(Q27324132)

26 June 2017

title

Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development (English)

1 reference

26 June 2017

main subject

Plasmodium falciparum

0 references

0 references

1

1 reference

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2 June 2020

Paul Griffin

6

1 reference

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Rob Hooft van Huijsduijnen

2 June 2020

14

1 reference

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2 June 2020

Stephan Duparc

15

1 reference

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2 June 2020

Timothy N C Wells

17

1 reference

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2 June 2020

Iñigo Angulo-Barturen

10

object named as

Iñigo Angulo-Barturen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044554%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Louise Marquart

2

1 reference

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2 June 2020

Silvana Sekuloski

3

1 reference

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2 June 2020

Katharine Trenholme

4

1 reference

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2 June 2020

Suzanne Elliott

5

1 reference

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2 June 2020

Rebecca Rockett

7

1 reference

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2 June 2020

Peter O'Rourke

8

1 reference

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2 June 2020

Theo Sloots

9

1 reference

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2 June 2020

Santiago Ferrer

11

1 reference

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2 June 2020

María Belén Jiménez-Díaz

12

1 reference

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2 June 2020

María-Santos Martínez

13

1 reference

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2 June 2020

Didier Leroy

16

1 reference

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2 June 2020

Mark Baker

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044554%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Jörg J Möhrle

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044554%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

4 April 2016

1 reference

Antimicrobial Agents and Chemotherapy

26 June 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044554%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

60

1 reference

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2 June 2020

issue

6

1 reference

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2 June 2020

page(s)

3669-3675

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044554%20AND%20SRC:MED&resulttype=core&format=json

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

2 June 2020

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1 reference

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21 March 2017

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21 March 2017

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Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes

21 March 2017

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A pilot randomised trial of induced blood-stage Plasmodium falciparum infections in healthy volunteers for testing efficacy of new antimalarial drugs

21 March 2017

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A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes

21 March 2017

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21 March 2017

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Hit and lead criteria in drug discovery for infectious diseases of the developing world

21 March 2017

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How Robust Are Malaria Parasite Clearance Rates as Indicators of Drug Effectiveness and Resistance?

28 September 2017

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Evaluating the pharmacodynamic effect of antimalarial drugs in clinical trials by quantitative PCR

28 September 2017

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Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

28 September 2017

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Scientific and regulatory reasons for delay and denial of FDA approval of initial applications for new drugs, 2000-2012.

28 September 2017

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Experimentally induced blood stage malaria infection as a tool for clinical research.

28 September 2017

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The parasite clearance curve

28 September 2017

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Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity

28 September 2017

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The relevance of non-human primate and rodent malaria models for humans

28 September 2017

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Host immunity as a determinant of treatment outcome in Plasmodium falciparum malaria

28 September 2017

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28 September 2017

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Mechanism-based pharmacokinetic-pharmacodynamic modeling of antimicrobial drug effects

28 September 2017

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28 September 2017

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Cerebral uptake of mefloquine enantiomers with and without the P-gp inhibitor elacridar (GF1210918) in mice

28 September 2017

1 reference

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28 September 2017

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Population pharmacokinetics of mefloquine in patients with acute falciparum malaria

28 September 2017

1 reference

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28 September 2017

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28 September 2017

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28 September 2017

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A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers

28 September 2017

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Measurement of Plasmodium falciparum growth rates in vivo: a test of malaria vaccines

2 June 2018

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2 June 2018

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Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model

2 June 2018

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Experimental human challenge infections can accelerate clinical malaria vaccine development

27 November 2018

1 reference

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Quantitative measurement of Plasmodium-infected erythrocytes in murine models of malaria by flow cytometry using bidimensional assessment of SYTO-16 fluorescence

27 November 2018

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27 November 2018

Identifiers

DOI

10.1128/AAC.02883-15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044554%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

2 June 2020

2497054

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2497054

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27044554%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference