(Q36156158)

English

Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

substantia nigra

1 reference

based on heuristic

inferred from title

author name string

Justin D Boyd

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Haeman Jang

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Kennie R Shepherd

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Ciaran Faherty

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Sally Slack

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Yun Jiao

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Richard J Smeyne

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

0 references

publication date

9 August 2007

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Europe PubMed Central

PMC publication ID

12 August 2017

number of pages

10

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based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

1175

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

107-116

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

The MPTP model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

The herbicide paraquat induces dopaminergic nigral apoptosis through sustained activation of the JNK pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Recent advances in research on Parkinson disease: synuclein and parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Parkinson's disease: mechanisms and models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

COX-2 and neurodegeneration in Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Neuroinflammatory processes in Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

The last decade in Parkinson's disease research. Basic sciences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Inhibition of brain vesicular monoamine transporter (VMAT2) enhances 1-methyl-4-phenylpyridinium neurotoxicity in vivo in rat striata

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Etiology and pathogenesis of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Parkinson's disease, pesticides, and glutathione transferase polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

MPTP, MPP+ and mitochondrial function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 October 2017

Time-course and dose-response study on the effects of chronic L-DOPA administration on striatal dopamine levels and dopamine transporter following MPTP toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Differential strain susceptibility following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration acts in an autosomal dominant fashion: quantitative analysis in seven strains of Mus musculus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Expression of c-Jun in dopaminergic neurons of the substantia nigra in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Differential neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in Swiss-Webster mice from different sources.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

The neurochemical and clinical effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in small animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and methamphetamine in several strains of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

2 July 2018

Glia cell number modulates sensitivity to MPTP in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E(2) secretion by cultured human adult microglia: implications for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

In vitro studies of striatal vesicles containing the vesicular monoamine transporter (VMAT2): rat versus mouse differences in sequestration of 1-methyl-4-phenylpyridinium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084084

23 September 2018

Identification of a glutathione-S-transferase effector domain for inhibition of jun kinase, by molecular dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in C57BL/6 mice. Comparison with three other strains of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the melanin affinity of selegiline (deprenyl) and other amphetamine derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acute effect on levels of catecholamines and metabolites in brain, of a single dose of MPTP in 8 strains of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPTP- and MPP(+)-induced effects on body temperature exhibit age- and strain-dependence in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17884023

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BRAINRES.2007.07.067

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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