(Q27334236)

English

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice

scientific article (publication date: 2016)

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3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice (English)

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Peter Davies

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object named as

Hongjun Fu

1

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9

object named as

Bradley T Hyman

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Syed Abid Hussaini

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ORCID Public Data File 2021

author name string

S Abid Hussaini

2

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Susanne Wegmann

3

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Caterina Profaci

4

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Jacob D Daniels

5

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Mathieu Herman

6

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Sheina Emrani

7

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Helen Y Figueroa

8

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Karen E Duff

11

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publication date

2016

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11

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e0159463

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Creative Commons Attribution 4.0 International

28 July 2016

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April 2022 Public Data File from Crossref

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4965059/fullTextXML

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inferred from PubMed Central ID database lookup

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

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21 March 2017

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

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Chemical clearing and dehydration of GFP expressing mouse brains

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Neuropathological alterations in Alzheimer disease

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

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Memory dysfunction

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Trans-synaptic spread of tau pathology in vivo

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7 April 2017

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Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

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7 April 2017

Tau suppression in a neurodegenerative mouse model improves memory function

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28 September 2017

Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody.

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28 September 2017

Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex

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Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

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28 September 2017

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model

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28 September 2017

Lateral entorhinal cortex is necessary for associative but not nonassociative recognition memory.

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28 September 2017

Lateral entorhinal cortex is critical for novel object-context recognition.

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28 September 2017

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28 September 2017

Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits

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28 September 2017

Perirhinal cortex represents nonspatial, but not spatial, information in rats foraging in the presence of objects: comparison with lateral entorhinal cortex

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28 September 2017

Amygdala atrophy is prominent in early Alzheimer's disease and relates to symptom severity

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28 September 2017

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The caudal medial entorhinal cortex: a selective role in recollection-based recognition memory

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28 September 2017

Post-training reversible inactivation of the hippocampus enhances novel object recognition memory

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28 September 2017

Memory loss in Alzheimer's disease: implications for development of therapeutics

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28 September 2017

Microglial activation in brain lesions with tau deposits: comparison of human tauopathies and tau transgenic mice TgTauP301L.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4965059

28 September 2017

Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau

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28 September 2017

The role of the perirhinal cortex and hippocampus in learning, memory, and perception

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28 September 2017

Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice

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28 September 2017

Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein

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28 September 2017

Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau.

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28 September 2017

Glial inclusions in CNS degenerative diseases.

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28 September 2017

Immunocytochemical characterization of glial fibrillary tangles in Alzheimer's disease brain.

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28 September 2017

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28 September 2017

Genetic background modifies neurodegeneration and neuroinflammation driven by misfolded human tau protein in rat model of tauopathy: implication for immunomodulatory approach to Alzheimer's disease

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2 June 2018

Sequence requirements for formation of conformational variants of tau similar to those found in Alzheimer's disease.

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2 June 2018

Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages.

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2 June 2018

Presence of both odor identification and detection deficits in Alzheimer's disease.

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2 June 2018

Paired helical filaments in astrocytes: electron microscopy and immunohistochemistry in a case of atypical Alzheimer's disease

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ScaleS: an optical clearing palette for biological imaging.

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21 January 2018

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CLARITY for mapping the nervous system

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21 January 2018

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

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21 January 2018

Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease

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21 January 2018

Olfactory deficits in patients with mild cognitive impairment predict Alzheimer's disease at follow-up.

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21 January 2018

CaMKII activation in the entorhinal cortex disrupts previously encoded spatial memory.

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21 January 2018

Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy.

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21 January 2018

Microglia display modest phagocytic capacity for extracellular tau oligomers

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0159463

21 January 2018

Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation

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21 January 2018

Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant.

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21 January 2018

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27 November 2018

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

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27 November 2018

Object recognition and object orientation in Alzheimer's disease

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12 December 2020

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10.1371/JOURNAL.PONE.0159463

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2016PLoSO..1159463F

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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