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TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities
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title
TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities
(English)
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author name string
Rohan Samarakoon
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1
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Jessica M. Overstreet
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2
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Paul J. Higgins
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3
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language of work or name
English
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publication date
January 2013
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published in
Cellular Signalling
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PubMed
volume
25
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PubMed
issue
1
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PubMed
page(s)
264-8
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PubMed
cites work
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Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response
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p53 Phosphorylation at serine 15 is required for transcriptional induction of the plasminogen activator inhibitor-1 (PAI-1) gene by the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine
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The potent lipid mitogen sphingosylphosphocholine activates the DNA binding activity of upstream stimulating factor (USF), a basic helix-loop-helix-zipper protein
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Suppression of Par-4 protects human renal proximal tubule cells from apoptosis induced by oxidative stress.
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Delayed Treatment with Plasminogen Activator Inhibitor-1 Decoys Reduces Tubulointerstitial Fibrosis
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28 November 2018
Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells.
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Serine proteases, inhibitors and receptors in renal fibrosis.
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28 November 2018
Integration of non-SMAD and SMAD signaling in TGF-beta1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells.
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28 November 2018
Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension
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28 November 2018
Attenuation of interstitial fibrosis and tubular apoptosis in db/db transgenic mice overexpressing catalase in renal proximal tubular cells
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28 November 2018
TGF-beta1 siRNA suppresses the tubulointerstitial fibrosis in the kidney of ureteral obstruction
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28 November 2018
Telmisartan inhibits both oxidative stress and renal fibrosis after unilateral ureteral obstruction in acatalasemic mice.
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28 November 2018
Multifunctionality of PAI-1 in fibrogenesis: evidence from obstructive nephropathy in PAI-1-overexpressing mice.
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28 November 2018
Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent
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28 November 2018
Characterization of an animal model of spontaneous congenital unilateral obstructive uropathy by cDNA microarray analysis
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28 November 2018
Acatalasemia sensitizes renal tubular epithelial cells to apoptosis and exacerbates renal fibrosis after unilateral ureteral obstruction.
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DNA oligonucleotide microarray technology identifies fisp-12 among other potential fibrogenic genes following murine unilateral ureteral obstruction (UUO): modulation during epithelial-mesenchymal transition
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28 November 2018
PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction
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28 November 2018
Transforming growth factor-beta 1 stimulates angiotensinogen gene expression in kidney proximal tubular cells
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Catalase overexpression prevents hypertension and tubular apoptosis in angiotensinogen transgenic mice
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https://pubmed.ncbi.nlm.nih.gov/23063463
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Obstructive uropathy
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stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23063463
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Overexpression of upstream stimulatory factor 2 accelerates diabetic kidney injury
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/23063463
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High glucose upregulates upstream stimulatory factor 2 in human renal proximal tubular cells through angiotensin II-dependent activation of CREB.
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/23063463
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELLSIG.2012.10.003
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4033775
OpenCitations bibliographic resource ID
4033775
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4033775
PMC publication ID
3508263
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4033775
PubMed publication ID
23063463
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4033775
ResearchGate publication ID
232246352
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