(Q27324246)

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Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice

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Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice (English)

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Jeremy Veenstra-VanderWeele

12

object named as

Jeremy Veenstra-Vanderweele

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Michael A Siuta

object named as

Michael A Siuta

1

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Sabrina D Robertson

object named as

Sabrina D Robertson

2

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object named as

Gregg D Stanwood

13

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object named as

Mark A Magnuson

14

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Craig W. Lindsley

9

object named as

Craig W Lindsley

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author name string

Heidi Kocalis

3

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Christine Saunders

4

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Paul J Gresch

5

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Vivek Khatri

6

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Chiyo Shiota

7

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J Philip Kennedy

8

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Lynette C Daws

10

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Daniel B Polley

11

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Kevin D Niswender

15

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Aurelio Galli

16

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publication date

2010

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8

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6

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e1000393

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Creative Commons Attribution 4.0 International

8 June 2010

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April 2022 Public Data File from Crossref

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The dopamine hypothesis of schizophrenia: version III--the final common pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

21 March 2017

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

21 March 2017

Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling

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21 March 2017

Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

21 March 2017

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

21 March 2017

Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

1 reference

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21 March 2017

Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists

1 reference

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21 March 2017

The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice

1 reference

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21 March 2017

The relationship among neuregulin 1-stimulated phosphorylation of AKT, psychosis proneness, and habituation of arousal in nonclinical individuals

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28 September 2017

Prepulse inhibition and genetic mouse models of schizophrenia

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28 September 2017

A randomized double-blind trial of atomoxetine for cognitive impairments in 32 people with schizophrenia

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28 September 2017

Akt/GSK3 signaling in the action of psychotropic drugs

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28 September 2017

AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli.

1 reference

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28 September 2017

Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans

1 reference

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28 September 2017

Neuregulin-1 regulates cell adhesion via an ErbB2/phosphoinositide-3 kinase/Akt-dependent pathway: potential implications for schizophrenia and cancer

1 reference

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28 September 2017

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

28 September 2017

Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

28 September 2017

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

1 reference

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28 September 2017

The effects of clozapine on the GSK-3-mediated signaling pathway

1 reference

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28 September 2017

EFFECT OF CHLORPROMAZINE OR HALOPERIDOL ON FORMATION OF 3METHOXYTYRAMINE AND NORMETANEPHRINE IN MOUSE BRAIN.

1 reference

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Therapeutic use in psychiatry of phenothiazine of central elective action (4560 RP)

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28 September 2017

PI 3-kinase regulation of dopamine uptake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

28 September 2017

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

1 reference

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28 September 2017

Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme

1 reference

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28 September 2017

Antipsychotic drug actions: a clue to the neuropathology of schizophrenia?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

28 September 2017

Dopamine in schizophrenia: a review and reconceptualization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

28 September 2017

The dopamine hypothesis of schizophrenia: focus on the dopamine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

28 September 2017

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

2 June 2018

Regulation of extracellular dopamine by the norepinephrine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

2 June 2018

Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: a molecular study

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2 June 2018

Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

2 June 2018

The effect of insulin on norepinephrine uptake by PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

2 June 2018

Schizophrenia: elevated cerebrospinal fluid norepinephrine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

2 June 2018

Insulin inhibits specific norepinephrine uptake in neuronal cultures from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

2 June 2018

Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. III. A new cohort and evidence for a monoaminergic mechanism.

1 reference

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2 June 2018

Antipsychotic Drugs: Direct Correlation Between Clinical Potency and Presynaptic Action on Dopamine Neurons

1 reference

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2 June 2018

Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways

1 reference

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21 January 2018

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction

1 reference

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21 January 2018

Alteration in kinase activity but not in protein levels of protein kinase B and glycogen synthase kinase-3beta in ventral prefrontal cortex of depressed suicide victims

1 reference

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21 January 2018

Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1000393

21 January 2018

Ultrastructural localization of the norepinephrine transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to probable dopamine terminals

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1000393

21 January 2018

Forebrain D1 function and sensorimotor gating in rats: effects of D1 blockade, frontal lesions and dopamine denervation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1000393

21 January 2018

Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1000393

21 January 2018

Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1000393

21 January 2018

Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1000393

21 January 2018

Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

27 November 2018

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1 reference

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27 November 2018

Norepinephrine in the prefrontal cortex is critical for amphetamine-induced reward and mesoaccumbens dopamine release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882427

27 November 2018

Local influence of endogenous norepinephrine on extracellular dopamine in rat medial prefrontal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/20543991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20543991

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PBIO.1000393

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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