(Q27334826)

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Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease

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Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease (English)

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Parkinson's disease

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Richard J Smeyne

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Richard Smeyne

17

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Craig A Stockmeier

13

object named as

Craig Stockmeier

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author name string

Samuel O Adeosun

1

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Xu Hou

2

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Yun Jiao

3

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Baoying Zheng

4

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Sherry Henry

5

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Rosanne Hill

6

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Zhi He

7

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Amar Pani

8

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Patrick Kyle

9

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Xiaoming Ou

10

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Thomas Mosley

11

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Jerry M Farley

12

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Ian Paul

14

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Steven Bigler

15

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Roberta Diaz Brinton

16

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Jun Ming Wang

18

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publication date

2012

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7

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11

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e50040

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Creative Commons Attribution 4.0 International

29 November 2012

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April 2022 Public Data File from Crossref

copyright status

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Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche

1 reference

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Adult neurogenesis in the mammalian brain: significant answers and significant questions

1 reference

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Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease

1 reference

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Stem cells in human neurodegenerative disorders--time for clinical translation?

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1 reference

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Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis

1 reference

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Evidence for neurogenesis in the adult mammalian substantia nigra

1 reference

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21 March 2017

The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression

1 reference

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21 March 2017

Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease

1 reference

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Ontogeny of 5 alpha-reductase (type 1) messenger ribonucleic acid expression in rat brain: early presence in germinal zones

1 reference

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Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice

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Progesterone treatment normalizes the levels of cell proliferation and cell death in the dentate gyrus of the hippocampus after traumatic brain injury

1 reference

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Calcium and neurogenesis in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

29 September 2017

Mutant α-synuclein and aging reduce neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

29 September 2017

Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

29 September 2017

Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

29 September 2017

Adult neurogenesis without germinal layers: the "atypical" cerebellum of rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

29 September 2017

Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

29 September 2017

Exercise effects on motor and affective behavior and catecholamine neurochemistry in the MPTP-lesioned mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Neurogenesis in substantia nigra of parkinsonian brains?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Sex differences in motor behavior in the MPTP mouse model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Exercise protects against MPTP-induced neurotoxicity in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Engineering the CNS stem cell microenvironment

1 reference

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Exercise exerts neuroprotective effects on Parkinson's disease model of rats

1 reference

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Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

1 reference

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Effects of UCH-L1 on alpha-synuclein over-expression mouse model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

29 September 2017

Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential

1 reference

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Fibroblast growth factor 2 enhances striatal and nigral neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

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Regeneration in a degenerating brain: potential of allopregnanolone as a neuroregenerative agent

1 reference

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Regenerative potential of allopregnanolone

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Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta

1 reference

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Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice

1 reference

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Norepinephrine: The redheaded stepchild of Parkinson's disease

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Adult mammalian neurogenesis and the New Zealand white rabbit

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The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease

1 reference

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Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion

1 reference

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29 September 2017

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1 reference

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29 September 2017

The MPTP model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Brain neurosteroids in gender-related aggression induced by social isolation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Sonic hedgehog facilitates dopamine differentiation in the presence of a mesencephalic glial cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Generation of tyrosine hydroxylase-producing neurons from precursors of the embryonic and adult forebrain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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TRK-820, a selective kappa opioid receptor agonist, could effectively ameliorate L-DOPA-induced dyskinesia symptoms in a rat model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

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Neurosteroid dehydroepiandrosterone exerts anti-apoptotic effects by membrane-mediated, integrated genomic and non-genomic pro-survival signaling pathways

1 reference

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Role of allopregnanolone on cerebellar granule cells neurogenesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Physical exercise induces FGF-2 and its mRNA in the hippocampus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

21 January 2018

Effective control of catatonia in Parkinson's disease by electroconvulsive therapy: a case report

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration model.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Dopamine controls neurogenesis in the adult salamander midbrain in homeostasis and during regeneration of dopamine neurons.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Localization and fate of Fgf10-expressing cells in the adult mouse brain implicate Fgf10 in control of neurogenesis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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A subpial, transitory germinal zone forms chains of neuronal precursors in the rabbit cerebellum.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Possibility for neurogenesis in substantia nigra of parkinsonian brain

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Antidepressant imipramine induces human astrocytes to differentiate into cells with neuronal phenotype.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

21 January 2018

3alpha,5alpha-Tetrahydroprogesterone (allopregnanolone) and gamma-aminobutyric acid: autocrine/paracrine interactions in the control of neonatal PSA-NCAM+ progenitor proliferation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

21 January 2018

In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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Decreased plasma and cerebrospinal fluid content of neuroactive steroids in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

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The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

21 January 2018

The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

21 January 2018

Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050040

21 January 2018

Neurosteroid biosynthetic pathway changes in substantia nigra and caudate nucleus in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3510204

27 November 2018

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23209637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midbrain dopaminergic neurons in the mouse: computer-assisted mapping

1 reference

https://pubmed.ncbi.nlm.nih.gov/23209637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Current status of gene therapy for Parkinson disease]

1 reference

https://pubmed.ncbi.nlm.nih.gov/23209637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor coordination and balance in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/23209637

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based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0050040

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2012PLoSO...750040A

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