(Q27312512)

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Metabolic remodeling in moderate synchronous versus dyssynchronous pacing-induced heart failure: integrated metabolomics and proteomics study

scientific article (publication date: 2015)

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scholarly article

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Metabolic remodeling in moderate synchronous versus dyssynchronous pacing-induced heart failure: integrated metabolomics and proteomics study (English)

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1 reference

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James Cox

3

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author name string

Junko Shibayama

1

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Tatiana N Yuzyuk

2

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Aman Makaju

4

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Mickey Miller

5

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Justin Lichter

6

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Hui Li

7

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Jane D Leavy

8

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Sarah Franklin

9

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Alexey V Zaitsev

10

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publication date

2015

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10

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3

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e0118974

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Creative Commons Attribution 4.0 International

19 March 2015

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April 2022 Public Data File from Crossref

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2-Aminoadipic acid is a biomarker for diabetes risk

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21 March 2017

Metabolic determinants of electrical failure in ex-vivo canine model of cardiac arrest: evidence for the protective role of inorganic pyrophosphate

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21 March 2017

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

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21 March 2017

Targeting myocardial substrate metabolism in heart failure: potential for new therapies

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21 March 2017

Heart Disease and Stroke Statistics--2010 Update: A Report From the American Heart Association

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21 March 2017

MetaboAnalyst: a web server for metabolomic data analysis and interpretation

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21 March 2017

Cytosolic fatty acid binding proteins catalyze two distinct steps in intracellular transport of their ligands

2 references

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21 March 2017

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

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7 April 2017

Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy.

1 reference

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28 September 2017

Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Hexokinase-mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Proteomic profiling implies mitochondrial dysfunction in tachycardia-induced heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Increased expression of fatty-acid and calcium metabolism genes in failing human heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

PPARα-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathway.

1 reference

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28 September 2017

Galphas-biased beta2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Reciprocal transcriptional regulation of metabolic and signaling pathways correlates with disease severity in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Cardiac anaplerosis in health and disease: food for thought

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Modulating fatty acid oxidation in heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Bioenergetics of the failing heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Defective DNA replication impairs mitochondrial biogenesis in human failing hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Metabolic response to iron deficiency in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Myocardial fatty acid metabolism in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Electrophysiological consequences of dyssynchronous heart failure and its restoration by resynchronization therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

PGC-1alpha and ERRalpha target gene downregulation is a signature of the failing human heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Energy metabolism in heart failure and remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Key pathways associated with heart failure development revealed by gene networks correlated with cardiac remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

On the hypothesis that the failing heart is energy starved: lessons learned from the metabolism of ATP and creatine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Metabolic and genetic regulation of cardiac energy substrate preference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Is the failing heart energy starved? On using chemical energy to support cardiac function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Assessment of myocardial fatty acid metabolic abnormalities in patients with idiopathic dilated cardiomyopathy using 123I BMIPP SPECT: correlation with clinicopathological findings and clinical course

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 September 2017

Subcellular structures and function of myocytes impaired during heart failure are restored by cardiac resynchronization therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

31 May 2018

Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

31 May 2018

A reevaluation of the roles of hexokinase I and II in the heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

31 May 2018

Bioenergetic protection of failing atrial and ventricular myocardium by vasopeptidase inhibitor omapatrilat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

31 May 2018

Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

31 May 2018

Rate dependence of [Na+]i and contractility in nonfailing and failing human myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

31 May 2018

Energy status of the rapidly paced canine myocardium in congestive heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

31 May 2018

QRS duration and mortality in patients with congestive heart failure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Impaired myocardial fatty acid oxidation and reduced protein expression of retinoid X receptor-alpha in pacing-induced heart failure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Quantitative proteomics reveals subset-specific viral recognition in dendritic cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Metabolic gene expression in fetal and failing human heart

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Hexokinase II protein content is a determinant of exercise endurance capacity in the mouse

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Upregulation of the cardiac monocarboxylate transporter MCT1 in a rat model of congestive heart failure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Disturbed carnitine regulation in chronic heart failure--increased plasma levels of palmitoyl-carnitine are associated with poor prognosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Proteomic analysis of left ventricular remodeling in an experimental model of heart failure

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Cardiac PPARalpha expression in patients with dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0118974

21 January 2018

Peroxisome proliferator-activated receptor alpha is downregulated in the failing human heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366225

28 November 2018

Oscillations and efficiency in glycolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

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Rapid ventricular pacing in the dog: pathophysiologic studies of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental congestive heart failure produced by rapid ventricular pacing in the dog: cardiac effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endomyocardial gene expression during development of pacing tachycardia-induced heart failure in the dog

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid oxidation enzyme gene expression is downregulated in the failing heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progressive loss of myocardial ATP due to a loss of total purines during the development of heart failure in dogs: a compensatory role for the parallel loss of creatine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repolarization abnormalities, arrhythmia and sudden death in canine tachycardia-induced cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PHASE RELATIONSHIP OF GLYCOLYTIC INTERMEDIATES IN YEAST CELLS WITH OSCILLATORY METABOLIC CONTROL

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissociation between gene and protein expression of metabolic enzymes in a rodent model of heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Human Myocardial Proteome in Inflammatory Dilated Cardiomyopathy by Label-free Quantitative Shotgun Proteomics of Heart Biopsies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial carnitine and carnitine palmitoyltransferase deficiencies in patients with severe heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma carnitine levels as a marker of impaired left ventricular functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional alterations in protein expression in the dyssynchronous failing heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/25790351

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0118974

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2015PLoSO..1018974S

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