induced fatty liver by oral fatty acid-bile acid conjugates in rodents
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Hepatocyte growth factor signaling pathway inhibits cholesterol 7alpha-hydroxylase and bile acid synthesis in human hepatocytes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Nongenomic actions of bile acids. Synthesis and preliminary characterization of 23- and 6,23-alkyl-substituted bile acid derivatives as selective modulators for the G-protein coupled receptor TGR5.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Conjugated bile acids regulate hepatocyte glycogen synthase activity in vitro and in vivo via Galphai signaling
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Effects of fasting and re-feeding on the expression of Dec1, Per1, and other clock-related genes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Bile acids induce mitochondrial ROS, which promote activation of receptor tyrosine kinases and signaling pathways in rat hepatocytes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Differential regulation of cytosolic and peroxisomal bile acid amidation by PPAR alpha activation favors the formation of unconjugated bile acids
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Bile acids enhance the activity of the insulin receptor and glycogen synthase in primary rodent hepatocytes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
The role of alpha1-fetoprotein transcription factor/LRH-1 in bile acid biosynthesis: a known nuclear receptor activator that can act as a suppressor of bile acid biosynthesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Faecal sterol output is increased by arachidyl amido cholanoic acid (Aramchol) in rats
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Hepatocyte Nuclear Factor 4α Is a Central Regulator of Bile Acid Conjugation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Redundant pathways for negative feedback regulation of bile acid production
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Dissolution of cholesterol gallstones in mice by the oral administration of a fatty acid bile acid conjugate
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
Arachidyl amido cholanoic acid (Aramchol) is a cholesterol solubilizer and prevents the formation of cholesterol gallstones in inbred mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
retrieved
28 November 2018
The peroxisome proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Molecular pathogenesis of cholestasis.
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28 November 2018
Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7 alpha-hydroxylase in rats with biliary fistulas.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Repression of cholesterol 7 alpha-hydroxylase transcription by bile acids is mediated through protein kinase C in primary cultures of rat hepatocytes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739756
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28 November 2018
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/19346330
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Circadian rhythms of sterol 12alpha-hydroxylase, cholesterol 7alpha-hydroxylase and DBP involved in rat cholesterol catabolism
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/19346330
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Peroxisome proliferator-activated receptor alpha (PPARalpha) and agonist inhibit cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19346330
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19346330
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19346330
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of a bile acid response element in the cholesterol 7 alpha-hydroxylase gene CYP7A
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19346330
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cholesterol 7 alpha-hydroxylase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19346330
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
On the mechanism of bile acid inhibition of rat sterol 12α-hydroxylase gene (CYP8B1) transcription: roles of α-fetoprotein transcription factor and hepatocyte nuclear factor 4α
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1194%2FJLR.R900010-JLR200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Platelet adhesion in hypertension: application of a novel assay of platelet adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1194%2FJLR.R900010-JLR200
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1194/JLR.R900010-JLR200
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
631752
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
OpenCitations bibliographic resource ID
631752
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
631752
PMCID
2739756
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
631752
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
PubMed ID
19346330
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
631752
stated in
Europe PubMed Central
PMCID
2739756
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19346330%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 January 2020
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