(Q27313759)

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A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo

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14 February 2020

A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo (English)

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14 February 2020

Beatrice H. Hahn

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Cristian Apetrei

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Ronald G Collman

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Mirko Paiardini

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14 February 2020

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Donald L Sodora

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Emilia A Hermann

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Lamorris M Loftin

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Sarah T Elliott

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Winston C Wey

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Jessica Taaffe

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Bing Li

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Yingying Li

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14 February 2020

Cynthia A Derdeyn

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26 August 2010

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14 February 2020

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14 February 2020

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Creative Commons Attribution 4.0 International

26 August 2010

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0 references

Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts

1 reference

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21 March 2017

Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

1 reference

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21 March 2017

Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection

1 reference

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21 March 2017

Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization

1 reference

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21 March 2017

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

1 reference

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21 March 2017

Simian immunodeficiency virus infection in free-ranging sooty mangabeys (Cercocebus atys atys) from the Taï Forest, Côte d'Ivoire: implications for the origin of epidemic human immunodeficiency virus type 2.

1 reference

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21 March 2017

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

21 March 2017

High Virus Loads in Naturally and Experimentally SIVagm-Infected African Green Monkeys

1 reference

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21 March 2017

Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

1 reference

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21 March 2017

Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection

1 reference

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21 March 2017

Expression cloning of new receptors used by simian and human immunodeficiency viruses

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21 March 2017

"Ground truth" for selection on CCR5-Delta32

1 reference

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21 March 2017

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

1 reference

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7 April 2017

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

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7 April 2017

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

1 reference

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7 April 2017

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

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7 April 2017

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

1 reference

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7 April 2017

A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation

1 reference

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28 September 2017

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

1 reference

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28 September 2017

Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

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28 September 2017

Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways

1 reference

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28 September 2017

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

1 reference

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28 September 2017

Early divergence in neutrophil apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates.

1 reference

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28 September 2017

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

1 reference

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28 September 2017

Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Paucity of CD4+ CCR5+ T cells may prevent transmission of simian immunodeficiency virus in natural nonhuman primate hosts by breast-feeding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut.

1 reference

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28 September 2017

Understanding the benign nature of SIV infection in natural hosts

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28 September 2017

Species selectivity of small-molecular antagonists for the CCR5 chemokine receptor

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28 September 2017

Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection

1 reference

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28 September 2017

Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys

1 reference

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28 September 2017

Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys

1 reference

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28 September 2017

Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

1 reference

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28 September 2017

In vitro characterization of primary SIVsmm isolates belonging to different lineages. In vitro growth on rhesus macaque cells is not predictive for in vivo replication in rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Comparative studies on mucosal and intravenous transmission of simian immunodeficiency virus (SIVsm): evolution of coreceptor use varies with pathogenic outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Molecular epidemiology of simian immunodeficiency virus SIVsm in U.S. primate centers unravels the origin of SIVmac and SIVstm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons.

1 reference

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28 September 2017

Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Early- and intermediate-stage variants of simian immunodeficiency virus replicate efficiently in cells lacking CCR5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

The dynamics of CD4+ T-cell depletion in HIV disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Differential coreceptor expression allows for independent evolution of non-syncytium-inducing and syncytium-inducing HIV-1.

1 reference

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28 September 2017

The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Expression and coreceptor activity of STRL33/Bonzo on primary peripheral blood lymphocytes

1 reference

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28 September 2017

Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Simian immunodeficiency viruses of diverse origin can use CXCR4 as a coreceptor for entry into human cells

1 reference

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28 September 2017

In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline

1 reference

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28 September 2017

Co-receptor usage of BOB/GPR15 in addition to CCR5 has no significant effect on replication of simian immunodeficiency virus in vivo

1 reference

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28 September 2017

Natural infection of a homozygous delta24 CCR5 red-capped mangabey with an R2b-tropic simian immunodeficiency virus.

1 reference

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28 September 2017

Primary SIVsm isolates use the CCR5 coreceptor from sooty mangabeys naturally infected in west Africa: a comparison of coreceptor usage of primary SIVsm, HIV-2, and SIVmac

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2928783

28 September 2017

Natural infection of a household pet red-capped mangabey (Cercocebus torquatus torquatus) with a new simian immunodeficiency virus

1 reference

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28 September 2017

Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses

1 reference

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28 September 2017

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.

1 reference

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28 September 2017

Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry

1 reference

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28 September 2017

Isolation of simian immunodeficiency viruses from two sooty mangabeys in Côte d'Ivoire: virological and genetic characterization and relationship to other HIV type 2 and SIVsm/mac strains

1 reference

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28 September 2017

Engineering human monoclonal antibody fragments: a recombinant enzyme-linked Fab.

1 reference

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28 September 2017

Hybrid origin of SIV in chimpanzees.

1 reference

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31 May 2018

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

1 reference

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31 May 2018

Parallel evolution of CCR5-null phenotypes in humans and in a natural host of simian immunodeficiency virus.

1 reference

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31 May 2018

Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.

1 reference

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31 May 2018

A new SIV co-receptor, STRL33.

1 reference

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19 June 2018

An African primate lentivirus (SIVsm) closely related to HIV-2.

1 reference

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21 January 2018

Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

1 reference

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21 January 2018

Pathogenesis of HIV infection: what the virus spares is as important as what it destroys

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21 January 2018

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

1 reference

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21 January 2018

Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001064

21 January 2018

Effect of a CCR5 inhibitor on viral loads in macaques dual-infected with R5 and X4 primate immunodeficiency viruses

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001064

21 January 2018

Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001064

21 January 2018

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001064

21 January 2018

Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of

1 reference

https://pubmed.ncbi.nlm.nih.gov/20865163

12 December 2020

based on heuristic

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10.1371/JOURNAL.PPAT.1001064

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20865163%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20865163%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20865163%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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