(Q27300811)

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AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes

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AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes (English)

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4

object named as

Marc Foretz

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Marc-André Laplante

32

object named as

Marc-André Laplante

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object named as

Benoit Viollet

35

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author name string

Yonchu Jenkins

1

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Tian-Qiang Sun

2

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Vadim Markovtsov

3

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Wei Li

5

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Henry Nguyen

6

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Yingwu Li

7

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Alison Pan

8

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Gerald Uy

9

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Lisa Gross

10

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Kristen Baltgalvis

11

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Stephanie L Yung

12

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Tarikere Gururaja

13

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Taisei Kinoshita

14

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Alexander Owyang

15

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Ira J Smith

16

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Kelly McCaughey

17

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Kathy White

18

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Guillermo Godinez

19

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Raniel Alcantara

20

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Carmen Choy

21

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Hong Ren

22

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Rachel Basile

23

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David J Sweeny

24

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Xiang Xu

25

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Sarkiz D Issakani

26

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David C Carroll

27

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Dane A Goff

28

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Simon J Shaw

29

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Rajinder Singh

30

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Laszlo G Boros

31

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Bruno Marcotte

33

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Rita Kohen

34

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André Marette

36

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Donald G Payan

37

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Todd M Kinsella

38

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Yasumichi Hitoshi

39

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language of work or name

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publication date

2013

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8

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12

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e81870

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copyright license

Creative Commons Attribution 4.0 International

5 December 2013

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3855387/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

AMP-activated protein kinase: a target for drugs both ancient and modern

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

21 March 2017

Interplay between lipids and branched-chain amino acids in development of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

21 March 2017

AMPK and PPARdelta agonists are exercise mimetics

1 reference

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21 March 2017

Mechanism by which metformin reduces glucose production in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

21 March 2017

1 reference

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21 March 2017

Demonstration of a new mammalian isoleucine catabolic pathway yielding an Rseries of metabolites

1 reference

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21 March 2017

High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria

1 reference

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21 March 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

7 April 2017

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

7 April 2017

Mitochondrial inhibitor as a new class of insulin sensitizer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

AMPK and insulin action--responses to ageing and high fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Clinical proof-of-concept study with MSDC-0160, a prototype mTOT-modulating insulin sensitizer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Increased FAT/CD36 cycling and lipid accumulation in myotubes derived from obese type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

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1 reference

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28 September 2017

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Ethylene glycol monomethyl ether-induced toxicity is mediated through the inhibition of flavoprotein dehydrogenase enzyme family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Analysis of the adult human plasma metabolome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Metformin: An Update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Physiological roles of ketone bodies as substrates and signals in mammalian tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 September 2017

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

31 May 2018

Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

31 May 2018

Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

31 May 2018

Evidence for an impaired long-chain fatty acid oxidation and ketogenesis in Fao hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

31 May 2018

On the Mechanism of Malonyl-CoA-Independent Fatty-Acid Synthesis. Different Properties of the Mitochondrial Chain Elongation and Enoyl-CoA Reductase in Various Tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

31 May 2018

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

Acute exposure to AICAR increases glucose transport in mouse EDL and soleus muscle

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

AMP kinase activation with AICAR simultaneously increases fatty acid and glucose oxidation in resting rat soleus muscle

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

Organic cation transporter 1 polymorphisms predict the metabolic response to metformin in women with the polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside and Metformin Inhibit Hepatic Glucose Phosphorylation by an AMP-Activated Protein Kinase-Independent Effect on Glucokinase Translocation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081870

21 January 2018

Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855387

28 November 2018

Differential oxidation of individual dietary fatty acids in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24339975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0081870

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2013PLoSO...881870J

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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