(Q27334826)

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Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease

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Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease (English)

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Parkinson's disease

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Richard J Smeyne

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Richard Smeyne

17

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Craig A Stockmeier

13

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Craig Stockmeier

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author name string

Samuel O Adeosun

1

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Xu Hou

2

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Yun Jiao

3

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Baoying Zheng

4

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Sherry Henry

5

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Rosanne Hill

6

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Zhi He

7

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Amar Pani

8

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Patrick Kyle

9

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Xiaoming Ou

10

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Thomas Mosley

11

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Jerry M Farley

12

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Ian Paul

14

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Steven Bigler

15

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Roberta Diaz Brinton

16

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Jun Ming Wang

18

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publication date

2012

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7

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11

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e50040

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Creative Commons Attribution 4.0 International

29 November 2012

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April 2022 Public Data File from Crossref

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0 references

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1 reference

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Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease

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Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis

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Evidence for neurogenesis in the adult mammalian substantia nigra

1 reference

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The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression

1 reference

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Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease

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Calcium and neurogenesis in Alzheimer's disease

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Mutant α-synuclein and aging reduce neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

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Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain.

1 reference

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Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration

1 reference

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Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.

1 reference

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Exercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse

1 reference

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1 reference

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Sex differences in motor behavior in the MPTP mouse model of Parkinson's disease

1 reference

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Exercise protects against MPTP-induced neurotoxicity in mice.

1 reference

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Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinson's disease

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Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential

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Fibroblast growth factor 2 enhances striatal and nigral neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

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Regeneration in a degenerating brain: potential of allopregnanolone as a neuroregenerative agent

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Regenerative potential of allopregnanolone

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Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice

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1 reference

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1 reference

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1 reference

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Effective control of catatonia in Parkinson's disease by electroconvulsive therapy: a case report

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The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism.

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Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade

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21 January 2018

Neurosteroid biosynthetic pathway changes in substantia nigra and caudate nucleus in Parkinson's disease

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27 November 2018

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midbrain dopaminergic neurons in the mouse: computer-assisted mapping

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https://pubmed.ncbi.nlm.nih.gov/23209637

12 December 2020

based on heuristic

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[Current status of gene therapy for Parkinson disease]

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https://pubmed.ncbi.nlm.nih.gov/23209637

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based on heuristic

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Motor coordination and balance in rodents

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10.1371/JOURNAL.PONE.0050040

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2012PLoSO...750040A

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