(Q27027720)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

review article

2 references

23 July 2020

Genetic risk prediction in complex disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

genetic predisposition to disease

11 February 2020

main subject

1 reference

23 July 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1

Luke Jostins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

1 reference

25 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

15 October 2011

1 reference

23 July 2020

Human Molecular Genetics

4 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

23 July 2020

10 September 2020

20

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

R2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

R182-8

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

11 February 2020

copyright license

2 references

23 July 2020

A two-stage meta-analysis identifies several new loci for Parkinson's disease

10 September 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Finding the missing heritability of complex diseases

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Meta-analysis of BRCA1 and BRCA2 penetrance

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Risk assessment tools for identifying individuals at risk of developing type 2 diabetes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Evaluation of polygenic risk scores for predicting breast and prostate cancer risk

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Role of molecular genetics in transforming diagnosis of diabetes mellitus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Improved risk prediction for Crohn's disease with a multi-locus approach

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Estimating missing heritability for disease from genome-wide association studies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Carrier testing for severe childhood recessive diseases by next-generation sequencing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Effect of direct-to-consumer genomewide profiling to assess disease risk

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genome-wide association study identifies five new breast cancer susceptibility loci

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Performance of common genetic variants in breast-cancer risk models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

The genetic interpretation of area under the ROC curve in genomic profiling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Family-based genetic risk prediction of multifactorial disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Multi-locus models of genetic risk of disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Genotyping for NOD2 genetic variants and crohn disease: a metaanalysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Disclosure of APOE genotype for risk of Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Prediction and interaction in complex disease genetics: experience in type 1 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Predicting the 30-year risk of cardiovascular disease: the framingham heart study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Detecting shared pathogenesis from the shared genetics of immune-related diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Clinical risk factors, DNA variants, and the development of type 2 diabetes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

The LLP risk model: an individual risk prediction model for lung cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

Narrative review: Assessment of C-reactive protein in risk prediction for cardiovascular disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3179379

An introduction to ROC analysis

28 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR378

Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR378

Polymorphisms associated with cholesterol and risk of cardiovascular events

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR378

Genetic variants, cardiovascular risk and genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR378

Successful implementation of a national HLA-B*5701 genetic testing service in Canada.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR378

Frequency of breast cancer attributable to BRCA1 in a population-based series of American women

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21873261

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. Anglian Breast Cancer Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/21873261

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ACOG Practice Bulletin No. 103: Hereditary breast and ovarian cancer syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21873261

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDR378

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873261%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

2 references